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Auditory and visual signals usually present together and correlate with each other, not only in natural environments but also in clinical settings. However, the audio-visual modelling in the latter case can be more challenging, due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Jianbo Jiao , Mohammad Alsharid , Lior Drukker , Aris T. Papageorghiou , Andrew Zisserman , J. Alison Noble

Determining causal effects of interventions onto outcomes from real-world, observational (non-randomized) data, e.g., treatment repurposing using electronic health records, is challenging due to underlying bias. Causal deep learning has…

Machine Learning · Computer Science 2025-10-23 Shantanu Ghosh , Zheng Feng , Jiang Bian , Kevin Butler , Mattia Prosperi

Multimodal recommendation aims to enhance user preference modeling by leveraging rich item content such as images and text. Yet dominant systems fuse modalities in the spatial domain, obscuring the frequency structure of signals and…

Information Retrieval · Computer Science 2026-02-02 Wei Yang , Rui Zhong , Yiqun Chen , Shixuan Li , Heng Ping , Chi Lu , Peng Jiang

Machine learning-aided clinical decision support has the potential to significantly improve patient care. However, existing efforts in this domain for principled quantification of uncertainty have largely been limited to applications of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 L. Julian Lechuga Lopez , Tim G. J. Rudner , Farah E. Shamout

We propose L2T, an advancement of visual instruction tuning (VIT). While VIT equips Multimodal LLMs (MLLMs) with promising multimodal capabilities, the current design choices for VIT often result in overfitting and shortcut learning,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Zhihan Zhou , Feng Hong , Jiaan Luo , Jiangchao Yao , Dongsheng Li , Bo Han , Ya Zhang , Yanfeng Wang

Aligning Large Language Models (LLMs) with high-stakes medical standards remains a significant challenge, primarily due to the dissonance between coarse-grained preference signals and the complex, multi-dimensional nature of clinical…

Artificial Intelligence · Computer Science 2026-04-10 He Geng , Yangmin Huang , Lixian Lai , Qianyun Du , Hui Chu , Zhiyang He , Jiaxue Hu , Xiaodong Tao

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Multimodal learning has shown promise in medical imaging, combining complementary modalities like images and text. Vision-language models (VLMs) capture rich diagnostic cues but often require large paired datasets and prompt- or text-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Banafsheh Karimian , Giulia Avanzato , Soufian Belharbi , Alexis Guichemerre , Luke McCaffrey , Mohammadhadi Shateri , Eric Granger

The integration of medical imaging and clinical text has enabled the emergence of generalist artificial intelligence (AI) systems for healthcare. However, pervasive biases, such as imbalanced disease prevalence, skewed anatomical region…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Cheng Li , Weijian Huang , Jiarun Liu , Hao Yang , Qi Yang , Song Wu , Ye Li , Hairong Zheng , Shanshan Wang

Publicly available biomedical videos, such as those on YouTube, serve as valuable educational resources for medical students. Unlike standard machine learning datasets, these videos are designed for human learners, often mixing medical…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Rahul Thapa , Andrew Li , Qingyang Wu , Bryan He , Yuki Sahashi , Christina Binder , Angela Zhang , Ben Athiwaratkun , Shuaiwen Leon Song , David Ouyang , James Zou

Large multimodal models (LMMs) have demonstrated significant potential in providing innovative solutions for various biomedical tasks, including pathology analysis, radiology report generation, and biomedical assistance. However, the…

Machine Learning · Computer Science 2025-12-30 Dong Xue , Ziyao Shao , Zhaoyang Duan , Fangzhou Liu , Bing Li , Zhongheng Zhang

Vision-and-language multi-modal pretraining and fine-tuning have shown great success in visual question answering (VQA). Compared to general domain VQA, the performance of biomedical VQA suffers from limited data. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Zheng Yuan , Qiao Jin , Chuanqi Tan , Zhengyun Zhao , Hongyi Yuan , Fei Huang , Songfang Huang

The clinical adoption of biomedical vision-language models is hindered by prompt optimization techniques that produce either uninterpretable latent vectors or single textual prompts. This lack of transparency and failure to capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Kaushitha Silva , Mansitha Eashwara , Sanduni Ubayasiri , Ruwan Tennakoon , Damayanthi Herath

Pretrained biomedical vision-language models (VLMs) such as BioMedCLIP perform well on average but often degrade on challenging modalities where inter-class margins are small and acquisition-specific variations are pronounced, especially…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Mainak Singha , Tanisha Gupta , Ankit Jha , Muhammad Haris Khan , Sayantani Ghosh , Biplab Banerjee

Instruction tuning large language models (LLMs) using machine-generated instruction-following data has improved zero-shot capabilities on new tasks, but the idea is less explored in the multimodal field. In this paper, we present the first…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Haotian Liu , Chunyuan Li , Qingyang Wu , Yong Jae Lee

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Recent advances in Multi-modal Large Language Models (MLLMs), such as LLaVA-series models, are driven by massive machine-generated instruction-following data tuning. Such automatic instruction collection pipelines, however, inadvertently…

Artificial Intelligence · Computer Science 2025-12-05 Hongzhe Huang , Jiang Liu , Zhewen Yu , Li Cai , Dian Jiao , Wenqiao Zhang , Siliang Tang , Juncheng Li , Hao Jiang , Haoyuan Li , Yueting Zhuang

Foundational models, pretrained on a large scale, have demonstrated substantial success across non-medical domains. However, training these models typically requires large, comprehensive datasets, which contrasts with the smaller and more…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Raphael Schäfer , Till Nicke , Henning Höfener , Annkristin Lange , Dorit Merhof , Friedrich Feuerhake , Volkmar Schulz , Johannes Lotz , Fabian Kiessling

Foundation models (FMs) have exhibited remarkable performance across a wide range of downstream tasks in many domains. Nevertheless, general-purpose FMs often face challenges when confronted with domain-specific problems, due to their…

Computational Engineering, Finance, and Science · Computer Science 2023-08-22 Yizhen Luo , Jiahuan Zhang , Siqi Fan , Kai Yang , Yushuai Wu , Mu Qiao , Zaiqing Nie