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Alzheimer's disease (AD) is a neurodegenerative disorder that is beginning with amyloidosis, followed by neuronal loss and deterioration in structure, function, and cognition. The accumulation of amyloid-beta in the brain, measured through…

Quantitative analysis of vessel wall structures by automated vessel wall segmentation provides useful imaging biomarkers in evaluating atherosclerotic lesions and plaque progression time-efficiently. To quantify vessel wall features,…

Image and Video Processing · Electrical Eng. & Systems 2019-09-06 Li Chen , Jie Sun , Gador Canton , Niranjan Balu , Xihai Zhao , Rui Li , Thomas S. Hatsukami , Jenq-Neng Hwang , Chun Yuan

Accurate polyp segmentation in colonoscopy is essential for cancer prevention but remains challenging due to: (1) high morphological variability (from flat to protruding lesions), (2) strong visual similarity to normal structures such as…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Abdul Joseph Fofanah , Lian Wen , Alpha Alimamy Kamara , Zhongyi Zhang , David Chen , Albert Patrick Sankoh

Graph Neural Networks (GNNs) are widely applied for graph anomaly detection. As one of the key components for GNN design is to select a tailored spectral filter, we take the first step towards analyzing anomalies via the lens of the graph…

Machine Learning · Computer Science 2022-06-01 Jianheng Tang , Jiajin Li , Ziqi Gao , Jia Li

Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…

Machine Learning · Computer Science 2025-09-24 Niharika Tewari , Nguyen Linh Dan Le , Mujie Liu , Jing Ren , Ziqi Xu , Tabinda Sarwar , Veeky Baths , Feng Xia

Glaucoma is one of the most severe eye diseases, characterized by rapid progression and leading to irreversible blindness. It is often the case that diagnostics is carried out when one's sight has already significantly degraded due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ahmed Al Mahrooqi , Dmitrii Medvedev , Rand Muhtaseb , Mohammad Yaqub

The retina is the only part of the human body in which blood vessels can be accessed non-invasively using imaging techniques such as digital fundus images (DFI). The spatial distribution of the retinal microvasculature may change with…

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Diabetic Retinopathy (DR) is a complication of long-standing, unchecked diabetes and one of the leading causes of blindness in the world. This paper focuses on improved and robust methods to extract some of the features of DR, viz. Blood…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Soham Basu , Sayantan Mukherjee , Ankit Bhattacharya , Anindya Sen

Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…

Tissues and Organs · Quantitative Biology 2023-03-24 Jennifer Buoncore , Alexis Sobecki , Brian Lee Beatty

Coronary artery disease (CAD) remains a prevalent cardiovascular condition, posing significant health risks worldwide. This pathology, characterized by plaque accumulation in coronary artery walls, leads to myocardial ischemia and various…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Xinyun Liu , Chen Zhao

A stroke occurs when an artery in the brain ruptures and bleeds or when the blood supply to the brain is cut off. Blood and oxygen cannot reach the brain's tissues due to the rupture or obstruction resulting in tissue death. The Middle…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Ujjwal Upadhyay , Mukul Ranjan , Satish Golla , Swetha Tanamala , Preetham Sreenivas , Sasank Chilamkurthy , Jeyaraj Pandian , Jason Tarpley

Stroke is the second most frequent cause of death worldwide with a considerable economic burden on the health systems. In about 15% of strokes, atherosclerotic carotid plaques (ACPs) constitute the main etiological factor. Early detection…

Computer Vision and Pattern Recognition · Computer Science 2018-08-27 Lazar Kats , Marilena Vered , Ayelet Zlotogorski-Hurvitz , Itai Harpaz

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Medical image segmentation can provide detailed information for clinical analysis which can be useful for scenarios where the detailed location of a finding is important. Knowing the location of disease can play a vital role in treatment…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Abhishek Srivastava , Sukalpa Chanda , Debesh Jha , Michael A. Riegler , Pål Halvorsen , Dag Johansen , Umapada Pal

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, with blood pressure serving as a crucial indicator. Arterial blood pressure (ABP) waveforms provide continuous pressure measurements throughout the cardiac cycle and…

Machine Learning · Computer Science 2024-03-01 Lingfeng Li , Xue-Cheng Tai , Raymond Chan

Accurate 3D brain MRI subtype classification benefits from both localized anatomical cues and long-range contextual reasoning. We present AGA3DNet, a report-grounded framework that incorporates brief anatomical phrases extracted from…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Peiyu Duan , Xueqi Guo , Sepehr Farhand , Mehmet Berk Sahin , Xinyuan Zheng , James S. Duncan , Gerardo Hermosillo Valadez , Yoshihisa Shinagawa

Breast lesions segmentation is an important step of computer-aided diagnosis system, and it has attracted much attention. However, accurate segmentation of malignant breast lesions is a challenging task due to the effects of heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2022-04-29 Gongping Chen , Yuming Liu , Yu Dai , Jianxun Zhang , Liang Cui , Xiaotao Yin

Medical image analysis for complex tasks such as severity grading and disease subtype classification poses significant challenges due to intricate and similar visual patterns among classes, scarcity of labeled data, and variability in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ansh Makwe , Akansh Agrawal , Prateek Jain , Akshan Agrawal , Priyanka Bagade

The shape and motion of the heart provide essential clues to understanding the mechanisms of cardiovascular disease. With the advent of large-scale cardiac imaging data, statistical atlases become a powerful tool to provide automated and…