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Deep learning models for medical image segmentation can fail unexpectedly and spectacularly for pathological cases and images acquired at different centers than training images, with labeling errors that violate expert knowledge. Such…

Automatic segmentation of fine-grained brain structures remains a challenging task. Current segmentation methods mainly utilize 2D and 3D deep neural networks. The 2D networks take image slices as input to produce coarse segmentation in…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Yuemeng Li , Hangfan Liu , Hongming Li , Yong Fan

Segmentation of brain structures on MRI is the primary step for further quantitative analysis of brain diseases. Manual segmentation is still considered the gold standard in terms of accuracy; however, such data is extremely time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Mengyu Li , Magnus Magnusson , Thilo van Eimeren , Lotta M. Ellingsen

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

Accurate and automatic segmentation of brain tumors in multi-parametric magnetic resonance imaging (mpMRI) is essential for quantitative measurements, which play an increasingly important role in clinical diagnosis and prognosis. The…

Deep learning models trained with large amounts of data have become a recent and effective approach to predictive problem solving -- these have become known as "foundation models" as they can be used as fundamental tools for other…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 José Guilherme de Almeida , Nuno M. Rodrigues , Sara Silva , Nickolas Papanikolaou

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Medical image segmentation being a substantial component of image processing plays a significant role to analyze gross anatomy, to locate an infirmity and to plan the surgical procedures. Segmentation of brain Magnetic Resonance Imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Mustansar Fiaz , Kamran Ali , Abdul Rehman , M. Junaid Gul , Soon Ki Jung

Purpose: AI in radiology is hindered chiefly by: 1) Requiring large annotated data sets. 2) Non-generalizability that limits deployment to new scanners / institutions. And 3) Inadequate explainability and interpretability. We believe that…

Artificial Intelligence · Computer Science 2020-08-07 Joseph Stember , Hrithwik Shalu

The successful adaptation of foundation models to multi-modal medical imaging is a critical yet unresolved challenge. Existing models often struggle to effectively fuse information from multiple sources and adapt to the heterogeneous nature…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shadi Alijani , Fereshteh Aghaee Meibodi , Homayoun Najjaran

In modern medical diagnostics, magnetic resonance imaging (MRI) is an important technique that provides detailed insights into anatomical structures. In this paper, we present a comprehensive methodology focusing on streamlining the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Siddharth Jha , Zichen Gui , Benjamin Delbos , Richard Moreau , Arnaud Leleve , Irene Cheng

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Magnetic resonance imaging (MRI) is a crucial medical imaging modality. However, long acquisition times remain a significant challenge, leading to increased costs, and reduced patient comfort. Recent studies have shown the potential of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Amirmohammad Shamaei , Alexander Stebner , Salome , Bosshart , Johanna Ospel , Gouri Ginde , Mariana Bento , Roberto Souza

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Multimodal 3D MRI brain tumor segmentation is a pivotal step in radiotherapy target delineation, surgical planning and post-treatment assessment. Existing methods often assume artifact-free MRI images. However, inevitable patient motion…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 Yuchun Wang , Xiaosong Li , Gefei Liang , Yang Liu

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

In the past five years, the use of generative and foundational AI systems has greatly improved the decoding of brain activity. Visual perception, in particular, can now be decoded from functional Magnetic Resonance Imaging (fMRI) with…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Yohann Benchetrit , Hubert Banville , Jean-Rémi King