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Chiral nanophotonic platforms provide a means of creating near fields with both enhanced asymmetric properties and intensities. They can be exploited for optical measurements that allow enantiomeric discrimination at detection levels…

Label-free biosensors are important tools for clinical diagnostics and for studying biology at the single molecule level. The development of optical label-free sensors has allowed extreme sensitivity, but can expose the biological sample to…

This work presents a high-performance, multilayered surface plasmon resonance (SPR)-based sensor designed to enhance performance parameters in the near-infrared (NIR) region through angular interrogation. The multi-layered sensor consists…

Optics · Physics 2025-11-11 R. Runthala , N. Grover , P. Arora

Simple methods to detect biomolecules including specific nucleic acid sequences have received renewed attention since the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus pandemic. Notably, biomolecule detection that uses…

Biomolecules · Quantitative Biology 2024-09-09 A. A. Aldakheel , C. B. Raub , H. T. Bui

The Raman scattering of light by molecular vibrations offers a powerful technique to 'fingerprint' molecules via their internal bonds and symmetries. Since Raman scattering is weak, methods to enhance, direct and harness it are highly…

Plasmon-free surface-enhanced Raman scattering (SERS) substrates have attracted tremendous attention for their abundant sources, excellent chemical stability, superior biocompatibility, good signal uniformity, and unique selectivity to…

Optics · Physics 2021-06-10 Leilei Lan , Yimeng Gao , Xingce Fan , Mingze Li , Qi Hao , Teng Qiu

Even after more than four decades of rapid-pace advances, the adoption of Surface-Enhanced Raman Scattering (SERS) remains limited, due to the difficulties in fabrication of effective and affordable nanostructured surfaces or templates.…

Plasmonic nanostructures have wide applications in photonics including pathogen detection and diagnosis via Surface-Enhanced Raman Spectroscopy (SERS). Despite major role plasmonics play in signal enhancement, electrostatics in SERS is yet…

Cell Behavior · Quantitative Biology 2025-01-22 Jia Dong , Jeong Hee Kim , Isaac Pincus , Sujan Manna , Jennifer M. Podgorski , Yanmin Zhu , Loza F. Tadesse

Anisotropic Au nanoparticles show unique localized surface plasmon resonance (LSPR) properties, which make it attractive in optical, sensing, and biomedical applications. In this contribution, we report a general and facile strategy towards…

Chemical Physics · Physics 2015-01-06 Jingshan Du , Junjie Yu , Yalin Xiong , Zhuoqing Lin , Hui Zhang , Deren Yang

Electromagnetic theory predicts that the optimal value of the localized plasmon resonance (LPR) wavelength for the maximal SERS enhancement factor (EF) is half the sum of the laser and Raman wavelengths. For small Raman shifts, the…

Creating plasmonic nanoparticles on a tapered optical fiber tip enables a remote SERS sensing probe, ideal for challenging sampling scenarios like biological tissue, specific cells, on-site environmental monitoring, and deep brain…

This work demonstrates an original and ultrasensitive approach for surface-enhanced Raman spectroscopy (SERS) detection based on evaporation of self-lubricating drops containing silver supraparticles. The developed method detects an…

The last two decades have witnessed a dramatic growth of wearable sensor technology, mainly represented by flexible, stretchable, on-skin electronic sensors that provide rich information of the wearer's health conditions and surroundings. A…

The incorporation of plasmonic metal nanostructures into semiconducting chalcogenides, in the form of core-shell structures, represents a promising approach to boosting the performance of photodetectors. In this study, we combined Au…

The electromagnetic enhancement for surface enhanced Raman spectroscopy (SERS) of graphene is studied by inserting a layer of Al2O3 between epitaxial graphene and Au nanoparticles. Different excitation lasers are utilized to study the…

Surface-enhanced Raman spectroscopy (SERS) allows single-molecule detection due to the strong field localization occurring at sharp bends or kinks of the metal-vacuum interface. An important question concerns the limits of the signal…

Optics · Physics 2008-06-19 Sanshui Xiao , Niels Asger Mortensen , Antti-Pekka Jauho

We proposed an extremely sensitive \textit{E. Coli} sensor based on a hyperbolic metamaterial structure combining ultra-thin Ag-Al$_2$O$_3$ layers to minimize metallic optical loss. The principle relied on detecting the change in the…

Optics · Physics 2023-11-29 Dip Sarker , Ahmed Zubair

There is an urgent need for the development of novel and truly rapid (equal or less than 1 hour) antibiotic susceptibility testing (AST) platforms in order to provide best antimicrobial prescribing practices and to help reduce the…

Subcellular Processes · Quantitative Biology 2025-01-22 Allen Fraiman , Lawrence Ziegler

Strain-level identification of viruses is critical for effective public health responses to potential outbreaks, yet current diagnostic methods often lack the necessary speed or sensitivity. Surface-enhanced Raman spectroscopy (SERS) offers…

Plasmon-enhanced chemical transformations at the solid-liquid interface can be imaged with high sensitivity, chemical selectivity, and nanoscale precision through tip-enhanced Raman scattering (TERS). We demonstrate the latter for the first…

Chemical Physics · Physics 2019-03-29 Ashish Bhattarai , Patrick Z. El-Khoury