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The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…

Image and Video Processing · Electrical Eng. & Systems 2021-02-01 Chengyang Zhou , Thao Vy Dinh , Heyi Kong , Jonathan Yap , Khung Keong Yeo , Hwee Kuan Lee , Kaicheng Liang

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

Tissues and Organs · Quantitative Biology 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Precision medicine, tailored to individual patients based on their genetics, environment, and lifestyle, shows promise in managing complex diseases like infections. Integrating artificial intelligence (AI) into precision medicine can…

Other Quantitative Biology · Quantitative Biology 2023-07-31 Ghizal fatima , Risala H. Allami , Maitham G. Yousif

Cervical spondylosis, a complex and prevalent condition, demands precise and efficient diagnostic techniques for accurate assessment. While MRI offers detailed visualization of cervical spine anatomy, manual interpretation remains…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Lianming Wu , Kun Wang , Jianqi Sun , Hongxing Shen

This proof of concept (PoC) assesses the ability of machine learning (ML) classifiers to predict the presence of a stenosis in a three vessel arterial system consisting of the abdominal aorta bifurcating into the two common iliacs. A…

Machine Learning · Computer Science 2021-08-31 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

Machine Learning · Computer Science 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

We envision the Full-Body AI Agent as a comprehensive AI system designed to simulate, analyze, and optimize the dynamic processes of the human body across multiple biological levels. By integrating computational models, machine learning…

Tissues and Organs · Quantitative Biology 2025-08-28 Aoqi Wang , Jiajia Liu , Jianguo Wen , Yangyang Luo , Zhiwei Fan , Liren Yang , Xi Hu , Ruihan Luo , Yankai Yu , Sophia Li , Weiling Zhao , Xiaobo Zhou

Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or…

Computers and Society · Computer Science 2019-08-29 Sebastian Spänig , Agnes Emberger-Klein , Jan-Peter Sowa , Ali Canbay , Klaus Menrad , Dominik Heider

Patient-specific computational modeling has emerged as a powerful tool for surgical planning in complex congenital heart disease. One promising application is complex biventricular repair, which often requires construction of a custom…

Computational Engineering, Finance, and Science · Computer Science 2026-03-27 Elena Sabdy Martinez , Alexander D. Kaiser , Alexander K. Reed , Sascha W. Stocker , Amit Sharir , Perry S. Choi , Shiraz A. Maskatia , Michael R. Ma , Alison Lesly Marsden

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Baixiang Huang , Yu Luo , Guangyu Wei , Songyan He , Yushuang Shao , Xueying Zeng

Developing artificial intelligence (AI) and machine learning (ML) models for medical imaging typically involves extensive training and testing on large datasets, consuming significant computational time, energy, and resources. There is a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Raj Hansini Khoiwal , Alan B. McMillan

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of…

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Quantitative Methods · Quantitative Biology 2025-08-27 Julian Suk , Guido Nannini , Patryk Rygiel , Christoph Brune , Gianluca Pontone , Alberto Redaelli , Jelmer M. Wolterink

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang

Artificial intelligence-enhanced electrocardiogram (AI-ECG) has shown promise as an inexpensive, ubiquitous, and non-invasive screening tool to detect left ventricular systolic dysfunction in pediatric congenital heart disease. However,…

Computational Engineering, Finance, and Science · Computer Science 2025-11-14 Yuting Yang , Lorenzo Peracchio , Joshua Mayourian , John K. Triedman , Timothy Miller , William G. La Cava

CoronaryHemodynamics is a comprehensive simulation package developed on the OpenFOAM platform, designed specifically for coronary artery hemodynamics analysis. The package integrates a complete suite of tools for simulation preparation,…

Fluid Dynamics · Physics 2025-01-16 Yijin Mao , Yuwen Zhang

Artificial intelligence (AI) models are becoming key components in an autonomous vehicle (AV), especially in handling complicated perception tasks. However, closing the loop through AI-based feedback may pose significant risks on…

Systems and Control · Electrical Eng. & Systems 2025-09-16 Tao Yan , Zheyu Zhang , Jingjing Jiang , Wen-Hua Chen

Advancements in AI have greatly enhanced the medical imaging process, making it quicker to diagnose patients. However, very few have investigated the optimization of a multi-model system with hardware acceleration. As specialized edge…

Hardware Architecture · Computer Science 2025-10-03 Ashiyana Abdul Majeed , Mahmoud Meribout , Safa Mohammed Sali

Artificial Intelligence (AI) is poised to transform healthcare delivery through revolutionary advances in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered…

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