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Self-supervised learning (SSL) has become a powerful paradigm for learning from large, unlabeled datasets, particularly in computer vision (CV). However, applying SSL to multispectral remote sensing (RS) images presents unique challenges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Tom Burgert , Leonard Hackel , Paolo Rota , Begüm Demir

Convolutional Neural Networks (CNN) have been rigorously studied for Hyperspectral Image Classification (HSIC) and are known to be effective in exploiting joint spatial-spectral information with the expense of lower generalization…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Muhammad Ahmad , Manuel Mazzara , Salvatore Distefano

Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offers an unprecedented opportunity to study this, providing in…

Machine Learning · Computer Science 2026-02-16 Rui Yan , Xiaohan Xing , Xun Wang , Zixia Zhou , Md Tauhidul Islam , Lei Xing

Spatial transcriptomics (ST) profiles gene expression across a tissue section while preserving the spatial coordinates. Because current ST technologies typically profile two-dimensional tissue slices, integrating and aligning slices from…

Quantitative Methods · Quantitative Biology 2026-03-20 Yaqi Wu , Jingfeng Wang , Xin Maizie Zhou , Yanxiang Zhao , Zixuan Cang

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

Although efficient extraction of discriminative spatial-spectral features is critical for hyperspectral images classification (HSIC), it is difficult to achieve these features due to factors such as the spatial-spectral heterogeneity and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Yimin Zhu , Linlin Xu

Spatial Transcriptomics (ST) provides spatially-resolved gene expression, offering crucial insights into tissue architecture and complex diseases. However, its prohibitive cost limits widespread adoption, leading to significant attention on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Taejin Jeong , Joohyeok Kim , Jinyeong Kim , Chanyoung Kim , Seong Jae Hwang

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Symbolic regression (SR) aims to discover mathematical expressions from data, a task traditionally tackled using Genetic Programming (GP) through combinatorial search over symbolic structures. Latent Space Optimization (LSO) methods use…

Neural and Evolutionary Computing · Computer Science 2026-04-14 Benjamin Léger , Kazem Meidani , Christian Gagné

Spatio-Temporal Graph (STG) forecasting is a fundamental task in many real-world applications. Spatio-Temporal Graph Neural Networks have emerged as the most popular method for STG forecasting, but they often struggle with temporal…

Machine Learning · Computer Science 2023-09-26 Yutong Xia , Yuxuan Liang , Haomin Wen , Xu Liu , Kun Wang , Zhengyang Zhou , Roger Zimmermann

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

While recent studies on pedestrian attribute recognition have shown remarkable progress in leveraging complicated networks and attention mechanisms, most of them neglect the inter-image relations and an important prior: spatial consistency…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Jian Jia , Xiaotang Chen , Kaiqi Huang

Weather Forecasting is an attractive challengeable task due to its influence on human life and complexity in atmospheric motion. Supported by massive historical observed time series data, the task is suitable for data-driven approaches,…

Machine Learning · Computer Science 2022-09-20 Minbo Ma , Peng Xie , Fei Teng , Tianrui Li , Bin Wang , Shenggong Ji , Junbo Zhang

Computer Vision has proven to be a powerful tool for analyzing Spatial Transcriptomics (ST) data. However, current models that predict spatially resolved gene expression from histopathology images suffer from significant limitations due to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Paula Cárdenas , Leonardo Manrique , Daniela Vega , Daniela Ruiz , Pablo Arbeláez

Synthetic lethality (SL) prediction is used to identify if the co-mutation of two genes results in cell death. The prevalent strategy is to abstract SL prediction as an edge classification task on gene nodes within SL data and achieve it…

Machine Learning · Computer Science 2023-10-18 Xusheng Zhao , Hao Liu , Qiong Dai , Hao Peng , Xu Bai , Huailiang Peng

Spatial transcriptomics (ST) is a promising technique that characterizes the spatial gene profiling patterns within the tissue context. Comprehensive ST analysis depends on consecutive slices for 3D spatial insights, whereas the missing…

Image and Video Processing · Electrical Eng. & Systems 2025-05-19 NingFeng Que , Xiaofei Wang , Jingjing Chen , Yixuan Jiang , Chao Li

The spatio-spectral total variation (SSTV) model has been widely used as an effective regularization of hyperspectral images (HSI) for various applications such as mixed noise removal. However, since SSTV computes local spatial differences…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Shingo Takemoto , Kazuki Naganuma , Shunsuke Ono

This paper presents a new supervised classification algorithm for remotely sensed hyperspectral image (HSI) which integrates spectral and spatial information in a unified Bayesian framework. First, we formulate the HSI classification…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 Xiangyong Cao , Feng Zhou , Lin Xu , Deyu Meng , Zongben Xu , John Paisley

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson