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While several Gaussian mixture models-based biclustering approaches currently exist in the literature for continuous data, approaches to handle discrete data have not been well researched. A multivariate Poisson-lognormal (MPLN) model-based…
Many real-world networks known as attributed networks contain two types of information: topology information and node attributes. It is a challenging task on how to use these two types of information to explore structural regularities. In…
Generalized linear and additive models are very efficient regression tools but the selection of relevant terms becomes difficult if higher order interactions are needed. In contrast, tree-based methods also known as recursive partitioning…
Positive-Unlabeled (PU) Learning is a challenge presented by binary classification problems where there is an abundance of unlabeled data along with a small number of positive data instances, which can be used to address chronic disease…
Recent work on the problem of latent tree learning has made it possible to train neural networks that learn to both parse a sentence and use the resulting parse to interpret the sentence, all without exposure to ground-truth parse trees at…
Learning causal relationships from empirical observations is a central task in scientific research. A common method is to employ structural causal models that postulate noisy functional relations among a set of interacting variables. To…
A learning algorithm is presented which given the structure of a causal tree, will estimate its link probabilities by sequential measurements on the leaves only. Internal nodes of the tree represent conceptual (hidden) variables…
This paper considers the problem of invoking auxiliary, unobservable variables to facilitate the structuring of causal tree models for a given set of continuous variables. Paralleling the treatment of bi-valued variables in [Pearl 1986], we…
Topic models are widely used for discovering latent thematic structures in large text corpora, yet traditional unsupervised methods often struggle to align with pre-defined conceptual domains. This paper introduces seeded Poisson…
Structural information of phylogenetic tree topologies plays an important role in phylogenetic inference. However, finding appropriate topological structures for specific phylogenetic inference tasks often requires significant design effort…
For a model of molecular evolution to be useful for phylogenetic inference, the topology of evolutionary trees must be identifiable. That is, from a joint distribution the model predicts, it must be possible to recover the tree parameter.…
Training a Named Entity Recognition (NER) model often involves fixing a taxonomy of entity types. However, requirements evolve and we might need the NER model to recognize additional entity types. A simple approach is to re-annotate entire…
Inference of species networks from genomic data under the Network Multispecies Coalescent Model is currently severely limited by heavy computational demands. It also remains unclear how complicated networks can be for consistent inference…
Tree structures appear in many fields of the life sciences, including phylogenetics, developmental biology and nucleic acid structures. Trees can be used to represent RNA secondary structures, which directly relate to the function of…
Named entity recognition (NER), which focuses on the extraction of semantically meaningful named entities and their semantic classes from text, serves as an indispensable component for several down-stream natural language processing (NLP)…
Prompt learning has become a prevalent strategy for adapting vision-language foundation models to downstream tasks. As large language models (LLMs) have emerged, recent studies have explored the use of category-related descriptions as input…
The increasing complexity of data requires methods and models that can effectively handle intricate structures, as simplifying them would result in loss of information. While several analytical tools have been developed to work with complex…
Probability estimation is one of the fundamental tasks in statistics and machine learning. However, standard methods for probability estimation on discrete objects do not handle object structure in a satisfactory manner. In this paper, we…
Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…
Gene regulatory network inference is crucial for understanding the complex molecular interactions in various genetic and environmental conditions. The rapid development of single-cell RNA sequencing (scRNA-seq) technologies unprecedentedly…