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Deep neural networks are a very powerful tool for many computer vision tasks, including image restoration, exhibiting state-of-the-art results. However, the performance of deep learning methods tends to drop once the observation model used…

Accurate prediction of protein-ligand binding affinities is an essential challenge in structure-based drug design. Despite recent advances in data-driven methods for affinity prediction, their accuracy is still limited, partially because…

Traditional non-biological storage media, such as hard drives, face limitations in both storage density and lifespan due to the rapid growth of data in the big data era. Mirror-image peptides composed of D-amino acids have emerged as a…

Unsupervised deep image prior (DIP) addresses shortcomings of training data requirements and limited generalization associated with supervised deep learning. The performance of DIP depends on the network architecture and the stopping point…

Purpose: Quantitative phase imaging (QPI) is a label-free technique that provides high-contrast images of tissues and cells without the use of chemicals or dyes. Accurate semantic segmentation of cells in QPI is essential for various…

Deep image prior (DIP) has recently attracted attention owing to its unsupervised positron emission tomography (PET) image reconstruction, which does not require any prior training dataset. In this paper, we present the first attempt to…

Deep learning has been widely used for solving image reconstruction tasks but its deployability has been held back due to the shortage of high-quality training data. Unsupervised learning methods, such as the deep image prior (DIP),…

An end-to-end image analysis pipeline is presented for the abdominal MRI protocol used in the UK Biobank on the first 38,971 participants. Emphasis is on the processing steps necessary to ensure a high-level of data quality and consistency…

Deep image prior (DIP) is an unsupervised deep learning framework that has been successfully applied to a variety of inverse imaging problems. However, DIP-based methods are inherently prone to overfitting, which leads to performance…

Image denoising is often empowered by accurate prior information. In recent years, data-driven neural network priors have shown promising performance for RGB natural image denoising. Compared to classic handcrafted priors (e.g., sparsity…

This paper investigates the application of unsupervised learning methods for computed tomography (CT) reconstruction. To motivate our work, we review several existing priors, namely the truncated Gaussian prior, the $l_1$ prior, the total…

In Deep Image Prior (DIP), a Convolutional Neural Network (CNN) is fitted to map a latent space to a degraded (e.g. noisy) image but in the process learns to reconstruct the clean image. This phenomenon is attributed to CNN's internal…

Seismic images often contain both coherent and random artifacts which complicate their interpretation. To mitigate these artifacts, we introduce a novel unsupervised deep-learning method based on Deep Image Prior (DIP) which uses…

We mainly analyze and solve the overfitting problem of deep image prior (DIP). Deep image prior can solve inverse problems such as super-resolution, inpainting and denoising. The main advantage of DIP over other deep learning approaches is…

Deep image prior (DIP) serves as a good inductive bias for diverse inverse problems. Among them, denoising is known to be particularly challenging for the DIP due to noise fitting with the requirement of an early stopping. To address the…

Characterization of a patient clinical phenotype is central to biomedical informatics. ICD codes, assigned to inpatient encounters by coders, is important for population health and cohort discovery when clinical information is limited.…

Image deconvolution is the process of recovering convolutional degraded images, which is always a hard inverse problem because of its mathematically ill-posed property. On the success of the recently proposed deep image prior (DIP), we…

Deep image prior (DIP) and its variants have showed remarkable potential for solving inverse problems in computer vision, without any extra training data. Practical DIP models are often substantially overparameterized. During the fitting…

Recent advances in data-centric deep generative models have led to significant progress in solving inverse imaging problems. However, these models (e.g., diffusion models (DMs)) typically require large amounts of fully sampled (clean)…

Liquid chromatography with tandem mass spectrometry (LC-MS/MS) based proteomics is a well-established research field with major applications such as identification of disease biomarkers, drug discovery, drug design and development. In…