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Accurate detection and characterization of nanoparticles within confined spaces is crucial for applications ranging from nanofluidics to biotechnology. We present a novel approach that combines interferometric scattering (iSCAT) detection…

Engineered electromagnetic fields in plasmonic nanopores enable enhanced optical detection and their use in single molecule sequencing. Here, a plasmonic nanopore prepared in a thick nanoporous film is used to investigate the interaction…

Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…

Biological Physics · Physics 2024-11-26 Jie Liao , Maxwell Adolphson , Hangyue Li , Dipayon Kumar Sikder , Chenyang Lu , Lan Yang

This work explores the use of Surface-Enhanced Raman Spectroscopy (SERS) combined with artificial neural network (ANN) models to detect and quantify growth hormone (GH) and testosterone (TE) in the blood of Sprague Dawley (SD) rats. SERS…

We present a microscopic model for surface-enhanced Raman scattering (SERS) from molecules adsorbed on small noble-metal nanoparticles. In the absence of direct overlap of molecular orbitals and electronic states in the metal, the main…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Vitaliy N. Pustovit , Tigran V. Shahbazyan

Nanoparticle metrology has long been constrained by the assumption that, in mixed and unprocessed fluids, particle size, morphology, composition, and species-specific abundance cannot be resolved simultaneously from a single label-free…

Absorption efficiency profiles and localized surface plasmon resonance (LSPR) wavelengths are reported for metallic core-shell nanoparticles (NPs) placed over a BK7 glass substrate. A numerical study is performed with the vectorized version…

Optics · Physics 2020-01-08 Dilan Avsar , Hakan Erturk , M. Pinar Menguc

Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the…

Applied Physics · Physics 2017-08-02 Ozlem Yavas , Mikael Svedendahl , Paulina Dobosz , Vanesa Sanz , Romain Quidant

The characterisation of the physical properties of nanoparticles in their native environment plays a central role in a wide range of fields, from nanoparticle-enhanced drug delivery to environmental nanopollution assessment. Standard…

This research describes the use of surface-enhanced Raman spectroscopy (SERS) substrates based on colloidal silver nanoparticles (AgNPs) produced by laser ablation of silver granules in pure water that are inexpensive, easy to make, and…

Optics · Physics 2023-04-26 A. M. Ondieki , Z. Birech , K. A. Kaduki , P. W. Mwangi

We have synthesized MoS$_{2}$ incorporated $\alpha$-Fe$_{2}$O$_{3}$/ZnO nanocomposites by the hydrothermal process. The effect of incorporating ultrasonically exfoliated MoS$_{2}$ on the photocatalytic performance of…

Applied Physics · Physics 2021-11-16 Angkita Mistry Tama , Subrata Das , Sagar Dutta , M. D. I. Bhuyan , M. N. Islam , M. A. Basith

Thin-wall metal ultramicro- and nanoelectrodes (UMEs/NEs), especially gold NEs, are indispensable for high-resolution electrochemical microscopy, biosensing, and fundamental research. However, their damage susceptibility and the lack of…

Recently, studies have been carried out on attempts to combine surface-enhanced Surface-enhanced Raman spectroscopy (SERS) substrates that can be based on either localized surface plasmon (LSP) or surface plasmon polaritons (SPP)…

Materials Science · Physics 2020-04-22 Samir Kumar , Yusuke Doi , Kyoko Namura , Motofumi Suzuki

Optical fiber-based platforms are increasingly explored as compact, minimally invasive tools for integrated photonic functionalities in biomedical applications. Among these, the combination of plasmonic heating and optical sensing on a…

We present experimental demonstration of a recently predicted path interference phenomenon [Nanophotonics 7, 1687 (2018)]. A SERS process becomes resonant when both incident and the converted frequencies match with two plasmon resonances --…

Semiconductor-based surface-enhanced Raman spectroscopy (SERS) substrates, as a new frontier in the field of SERS, are hindered by their poor electromagnetic field confinement, and weak light-matter interaction. Metasurfaces, a class of 2D…

Oxygen (O2)-sensing matrices are promising tools for the live monitoring of extracellular O2 consumption levels in long-term cell cultures. In this study, ratiometric O2-sensing membranes were prepared by electrospinning, an easy, low-cost,…

We present a simulation guided design for a multilayer surface plasmon resonance (SPR) based biosensor capable of detecting refractive index changes in a target induced by analytes. Surface plasmons are excited using a hybrid Kretschmann…

Optics · Physics 2025-12-23 R. Runthala , V. K. Venkatesh , D. Gupta , P. Arora

Coherent anti-Stokes Raman scattering (CARS) and, in particular, femtosecond adaptive spectroscopic techniques (FAST CARS) have been successfully used for molecular spectroscopy and microscopic imaging. Recent progress in ultrafast…

Label-free single-molecule detection is essential for studying biomolecules in their native state, yet having materials with intrinsic molecular specificity to identify a broad range of molecules without complex functionalization remains…

Mesoscale and Nanoscale Physics · Physics 2024-09-30 Miao Zhang , Cristina Izquierdo Lozano , Stijn van Veen , Lorenzo Albertazzi