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Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…
Background: Automated segmentation of spinal MR images plays a vital role both scientifically and clinically. However, accurately delineating posterior spine structures presents challenges. Methods: This retrospective study, approved by the…
Transformer, benefiting from global (long-range) information modeling using self-attention mechanism, has been successful in natural language processing and computer vision recently. Convolutional Neural Networks, capable of capturing local…
Efficient and accurate brain ventricle segmentation from clinical CT scans is critical for emergency surgeries like ventriculostomy. With the challenges in poor soft tissue contrast and a scarcity of well-annotated databases for clinical…
Diffusion bridge models and stochastic interpolants enable high-quality image-to-image (I2I) translation by creating paths between distributions in pixel space. However, the proliferation of techniques based on incompatible mathematical…
Diffusion-weighted (DW) magnetic resonance imaging is essential for the diagnosis and treatment of ischemic stroke. DW images (DWIs) are usually acquired in multi-slice settings where lesion areas in two consecutive 2D slices are highly…
Segmentation of 3D medical images is a critical task for accurate diagnosis and treatment planning. Convolutional neural networks (CNNs) have dominated the field, achieving significant success in 3D medical image segmentation. However, CNNs…
The rapid development in representation learning techniques such as deep neural networks and the availability of large-scale, well-annotated medical imaging datasets have to a rapid increase in the use of supervised machine learning in the…
Neuroimaging to neuropathology correlation (NTNC) promises to enable the transfer of microscopic signatures of pathology to in vivo imaging with MRI, ultimately enhancing clinical care. NTNC traditionally requires a volumetric MRI scan,…
In radiation therapy (RT), the reliance on pre-treatment computed tomography (CT) images encounter challenges due to anatomical changes, necessitating adaptive planning. Daily cone-beam CT (CBCT) imaging, pivotal for therapy adjustment,…
Accurate segmentation of brain tumors in MRI scans is essential for reliable clinical diagnosis and effective treatment planning. Recently, diffusion models have demonstrated remarkable effectiveness in image generation and segmentation…
Multi-site structural MRI is increasingly used in neuroimaging studies to diversify subject cohorts. However, combining MR images acquired from various sites/centers may introduce site-related non-biological variations. Retrospective image…
Volumetric reconstruction of fetal brains from multiple stacks of MR slices, acquired in the presence of almost unpredictable and often severe subject motion, is a challenging task that is highly sensitive to the initialization of…
Medical image-to-image (I2I) translation enables virtual scanning, i.e. the synthesis of a target imaging modality from a source one without additional acquisitions. Despite growing interest, most proposed methods operate on 2D slices, are…
This research presents an enhanced approach for precise segmentation of brain tumor masses in magnetic resonance imaging (MRI) using an advanced 3D-UNet model combined with a Context Transformer (CoT). By architectural expansion CoT, the…
Neuropathological analyses benefit from spatially precise volumetric reconstructions that enhance anatomical delineation and improve morphometric accuracy. Our prior work has shown the feasibility of reconstructing 3D brain volumes from 2D…
Applying diffusion models to image-to-image translation (I2I) has recently received increasing attention due to its practical applications. Previous attempts inject information from the source image into each denoising step for an iterative…
Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…
Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…
Accurate tissue segmentation of thick-slice fetal brain magnetic resonance (MR) scans is crucial for both reconstruction of isotropic brain MR volumes and the quantification of fetal brain development. However, this task is challenging due…