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Convolutional neural networks have been widely applied to hyperspectral image classification. However, traditional convolutions can not effectively extract features for objects with irregular distributions. Recent methods attempt to address…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Di Wang , Bo Du , Liangpei Zhang

Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell…

Genomics · Quantitative Biology 2025-12-15 Hiren Madhu , João Felipe Rocha , Tinglin Huang , Siddharth Viswanath , Smita Krishnaswamy , Rex Ying

The rapid growth of digital pathology and advances in self-supervised deep learning have enabled the development of foundational models for various pathology tasks across diverse diseases. While multimodal approaches integrating diverse…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Kimberly Flores , Anthony Sisk , William Speier , Corey W. Arnold

Spatial transcriptomics (ST) technologies enable gene expression profiling with spatial resolution, offering unprecedented insights into tissue organization and disease heterogeneity. However, current analysis methods often struggle with…

Crime has become a major concern in many cities, which calls for the rising demand for timely predicting citywide crime occurrence. Accurate crime prediction results are vital for the beforehand decision-making of government to alleviate…

Machine Learning · Computer Science 2022-08-19 Zhonghang Li , Chao Huang , Lianghao Xia , Yong Xu , Jian Pei

Deep learning models are modern tools for spatio-temporal graph (STG) forecasting. Though successful, we argue that data scarcity is a key factor limiting their recent improvements. Meanwhile, contrastive learning has been an effective…

Machine Learning · Computer Science 2022-11-04 Xu Liu , Yuxuan Liang , Chao Huang , Yu Zheng , Bryan Hooi , Roger Zimmermann

Predicting spatial gene expression from H&E histology offers a scalable and clinically accessible alternative to sequencing, but realizing clinical impact requires models that generalize across cancer types and capture biologically coherent…

Machine Learning · Computer Science 2026-02-10 Susu Hu , Qinghe Zeng , Nithya Bhasker , Jakob Nikolas Kather , Stefanie Speidel

Hyperspectral image (HSI) clustering is a challenging task due to its high complexity. Despite subspace clustering shows impressive performance for HSI, traditional methods tend to ignore the global-local interaction in HSI data. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Jingxin Wang , Renxiang Guan , Kainan Gao , Zihao Li , Hao Li , Xianju Li , Chang Tang

When approaching the semantic segmentation of overhead imagery in the decimeter spatial resolution range, successful strategies usually combine powerful methods to learn the visual appearance of the semantic classes (e.g. convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Michele Volpi , Devis Tuia

Spatial-temporal graph learning has emerged as a promising solution for modeling structured spatial-temporal data and learning region representations for various urban sensing tasks such as crime forecasting and traffic flow prediction.…

Machine Learning · Computer Science 2023-06-21 Qianru Zhang , Chao Huang , Lianghao Xia , Zheng Wang , Siuming Yiu , Ruihua Han

In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Miguel Monteiro , Loïc Le Folgoc , Daniel Coelho de Castro , Nick Pawlowski , Bernardo Marques , Konstantinos Kamnitsas , Mark van der Wilk , Ben Glocker

Individual trajectories, rich in human-environment interaction information across space and time, serve as vital inputs for geospatial foundation models (GeoFMs). However, existing attempts at learning trajectory representations have…

Machine Learning · Computer Science 2025-05-13 Fei Huang , Jianrong Lv , Yang Yue

Graph-based semi-supervised learning methods, which deal well with the situation of limited labeled data, have shown dominant performance in practical applications. However, the high dimensionality of hyperspectral images (HSI) makes it…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Yanling Miao , Qi Wang , Mulin Chen , Xuelong Li

The integration of spatial multi-omics data from single tissues is crucial for advancing biological research. However, a significant data imbalance impedes progress: while spatial transcriptomics data is relatively abundant, spatial…

Artificial Intelligence · Computer Science 2026-02-06 Zhaorui Jiang , Yingfang Yuan , Lei Hu , Wei Pang

Spatial transcriptomics (ST) measures gene expression at a set of spatial locations in a tissue. Communities of nearby cells that express similar genes form \textit{spatial domains}. Specialized ST clustering algorithms have been developed…

Quantitative Methods · Quantitative Biology 2025-11-12 Perry Beamer , Zixuan Cang

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi

Spatial Transformer Networks (STNs) estimate image transformations that can improve downstream tasks by `zooming in' on relevant regions in an image. However, STNs are hard to train and sensitive to mis-predictions of transformations. To…

Machine Learning · Computer Science 2022-06-16 Pola Schwöbel , Frederik Warburg , Martin Jørgensen , Kristoffer H. Madsen , Søren Hauberg

The field of self-supervised 3D representation learning has emerged as a promising solution to alleviate the challenge presented by the scarcity of extensive, well-annotated datasets. However, it continues to be hindered by the lack of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Yunsong Wang , Na Zhao , Gim Hee Lee

Spatially resolved transcriptomics represents a significant advancement in single-cell analysis by offering both gene expression data and their corresponding physical locations. However, this high degree of spatial resolution entails a…

Genomics · Quantitative Biology 2024-03-19 Xiaoyu Li , Wenwen Min , Shunfang Wang , Changmiao Wang , Taosheng Xu

A scalable and robust 3D tissue transcriptomics profile can enable a holistic understanding of tissue organization and provide deeper insights into human biology and disease. Most predictive algorithms that infer ST directly from histology…

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