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Three-photon (3P) microscopy is getting traction due to its superior performance in deep tissues. Yet, aberrations and light scattering still pose one of the main limitations in the attainable depth ranges for high-resolution imaging. Here,…

The increasing complexity of neural networks and the energy consumption associated with training and inference create a need for alternative neuromorphic approaches, e.g. using optics. Current proposals and implementations rely on physical…

Optics · Physics 2023-08-31 Clara C. Wanjura , Florian Marquardt

Nonlinear optical microscopy allows rapid high-resolution microscopy with image contrast generated from intrinsic properties of the sample. Established modalities such as multiphoton excited fluorescence and second/third-harmonic generation…

Two-photon microscopy is a powerful tool for in vivo imaging, but its imaging depth is typically limited to a few hundred microns due to tissue scattering, even with existing scattering correction techniques. Moreover, most active…

Optics · Physics 2025-05-29 Renzhi He , Yucheng Li , Brianna Urbina , Jiandi Wan , Yi Xue

Thick biological tissues give rise to not only the scattering of incoming light waves, but also aberrations of the remaining unscattered waves. Due to the inability of existing optical imaging methodologies to overcome both of these…

Consider the scattering of a time-harmonic plane wave by heterogeneous media consisting of linear or nonlinear point scatterers and extended obstacles. A generalized Foldy-Lax formulation is developed to take fully into account of the…

Numerical Analysis · Mathematics 2017-06-22 Jun Lai , Ming Li , Peijun Li , Wei Li

Multi-photon microscopy is a powerful technique for deep-tissue imaging, providing high spatial resolution at increased penetration depth. Nevertheless, imaging remains largely restricted to superficial tissue layers well below 1 mm.…

Empowered by deep learning, recent methods for material capture can estimate a spatially-varying reflectance from a single photograph. Such lightweight capture is in stark contrast with the tens or hundreds of pictures required by…

Graphics · Computer Science 2019-06-28 Valentin Deschaintre , Miika Aittala , Fredo Durand , George Drettakis , Adrien Bousseau

Nonlinear optics is essential for many recent photonic technologies. Here, we introduce a novel multi-scale approach to simulate the nonlinear optical response of molecular nanomaterials combining ab initio quantum-chemical and classical…

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…

We develop a multiexposure image fusion method based on texture features, which exploits the edge preserving and intraregion smoothing property of nonlinear diffusion filters based on partial differential equations (PDE). With the captured…

Multimedia · Computer Science 2013-07-11 Harbinder Singh , Vinay Kumar , Sunil Bhooshan

Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast to hemoglobin oxidization level. However, due to the complicated non-linear photon…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Jaejun Yoo , Sohail Sabir , Duchang Heo , Kee Hyun Kim , Abdul Wahab , Yoonseok Choi , Seul-I Lee , Eun Young Chae , Hak Hee Kim , Young Min Bae , Young-wook Choi , Seungryong Cho , Jong Chul Ye

High-resolution optical microscopy has transformed biological imaging, yet its resolution and contrast deteriorate with depth due to multiple light scattering. Conventional correction strategies typically approximate the medium as one or a…

While scattered light conveys most of the information we perceive, scattering may also distort that information before it reaches our detectors. The problem is acute in many applications, such as in high-resolution microscopy of biological…

Recently an optical amplification process called the plasmon injection scheme was introduced as an effective solution to overcoming losses in metamaterials. Implementations with near-field imaging applications have indicated substantial…

Optics · Physics 2020-08-26 Anindya Ghoshroy , Wyatt Adams , Durdu O. Guney

We propose a method of complex-amplitude Fourier single-pixel imaging (CFSI) with coherent structured illumination to acquire both the amplitude and phase of an object. In the proposed method, an object is illustrated by a series of…

On-invasive optical imaging techniques are essential diagnostic tools in many fields. Although various recent methods have been proposed to utilize and control light in multiple scattering media, non-invasive optical imaging through and…

The problem of reconstructing an object from the measurements of the light it scatters is common in numerous imaging applications. While the most popular formulations of the problem are based on linearizing the object-light relationship,…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Yanting Ma , Hassan Mansour , Dehong Liu , Petros T. Boufounos , Ulugbek S. Kamilov

Non-invasive and single-shot holographic imaging through complex media is technically challenging due to random light scattering which significantly scrambles optical information. Recently, several methods have been presented to address…

Phase is a fundamental resource for optical imaging but cannot be directly observed with intensity measurements. The existing methods to quantify a phase distribution rely on complex devices and structures. Here we experimentally…

Optics · Physics 2020-03-25 Tengfeng Zhu , Junyi Huang , Zhichao Ruan