Related papers: Highly Sensitive Label-free Biomolecular Detection…
An approach to significantly enhance spontaneous Raman sensitivity through the formation of a thin film via thermophoresis along with evaporation at the facet of a Hollow-Core Photonic Crystal Fiber is reported for the first time.…
In analogy to cavity optomechanics, enhancing specific sidebands of a Raman process with narrowband optical resonators would allow for parametric amplification, entanglement of light and molecular vibrations, and reduced transduction noise.…
Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting…
Terahertz time-domain spectroscopy (THz-TDS) is a non-invasive, non-contact and label-free technique for biological and chemical sensing as THz-spectra is less energetic and lies in the characteristic vibration frequency regime of proteins…
The dependence of surface-enhanced Raman scattering (SERS) spectra on the precise axial position of the laser focus relative to a solid nanostructured substrate has received little to no attention in the literature. Here we show this…
Single-molecule detection with chemical specificity is a powerful and much desired tool for biology, chemistry, physics, and sensing technologies. Surface-enhanced spectroscopies enable single molecule studies, yet reliable substrates of…
Biosensing based on whispering-gallery mode (WGM) resonators has been continuously studied with great attention due to its excellent sensitivity guaranteeing the label-free detection. However, its practical impact is insignificant to date…
In this article, tip-enhanced Raman spectroscopy (TERS) is investigated as a precise method for analysis of biological samples. Using Finite Difference Time Domain (FDTD) simulation, it has been tried to design the required structures for…
Histochemical staining is essential for visualizing tissue architecture and cellular morphology but is destructive and limited by the availability of tissue for multiple stains. Virtual staining with label-free microscopy offers a…
It is an established understanding that the electromagnetic contribution (the plasmon-mediated enhancement of the laser and scattered local electromagnetic fields) is the main actor in Surface Enhanced Raman Scattering (SERS), with the…
Epitaxially grown InAs NWs are relevant for electrical sensing applications due to Fermi level pinning at NW surface, thus very sensitive to surrounding environment. While a single NW growth batch consists of millions virtually identical…
We have developed an efficient numerical method to investigate light scattering from plasmonic nanospheres on a substrate covered by a shell, based on the half-space Greens function approach. We use this method to study optical scattering…
Optical fiber sensing carries a number of potential advantages for diagnostics and biomarker detection and monitoring, yet particular challenges persist in linking molecular recognition events to a change in the refractive index. DNA…
Here we show how surface-enhanced Raman spectroscopy (SERS) features can be fine-tuned in optically active substrates made of layered materials. To demonstrate this, we used DNA-assisted lithography (DALI) to create substrates with silver…
We have demonstrated atomically thin, quantum capacitance-limited, field-effect transistors (FETs) that enable the detection of pH changes with ~75-fold higher sensitivity (4.4 V/pH) over the Nernst value of 59 mV/pH at room temperature…
Plasmonic materials have got wide attention as a potential candidate for light driven catalysis of chemical conversions by harnessing solar energy to reduce the environmental issues generated by fossil fuels-based bulk chemical industries.…
Ag nanorod arrays/dielectrics/mirror-structured multilayer thin-film are well known, highly sensitive surface-enhanced Raman scattering (SERS) substrates that enhance the Raman scattering cross-section by the interference of light. However,…
Large scale simulations are performed by means of the transfer-matrix method to reveal optimal conditions for metal-dielectric core-shell particles to induce the largest fluorescence on their surfaces. With commonly used plasmonic cores (Au…
The experimental limitations in the signal enhancement and spatial resolution in spectroscopic imaging have been always a challenging task in the application of near-field spectroscopy for nanostructured materials in the sub-diffraction…
Sensitive biomarker detection in physiological fluids is often limited by Debye screening, which suppresses electrostatic signals at sensor surfaces. Here we report a sensing approach based on flexoelectric resonance in silicon nanowire…