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Machine learning promises to revolutionize clinical decision making and diagnosis. In medical diagnosis a doctor aims to explain a patient's symptoms by determining the diseases \emph{causing} them. However, existing diagnostic algorithms…

Machine Learning · Statistics 2020-03-17 Jonathan G. Richens , Ciaran M. Lee , Saurabh Johri

Artificial intelligence (AI) systems power the world we live in. Deep neural networks (DNNs) are able to solve tasks in an ever-expanding landscape of scenarios, but our eagerness to apply these powerful models leads us to focus on their…

Computer Vision and Pattern Recognition · Computer Science 2022-04-22 Loris Giulivi , Mark James Carman , Giacomo Boracchi

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Algorithms based on deep network models are being used for many pattern recognition and decision-making tasks in robotics and AI. Training these models requires a large labeled dataset and considerable computational resources, which are not…

Artificial Intelligence · Computer Science 2022-01-26 Mohan Sridharan , Tiago Mota

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

There has been a growing interest in model-agnostic methods that can make deep learning models more transparent and explainable to a user. Some researchers recently argued that for a machine to achieve a certain degree of human-level…

Artificial Intelligence · Computer Science 2021-06-09 Yu-Liang Chou , Catarina Moreira , Peter Bruza , Chun Ouyang , Joaquim Jorge

Research around AI for Science has seen significant success since the rise of deep learning models over the past decade, even with longstanding challenges such as protein structure prediction. However, this fast development inevitably made…

Artificial Intelligence · Computer Science 2022-12-27 Kieran Didi , Matej Zečević

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

Machines are being increasingly used in decision-making processes, resulting in the realization that decisions need explanations. Unfortunately, an increasing number of these deployed models are of a 'black-box' nature where the reasoning…

Artificial Intelligence · Computer Science 2023-11-07 Sopam Dasgupta

We propose a BlackBox Counterfactual Explainer, designed to explain image classification models for medical applications. Classical approaches (e.g., saliency maps) that assess feature importance do not explain "how" imaging features in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Sumedha Singla , Motahhare Eslami , Brian Pollack , Stephen Wallace , Kayhan Batmanghelich

Medical image segmentation plays a vital role in clinical decision-making, enabling precise localization of lesions and guiding interventions. Despite significant advances in segmentation accuracy, the black-box nature of most deep models…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Limai Jiang , Ruitao Xie , Bokai Yang , Huazhen Huang , Juan He , Yufu Huo , Zikai Wang , Yang Wei , Yunpeng Cai

Concept-based explanation approach is a popular model interpertability tool because it expresses the reasons for a model's predictions in terms of concepts that are meaningful for the domain experts. In this work, we study the problem of…

Machine Learning · Computer Science 2021-05-25 Mohammad Taha Bahadori , David E. Heckerman

While multimodal large language models offer a promising solution to the "black box" nature of health AI by generating interpretable reasoning traces, verifying the validity of these traces remains a critical challenge. Existing evaluation…

Current approaches to explaining the decisions of deep learning systems for medical tasks have focused on visualising the elements that have contributed to each decision. We argue that such approaches are not enough to "open the black box"…

Artificial Intelligence · Computer Science 2018-06-04 William Gale , Luke Oakden-Rayner , Gustavo Carneiro , Andrew P Bradley , Lyle J Palmer

A variety of methods exist to explain image classification models. However, whether they provide any benefit to users over simply comparing various inputs and the model's respective predictions remains unclear. We conducted a user study…

Machine Learning · Computer Science 2022-04-26 Leon Sixt , Martin Schuessler , Oana-Iuliana Popescu , Philipp Weiß , Tim Landgraf

The ambiguity of the decision-making process has been pointed out as the main obstacle to applying the deep learning-based method in a practical way in spite of its outstanding performance. Interpretability could guarantee the confidence of…

Computer Vision and Pattern Recognition · Computer Science 2019-06-11 Hyebin Lee , Seong Tae Kim , Yong Man Ro

Model explanations such as saliency maps can improve user trust in AI by highlighting important features for a prediction. However, these become distorted and misleading when explaining predictions of images that are subject to systematic…

Human-Computer Interaction · Computer Science 2022-03-02 Wencan Zhang , Mariella Dimiccoli , Brian Y. Lim

Deep learning methods for ophthalmic diagnosis have shown considerable success in tasks like segmentation and classification. However, their widespread application is limited due to the models being opaque and vulnerable to making a wrong…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Amitojdeep Singh , Sourya Sengupta , Mohammed Abdul Rasheed , Varadharajan Jayakumar , Vasudevan Lakshminarayanan

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans
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