English
Related papers

Related papers: Biomedical Visual Instruction Tuning with Clinicia…

200 papers

Multi-modal large language models (MLLMs) are expected to support multi-turn queries of interchanging image and text modalities in production. However, the current MLLMs trained with visual-question-answering (VQA) datasets could suffer…

Computation and Language · Computer Science 2024-11-06 Shengzhi Li , Rongyu Lin , Shichao Pei

The rapid expansion of electronic health record (EHR) systems has generated large volumes of unstructured clinical narratives that contain valuable information for disease identification, patient cohort discovery, and clinical decision…

Computation and Language · Computer Science 2026-03-17 Fariba Afrin Irany , Sampson Akwafuo

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Instruction-finetuning (IFT) has become crucial in aligning Large Language Models (LLMs) with diverse human needs and has shown great potential in medical applications. However, previous studies mainly fine-tune LLMs on biomedical datasets…

Computation and Language · Computer Science 2025-04-02 Xinlu Zhang , Chenxin Tian , Xianjun Yang , Lichang Chen , Zekun Li , Linda Ruth Petzold

Large vision language models (LVLMs) have demonstrated impressive performance across a wide range of tasks. These capabilities largely stem from visual instruction tuning, which fine-tunes models on datasets consisting of curated…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Myeongkyun Kang , Soopil Kim , Xiaoxiao Li , Sang Hyun Park

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

Medical vision foundation models remain limited in downstream tasks, particularly volumetric medical image segmentation. While fine-tuning on labeled target-domain data improves performance, existing approaches typically rely on randomly…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Jin Yang , Daniel S. Marcus , Aristeidis Sotiras

Large Language Models (LLMs) have demonstrated remarkable capabilities across various domains and are moving towards more specialized areas. Recent advanced proprietary models such as GPT-4 and Gemini have achieved significant advancements…

Computation and Language · Computer Science 2024-10-30 Kaiyan Zhang , Sihang Zeng , Ermo Hua , Ning Ding , Zhang-Ren Chen , Zhiyuan Ma , Haoxin Li , Ganqu Cui , Biqing Qi , Xuekai Zhu , Xingtai Lv , Hu Jinfang , Zhiyuan Liu , Bowen Zhou

The increase in the availability of online videos has transformed the way we access information and knowledge. A growing number of individuals now prefer instructional videos as they offer a series of step-by-step procedures to accomplish…

Computation and Language · Computer Science 2023-09-22 Deepak Gupta , Kush Attal , Dina Demner-Fushman

This study introduces an evaluation framework for multimodal models in medical imaging diagnostics. We developed a pipeline incorporating data preprocessing, model inference, and preference-based evaluation, expanding an initial set of 500…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Cailian Ruan , Chengyue Huang , Yahe Yang

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Existing visual instruction tuning methods typically prompt large language models with textual descriptions to generate instruction-following data. Despite the promising performance achieved, these descriptions are derived from image…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Junke Wang , Lingchen Meng , Zejia Weng , Bo He , Zuxuan Wu , Yu-Gang Jiang

Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 David Restrepo , Ira Ktena , Maria Vakalopoulou , Stergios Christodoulidis , Enzo Ferrante

Clinical decision-making routinely demands reasoning over heterogeneous data, yet existing multimodal language models (MLLMs) remain largely vision-centric and fail to generalize across clinical specialties. To bridge this gap, we introduce…

Machine Learning · Computer Science 2025-10-23 Wei Dai , Peilin Chen , Chanakya Ekbote , Paul Pu Liang

Visual instruction tuning (VIT) datasets have grown rapidly in scale, yet the informativeness of individual training samples has largely been overlooked. Recent dataset selection methods have shown that a small fraction of such datasets…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Xindi Wu , Hee Seung Hwang , Polina Kirichenko , Esin Tureci , Olga Russakovsky

Instruction tuning, a new learning paradigm that fine-tunes pre-trained language models on tasks specified through instructions, has shown promising zero-shot performance on various natural language processing tasks. However, it has yet to…

Computation and Language · Computer Science 2023-06-13 Zhiyang Xu , Ying Shen , Lifu Huang

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Engineering LLMs to accelerate life sciences research requires a robust alignment with biomedical knowledge. We observe that biomedical text exhibits a fundamentally different uncertainty structure from general text: dense low-confidence…

Medical diagnostic applications require models that can process multimodal medical inputs (images, patient histories, lab results) and generate diverse outputs including both textual reports and visual content (annotations, segmentation…