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Interpretable machine learning has exploded as an area of interest over the last decade, sparked by the rise of increasingly large datasets and deep neural networks. Simultaneously, large language models (LLMs) have demonstrated remarkable…

Computation and Language · Computer Science 2024-02-06 Chandan Singh , Jeevana Priya Inala , Michel Galley , Rich Caruana , Jianfeng Gao

Machine learning enables extracting clinical insights from large temporal datasets. The applications of such machine learning models include identifying disease patterns and predicting patient outcomes. However, limited interpretability…

Machine Learning · Computer Science 2023-11-30 Yu Chen , Nivedita Bijlani , Samaneh Kouchaki , Payam Barnaghi

There exist applications of reinforcement learning like medicine where policies need to be ''interpretable'' by humans. User studies have shown that some policy classes might be more interpretable than others. However, it is costly to…

Machine Learning · Computer Science 2025-03-12 Hector Kohler , Quentin Delfosse , Waris Radji , Riad Akrour , Philippe Preux

Machine learning has recently been widely adopted to address the managerial decision making problems, in which the decision maker needs to be able to interpret the contributions of individual attributes in an explicit form. However, there…

Machine Learning · Computer Science 2019-10-28 Mengzhuo Guo , Qingpeng Zhang , Xiuwu Liao , Frank Youhua Chen , Daniel Dajun Zeng

Interpretability is essential for machine learning algorithms in high-stakes application fields such as medical image analysis. However, high-performing black-box neural networks do not provide explanations for their predictions, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Susu Sun , Stefano Woerner , Andreas Maier , Lisa M. Koch , Christian F. Baumgartner

Interpretable machine learning (IML) becomes increasingly important in highly regulated industry sectors related to the health and safety or fundamental rights of human beings. In general, the inherently IML models should be adopted because…

Machine Learning · Computer Science 2021-11-03 Agus Sudjianto , Aijun Zhang

The thesis explores the role machine learning methods play in creating intuitive computational models of neural processing. Combined with interpretability techniques, machine learning could replace human modeler and shift the focus of human…

Neurons and Cognition · Quantitative Biology 2020-10-20 Ilya Kuzovkin

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Most of the work on interpretable machine learning has focused on designing either inherently interpretable models, which typically trade-off accuracy for interpretability, or post-hoc explanation systems, which lack guarantees about their…

Machine Learning · Computer Science 2019-06-05 Gregory Plumb , Maruan Al-Shedivat , Eric Xing , Ameet Talwalkar

In many scenarios, the interpretability of machine learning models is a highly required but difficult task. To explain the individual predictions of such models, local model-agnostic approaches have been proposed. However, the process…

Machine Learning · Statistics 2025-10-22 Gianluigi Lopardo , Frederic Precioso , Damien Garreau

Precision medicine is currently a topic of great interest in clinical and intervention science. One way to formalize precision medicine is through a treatment regime, which is a sequence of decision rules, one per stage of clinical…

Methodology · Statistics 2016-06-07 Yichi Zhang , Eric B. Laber , Anastasios Tsiatis , Marie Davidian

Many risk-sensitive applications require Machine Learning (ML) models to be interpretable. Attempts to obtain interpretable models typically rely on tuning, by trial-and-error, hyper-parameters of model complexity that are only loosely…

Machine Learning · Computer Science 2020-05-29 Marco Virgolin , Andrea De Lorenzo , Eric Medvet , Francesca Randone

Deep learning models developed for time-series associated tasks have become more widely researched nowadays. However, due to the unintuitive nature of time-series data, the interpretability problem -- where we understand what is under the…

Machine Learning · Computer Science 2023-05-25 Ziqi Zhao , Yucheng Shi , Shushan Wu , Fan Yang , Wenzhan Song , Ninghao Liu

Machine learning can be used to make sense of healthcare data. Probabilistic machine learning models help provide a complete picture of observed data in healthcare. In this review, we examine how probabilistic machine learning can advance…

Machine Learning · Statistics 2020-09-24 Irene Y. Chen , Shalmali Joshi , Marzyeh Ghassemi , Rajesh Ranganath

Embracing the pursuit of intrinsically explainable reinforcement learning raises crucial questions: what distinguishes explainability from interpretability? Should explainable and interpretable agents be developed outside of domains where…

Artificial Intelligence · Computer Science 2024-04-18 Hector Kohler , Quentin Delfosse , Paul Festor , Philippe Preux

What is it to interpret the outputs of an opaque machine learning model. One approach is to develop interpretable machine learning techniques. These techniques aim to show how machine learning models function by providing either model…

Machine Learning · Computer Science 2024-09-06 Andrew Smart , Atoosa Kasirzadeh

As the use of machine learning (ML) models in product development and data-driven decision-making processes became pervasive in many domains, people's focus on building a well-performing model has increasingly shifted to understanding how…

Human-Computer Interaction · Computer Science 2020-06-02 Sungsoo Ray Hong , Jessica Hullman , Enrico Bertini

Fairness of machine learning models in healthcare has drawn increasing attention from clinicians, researchers, and even at the highest level of government. On the other hand, the importance of developing and deploying interpretable or…

Machine Learning · Computer Science 2024-09-04 Mary M. Lucas , Xiaoyang Wang , Chia-Hsuan Chang , Christopher C. Yang , Jacqueline E. Braughton , Quyen M. Ngo

Machine Learning algorithms are increasingly being used in recent years due to their flexibility in model fitting and increased predictive performance. However, the complexity of the models makes them hard for the data analyst to interpret…

Machine Learning · Statistics 2018-06-07 Joel Vaughan , Agus Sudjianto , Erind Brahimi , Jie Chen , Vijayan N. Nair

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…