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While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Shahad Albastaki , Anabia Sohail , Iyyakutti Iyappan Ganapathi , Basit Alawode , Asim Khan , Sajid Javed , Naoufel Werghi , Mohammed Bennamoun , Arif Mahmood

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Xuan Gong , Kai Zhang , Pingyi Chen , Ye Zhang , Zhongyi Shui , Tao Lin , Lin Yang

Vision-Language Models (VLMs) trained via contrastive learning have achieved notable success in natural image tasks. However, their application in the medical domain remains limited due to the scarcity of openly accessible, large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Muhammad Uzair Khattak , Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Yuxuan Sun , Chenglu Zhu , Sunyi Zheng , Kai Zhang , Lin Sun , Zhongyi Shui , Yunlong Zhang , Honglin Li , Lin Yang

Recent advances in vision language models (VLMs) have enabled broad progress in the general medical field. However, pathology still remains a more challenging subdomain, with current pathology specific VLMs exhibiting limitations in both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Penghao Zhang , Jingru Guo , Tao Cheng , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

AI in dermatology is evolving at a rapid pace but the major limitation to training trustworthy classifiers is the scarcity of data with ground-truth concept level labels, which are meta-labels semantically meaningful to humans. Foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Soham Gadgil , Mahtab Bigverdi

Multiple Instance Learning (MIL) is the leading approach for whole slide image (WSI) classification, enabling efficient analysis of gigapixel pathology slides. Recent work has introduced vision-language models (VLMs) into MIL pipelines to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Ngoc Bui Lam Quang , Nam Le Nguyen Binh , Thanh-Huy Nguyen , Le Thien Phuc Nguyen , Quan Nguyen , Ulas Bagci

Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

The application of Vision-language foundation models (VLFMs) to remote sensing (RS) imagery has garnered significant attention due to their superior capability in various downstream tasks. A key challenge lies in the scarcity of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Yiguo He , Junjie Zhu , Yiying Li , Xiaoyu Zhang , Chunping Qiu , Jun Wang , Qiangjuan Huang , Ke Yang

Large-scale web-crawled datasets are fundamental for the success of pre-training vision-language models, such as CLIP. However, the inherent noise and potential irrelevance of web-crawled AltTexts pose challenges in achieving precise…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Zhengfeng Lai , Haotian Zhang , Bowen Zhang , Wentao Wu , Haoping Bai , Aleksei Timofeev , Xianzhi Du , Zhe Gan , Jiulong Shan , Chen-Nee Chuah , Yinfei Yang , Meng Cao

CLIP is a seminal multimodal model that maps images and text into a shared representation space through contrastive learning on billions of image-caption pairs. Inspired by the rapid progress of large language models (LLMs), we investigate…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Weiquan Huang , Aoqi Wu , Yifan Yang , Xufang Luo , Yuqing Yang , Usman Naseem , Chunyu Wang , Chunyu Wang , Qi Dai , Xiyang Dai , Dongdong Chen , Chong Luo , Lili Qiu , Liang Hu

Vision-Language Models (VLMs) have recently emerged, demonstrating remarkable vision-understanding capabilities. However, training these models requires large-scale datasets, which brings challenges related to efficiency, effectiveness, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Zheng Liu , Hao Liang , Bozhou Li , Wentao Xiong , Chong Chen , Conghui He , Wentao Zhang , Bin Cui

Vision-Language Models (VLMs) are advancing computational pathology with superior visual understanding capabilities. However, current systems often reduce diagnosis to directly output conclusions without verifiable evidence-linked…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Songhan Jiang , Fengchun Liu , Ziyue Wang , Linghan Cai , Yongbing Zhang

Large-scale but noisy image-text pair data have paved the way for the success of Contrastive Language-Image Pretraining (CLIP). As the foundation vision encoder, CLIP in turn serves as the cornerstone for most large vision-language models…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Zhixiang Wei , Guangting Wang , Xiaoxiao Ma , Ke Mei , Huaian Chen , Yi Jin , Fengyun Rao

Vision language models (VLM) have achieved success in both natural language comprehension and image recognition tasks. However, their use in pathology report generation for whole slide images (WSIs) is still limited due to the huge size of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Jing Wei Tan , SeungKyu Kim , Eunsu Kim , Sung Hak Lee , Sangjeong Ahn , Won-Ki Jeong

The creation of high-quality human-labeled image-caption datasets presents a significant bottleneck in the development of Visual-Language Models (VLMs). In this work, we investigate an approach that leverages the strengths of Large Language…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Sahand Sharifzadeh , Christos Kaplanis , Shreya Pathak , Dharshan Kumaran , Anastasija Ilic , Jovana Mitrovic , Charles Blundell , Andrea Banino

Multimodal learning has shown promise in medical imaging, combining complementary modalities like images and text. Vision-language models (VLMs) capture rich diagnostic cues but often require large paired datasets and prompt- or text-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Banafsheh Karimian , Giulia Avanzato , Soufian Belharbi , Alexis Guichemerre , Luke McCaffrey , Mohammadhadi Shateri , Eric Granger
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