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Related papers: PathGen-1.6M: 1.6 Million Pathology Image-text Pai…

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Vision-language models (VLMs), such as CLIP and ALIGN, are generally trained on datasets consisting of image-caption pairs obtained from the web. However, real-world multimodal datasets, such as healthcare data, are significantly more…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Maya Varma , Jean-Benoit Delbrouck , Sarah Hooper , Akshay Chaudhari , Curtis Langlotz

The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

Whole-slide images (WSIs) in pathology can reach up to 10,000 x 10,000 pixels, posing significant challenges for multimodal large language model (MLLM) due to long context length and high computational demands. Previous methods typically…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Weimin Lyu , Qingqiao Hu , Kehan Qi , Zhan Shi , Wentao Huang , Saumya Gupta , Chao Chen

This paper explores training medical vision-language models (VLMs) -- where the visual and language inputs are embedded into a common space -- with a particular focus on scenarios where training data is limited, as is often the case in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rhydian Windsor , Amir Jamaludin , Timor Kadir , Andrew Zisserman

Vision-language models (VLMs) have the potential to become co-pilots for pathologists. However, most VLMs either focus on small regions of interest within whole-slide images, provide only static slide-level outputs, or rely on data that is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Sander Moonemans , Sebastiaan Ram , Frédérique Meeuwsen , Carlijn Lems , Jeroen van der Laak , Geert Litjens , Francesco Ciompi

Vision-language models are integral to computer vision research, yet many high-performing models remain closed-source, obscuring their data, design and training recipe. The research community has responded by using distillation from…

Effective scaling and a flexible task interface enable large language models to excel at many tasks. We present PaLI (Pathways Language and Image model), a model that extends this approach to the joint modeling of language and vision. PaLI…

The recent large-scale vision-language pre-training (VLP) of dual-stream architectures (e.g., CLIP) with a tremendous amount of image-text pair data, has shown its superiority on various multimodal alignment tasks. Despite its success, the…

Computation and Language · Computer Science 2022-03-31 Wenliang Dai , Lu Hou , Lifeng Shang , Xin Jiang , Qun Liu , Pascale Fung

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Recent accelerations in multi-modal applications have been made possible with the plethora of image and text data available online. However, the scarcity of analogous data in the medical field, specifically in histopathology, has slowed…

Despite the progress made by multimodal large language models (MLLMs) in computational pathology, they remain limited by a predominant focus on patch-level analysis, missing essential contextual information at the whole-slide level. The…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Ying Chen , Guoan Wang , Yuanfeng Ji , Yanjun Li , Jin Ye , Tianbin Li , Ming Hu , Rongshan Yu , Yu Qiao , Junjun He

Medical vision language pre-training (VLP) has emerged as a frontier of research, enabling zero-shot pathological recognition by comparing the query image with the textual descriptions for each disease. Due to the complex semantics of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Vu Minh Hieu Phan , Yutong Xie , Yuankai Qi , Lingqiao Liu , Liyang Liu , Bowen Zhang , Zhibin Liao , Qi Wu , Minh-Son To , Johan W. Verjans

The previous advancements in pathology image understanding primarily involved developing models tailored to specific tasks. Recent studies has demonstrated that the large vision-language model can enhance the performance of various…

Artificial Intelligence · Computer Science 2024-08-20 Dawei Dai , Yuanhui Zhang , Long Xu , Qianlan Yang , Xiaojing Shen , Shuyin Xia , Guoyin Wang

Large vision-language models (VLMs), such as CLIP, learn rich joint image-text representations, facilitating advances in numerous downstream tasks, including zero-shot classification and text-to-image generation. Nevertheless, existing VLMs…

Computer Vision and Pattern Recognition · Computer Science 2023-02-24 Roni Paiss , Ariel Ephrat , Omer Tov , Shiran Zada , Inbar Mosseri , Michal Irani , Tali Dekel

Curation methods for massive vision-language datasets trade off between dataset size and quality. However, even the highest quality of available curated captions are far too short to capture the rich visual detail in an image. To show the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Jack Urbanek , Florian Bordes , Pietro Astolfi , Mary Williamson , Vasu Sharma , Adriana Romero-Soriano

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Vision-language models (VLMs) embed aligned image-text pairs into a joint space but often rely on deterministic embeddings, assuming a one-to-one correspondence between images and texts. This oversimplifies real-world relationships, which…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sanghyuk Chun , Wonjae Kim , Song Park , Sangdoo Yun

Vision Language Models (VLMs) have demonstrated significant potential in various downstream tasks, including Image/Video Generation, Visual Question Answering, Multimodal Chatbots, and Video Understanding. However, these models often…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Ahmad Mustafa Anis , Hasnain Ali , Saquib Sarfraz

Pretrained vision-language models (VLMs) such as CLIP excel in general multimodal comprehension but often struggle to capture nuanced, context-dependent visual cues. This makes it difficult to distinguish between similar-looking concepts…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Yuchen Huang , Zhiyuan Fan , Zhitao He , Sandeep Polisetty , Wenyan Li , Yi R. Fung

Vision-Language Models (VLMs) have shown strong performance in zero-shot image classification tasks. However, existing methods, including Contrastive Language-Image Pre-training (CLIP), all rely on annotated text-to-image pairs for aligning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Dianxing Shi , Dingjie Fu , Yuqiao Liu , Jun Wang