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Computational models that accurately predict the binding affinity of an input protein-chemical pair can accelerate drug discovery studies. These models are trained on available protein-chemical interaction datasets, which may contain…

Quantitative Methods · Quantitative Biology 2023-01-10 Rıza Özçelik , Alperen Bağ , Berk Atıl , Melih Barsbey , Arzucan Özgür , Elif Özkırımlı

Test-Time Adaptation (TTA) has emerged as a promising solution for adapting a source model to unseen medical sites using unlabeled test data, due to the high cost of data annotation. Existing TTA methods consider scenarios where data from…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 Wei Li , Jingyang Zhang , Lihao Liu , Guoan Wang , Junjun He , Yang Chen , Lixu Gu

Despite the promise of Convolutional neural network (CNN) based classification models for histopathological images, it is infeasible to quantify its uncertainties. Moreover, CNNs may suffer from overfitting when the data is biased. We show…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Ponkrshnan Thiagarajan , Pushkar Khairnar , Susanta Ghosh

Continual test-time adaptation (cTTA) methods are designed to facilitate the continual adaptation of models to dynamically changing real-world environments where computational resources are limited. Due to this inherent limitation, existing…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Younggeol Cho , Youngrae Kim , Dongman Lee

Encountering shifted data at test time is a ubiquitous challenge when deploying predictive models. Test-time adaptation (TTA) methods address this issue by continuously adapting a deployed model using only unlabeled test data. While TTA can…

Machine Learning · Computer Science 2025-11-11 Mona Schirmer , Metod Jazbec , Christian A. Naesseth , Eric Nalisnick

Image-to-image translation has emerged as a powerful technique in medical imaging, enabling tasks such as image denoising and cross-modality conversion. However, it suffers from limitations in handling out-of-distribution samples without…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Irene Iele , Francesco Di Feola , Valerio Guarrasi , Paolo Soda

Although highly accurate automated diagnostic techniques for melanoma have been reported, the realization of a system capable of providing diagnostic evidence based on medical indices remains an open issue because of difficulties in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Kasumi Obi , Quan Huu Cap , Noriko Umegaki-Arao , Masaru Tanaka , Hitoshi Iyatomi

Data augmentation has been actively studied for robust neural networks. Most of the recent data augmentation methods focus on augmenting datasets during the training phase. At the testing phase, simple transformations are still widely used…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 Ildoo Kim , Younghoon Kim , Sungwoong Kim

Deep neural networks are known to be vulnerable to unseen data: they may wrongly assign high confidence stcores to out-distribuion samples. Recent works try to solve the problem using representation learning methods and specific metrics. In…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Haowei He , Jiaye Teng , Yang Yuan

Machine learning models for text classification often excel on in-distribution (ID) data but struggle with unseen out-of-distribution (OOD) inputs. Most techniques for improving OOD robustness are not applicable to settings where the model…

Machine Learning · Computer Science 2024-08-06 Kyle O'Brien , Nathan Ng , Isha Puri , Jorge Mendez , Hamid Palangi , Yoon Kim , Marzyeh Ghassemi , Thomas Hartvigsen

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

\textit{Objectives}: Data scarcity and domain shifts lead to biased training sets that do not accurately represent deployment conditions. A related practical problem is cross-modal image segmentation, where the objective is to segment…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Guillaume Sallé , Pierre-Henri Conze , Julien Bert , Nicolas Boussion , Dimitris Visvikis , Vincent Jaouen

Data Augmentation (DA) has become an essential tool to improve robustness and generalization of modern machine learning. However, when deciding on DA strategies it is critical to choose parameters carefully, and this can be a daunting task…

Machine Learning · Computer Science 2026-03-04 Madi Matymov , Ba-Hien Tran , Michael Kampffmeyer , Markus Heinonen , Maurizio Filippone

Current test-time adaptation (TTA) approaches aim to adapt a machine learning model to environments that change continuously. Yet, it is unclear whether TTA methods can maintain their adaptability over prolonged periods. To answer this…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Trung-Hieu Hoang , Duc Minh Vo , Minh N. Do

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Data Augmentation (DA) -- enriching training data by adding synthetic samples -- is a technique widely adopted in Computer Vision (CV) and Natural Language Processing (NLP) tasks to improve models performance. Yet, DA has struggled to gain…

Machine Learning · Computer Science 2024-01-24 Chao Wang , Alessandro Finamore , Pietro Michiardi , Massimo Gallo , Dario Rossi

With the rapid increase in volume of time series medical data available through wearable devices, there is a need to employ automated algorithms to label data. Examples of labels include interventions, changes in activity (e.g. sleep) and…

Machine Learning · Computer Science 2015-06-16 Tingting Zhu , Nic Dunkley , Joachim Behar , David A. Clifton , Gari D. Clifford

Data augmentation (DA) turns seemingly intractable computational problems into simple ones by augmenting latent missing data. In addition to computational simplicity, it is now well-established that DA equipped with a deterministic…

Methodology · Statistics 2020-05-26 Hyungsuk Tak , Kisung You , Sujit K. Ghosh , Bingyue Su , Joseph Kelly

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

In recent years, one of the most popular techniques in the computer vision community has been the deep learning technique. As a data-driven technique, deep model requires enormous amounts of accurately labelled training data, which is often…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Zihan Yang , Richard O. Sinnott , James Bailey , Qiuhong Ke
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