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Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Despite the growing body of work in interpretable machine learning, it remains unclear how to evaluate different explainability methods without resorting to qualitative assessment and user-studies. While interpretability is an inherently…

Machine Learning · Computer Science 2020-07-16 An-phi Nguyen , María Rodríguez Martínez

Machine learning (ML) techniques play a pivotal role in high-stakes domains such as healthcare, where accurate predictions can greatly enhance decision-making. However, most high-performing methods such as neural networks and ensemble…

Artificial Intelligence · Computer Science 2026-01-08 Sanne Wielinga , Jesse Heyninck

We present a brief history of the field of interpretable machine learning (IML), give an overview of state-of-the-art interpretation methods, and discuss challenges. Research in IML has boomed in recent years. As young as the field is, it…

Machine Learning · Statistics 2022-01-24 Christoph Molnar , Giuseppe Casalicchio , Bernd Bischl

Deep learning methods have become very popular for the processing of natural images, and were then successfully adapted to the neuroimaging field. As these methods are non-transparent, interpretability methods are needed to validate them…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Elina Thibeau-Sutre , Sasha Collin , Ninon Burgos , Olivier Colliot

Multi-agent robotic systems are increasingly operating in real-world environments in close proximity to humans, yet are largely controlled by policy models with inscrutable deep neural network representations. We introduce a method for…

Machine Learning · Computer Science 2023-02-24 Renos Zabounidis , Joseph Campbell , Simon Stepputtis , Dana Hughes , Katia Sycara

Neural networks have achieved remarkable success across various fields. However, the lack of interpretability limits their practical use, particularly in critical decision-making scenarios. Post-hoc interpretability, which provides…

Machine Learning · Computer Science 2025-11-21 Yang Ji , Ying Sun , Yuting Zhang , Zhigaoyuan Wang , Yuanxin Zhuang , Zheng Gong , Dazhong Shen , Chuan Qin , Hengshu Zhu , Hui Xiong

Focus in Explainable AI is shifting from explanations defined in terms of low-level elements, such as input features, to explanations encoded in terms of interpretable concepts learned from data. How to reliably acquire such concepts is,…

Machine Learning · Computer Science 2023-09-15 Emanuele Marconato , Andrea Passerini , Stefano Teso

While deep neural network models offer unmatched classification performance, they are prone to learning spurious correlations in the data. Such dependencies on confounding information can be difficult to detect using performance metrics if…

Machine Learning · Computer Science 2023-08-09 Susu Sun , Lisa M. Koch , Christian F. Baumgartner

Interpretability of epidemiological models is a key consideration, especially when these models are used in a public health setting. Interpretability is strongly linked to the identifiability of the underlying model parameters, i.e., the…

Interpretation of deep learning models is a very challenging problem because of their large number of parameters, complex connections between nodes, and unintelligible feature representations. Despite this, many view interpretability as a…

Machine Learning · Computer Science 2021-03-05 Michael Tsang , James Enouen , Yan Liu

Machine learning models that first learn a representation of a domain in terms of human-understandable concepts, then use it to make predictions, have been proposed to facilitate interpretation and interaction with models trained on…

Machine Learning · Computer Science 2020-12-08 Isaac Lage , Finale Doshi-Velez

The increasing use of complex machine learning models in education has led to concerns about their interpretability, which in turn has spurred interest in developing explainability techniques that are both faithful to the model's inner…

Machine Learning · Computer Science 2025-05-13 Juan D. Pinto , Luc Paquette

Artificial intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Machine Learning · Computer Science 2020-09-25 Vaishak Belle , Ioannis Papantonis

Interpretability allows the domain-expert to directly evaluate the model's relevance and reliability, a practice that offers assurance and builds trust. In the healthcare setting, interpretable models should implicate relevant biological…

Machine Learning · Computer Science 2020-06-18 Thomas P. Quinn , Dang Nguyen , Santu Rana , Sunil Gupta , Svetha Venkatesh

Supervised machine learning models boast remarkable predictive capabilities. But can you trust your model? Will it work in deployment? What else can it tell you about the world? We want models to be not only good, but interpretable. And yet…

Machine Learning · Computer Science 2017-03-07 Zachary C. Lipton

Most existing interpretable methods explain a black-box model in a post-hoc manner, which uses simpler models or data analysis techniques to interpret the predictions after the model is learned. However, they (a) may derive contradictory…

Machine Learning · Computer Science 2020-01-22 Mengzhuo Guo , Qingpeng Zhang , Xiuwu Liao , Daniel Dajun Zeng

In machine learning (ML), it is in general challenging to provide a detailed explanation on how a trained model arrives at its prediction. Thus, usually we are left with a black-box, which from a scientific standpoint is not satisfactory.…

Materials Science · Physics 2021-04-22 Luca M. Ghiringhelli

Machine learning is increasingly transforming various scientific fields, enabled by advancements in computational power and access to large data sets from experiments and simulations. As artificial intelligence (AI) continues to grow in…

Computational Physics · Physics 2025-04-01 Sebastian Johann Wetzel , Seungwoong Ha , Raban Iten , Miriam Klopotek , Ziming Liu

Although a recent shift has been made in the field of predictive process monitoring to use models from the explainable artificial intelligence field, the evaluation still occurs mainly through performance-based metrics, thus not accounting…

Machine Learning · Computer Science 2023-08-01 Alexander Stevens , Johannes De Smedt
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