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This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Conversational Health Agents (CHAs) are interactive systems that provide healthcare services, such as assistance and diagnosis. Current CHAs, especially those utilizing Large Language Models (LLMs), primarily focus on conversation aspects.…

Computation and Language · Computer Science 2024-09-26 Mahyar Abbasian , Iman Azimi , Amir M. Rahmani , Ramesh Jain

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Multimodal Large Language Model (MLLM) has recently garnered attention as a prominent research focus. By harnessing powerful LLM, it facilitates a transition of conversational generative AI from unimodal text to performing multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Xuechen Guo , Wenhao Chai , Shi-Yan Li , Gaoang Wang

The quickly-expanding nature of published medical literature makes it challenging for clinicians and researchers to keep up with and summarize recent, relevant findings in a timely manner. While several closed-source summarization tools…

Information Retrieval · Computer Science 2023-10-26 Alejandro Lozano , Scott L Fleming , Chia-Chun Chiang , Nigam Shah

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks…

Computation and Language · Computer Science 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Zewen Qiang , Sendong Zhao , Bing Qin , Ting Liu

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

Computation and Language · Computer Science 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

Objective: To enhance health literacy and accessibility of health information for a diverse patient population by developing a patient-centered artificial intelligence (AI) solution using large language models (LLMs) and Fast Healthcare…

Computers and Society · Computer Science 2024-02-06 Paul Schmiedmayer , Adrit Rao , Philipp Zagar , Vishnu Ravi , Aydin Zahedivash , Arash Fereydooni , Oliver Aalami

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Despite the vast repository of global medical knowledge predominantly being in English, local languages are crucial for delivering tailored healthcare services, particularly in areas with limited medical resources. To extend the reach of…

Computation and Language · Computer Science 2024-10-15 Xidong Wang , Nuo Chen , Junyin Chen , Yidong Wang , Guorui Zhen , Chunxian Zhang , Xiangbo Wu , Yan Hu , Anningzhe Gao , Xiang Wan , Haizhou Li , Benyou Wang

Aligning large language models (LLMs) with human preferences has proven to drastically improve usability and has driven rapid adoption as demonstrated by ChatGPT. Alignment techniques such as supervised fine-tuning (SFT) and reinforcement…

Large language models (LLMs) have exhibited remarkable capabilities across various domains and tasks, pushing the boundaries of our knowledge in learning and cognition. The latest model, OpenAI's o1, stands out as the first LLM with an…

Computation and Language · Computer Science 2024-09-24 Yunfei Xie , Juncheng Wu , Haoqin Tu , Siwei Yang , Bingchen Zhao , Yongshuo Zong , Qiao Jin , Cihang Xie , Yuyin Zhou

We introduce BiMediX2, a bilingual (Arabic-English) Bio-Medical EXpert Large Multimodal Model that supports text-based and image-based medical interactions. It enables multi-turn conversation in Arabic and English and supports diverse…

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to…

Med42-v2 introduces a suite of clinical large language models (LLMs) designed to address the limitations of generic models in healthcare settings. These models are built on Llama3 architecture and fine-tuned using specialized clinical data.…

Computation and Language · Computer Science 2024-08-13 Clément Christophe , Praveen K Kanithi , Tathagata Raha , Shadab Khan , Marco AF Pimentel

Nowadays, open-source large language models like LLaMA have emerged. Recent developments have incorporated supervised fine-tuning (SFT) and reinforcement learning fine-tuning (RLFT) to align these models with human goals. However, SFT…

Computation and Language · Computer Science 2024-03-19 Guan Wang , Sijie Cheng , Xianyuan Zhan , Xiangang Li , Sen Song , Yang Liu

This paper presents a comprehensive evaluation of cost-efficient Large Language Models (LLMs) for diverse biomedical tasks spanning both text and image modalities. We evaluated a range of closed-source and open-source LLMs on tasks such as…

Computation and Language · Computer Science 2025-07-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Large Language Models (LLMs) fine-tuned via Reinforcement Learning from Human Feedback (RLHF) and Reinforcement Learning with Verifiable Rewards (RLVR) significantly improve the alignment of human-AI values, further raising the upper bound…

Artificial Intelligence · Computer Science 2025-10-10 Jian Hu , Xibin Wu , Wei Shen , Jason Klein Liu , Zilin Zhu , Weixun Wang , Songlin Jiang , Haoran Wang , Hao Chen , Bin Chen , Weikai Fang , Xianyu , Yu Cao , Haotian Xu , Yiming Liu