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Knee osteoarthritis is a degenerative joint disease that induces chronic pain and disability. Bone morphological analysis is a promising tool to understand the mechanical aspect of this disorder. This study proposes a 2D bone morphological…

Classical radiomic features are designed to quantify image appearance and intensity patterns. Compared with end-to-end deep learning (DL) models trained for disease classification, radiomics pipelines with low-dimensional parametric…

We provide additional statistical background for the methodology developed in the clinical analysis of knee osteoarthritis in "A Precision Medicine Approach to Develop and Internally Validate Optimal Exercise and Weight Loss Treatments for…

The purposes of this study were to investigate: 1) the effect of placement of region-of-interest (ROI) for texture analysis of subchondral bone in knee radiographs, and 2) the ability of several texture descriptors to distinguish between…

Osteoarthritis (OA) is one of the major health issues among the elderly population. MRI is the most popular technology to observe and evaluate the progress of OA course. However, the extreme labor cost of MRI analysis makes the process…

Automated Kellgren--Lawrence (KL) grading from knee radiographs is challenging due to subtle structural changes, long-range anatomical dependencies, and ambiguity near grade boundaries. We propose AGE-Net, a ConvNeXt-based framework that…

Reliability theory is used to assess the sensitivity of a passive flexion and active flexion of the human lower leg Finite Element (FE) models with Total Knee Replacement (TKR) to the variability in the input parameters of the respective FE…

Electromyography (EMG) signals are widely used for predicting body joint angles through machine learning (ML) and deep learning (DL) methods. However, these approaches often face challenges such as limited real-time applicability,…

Chronic Kidney Disease (CKD) affects nearly 10\% of the global population and often progresses to end-stage renal failure. Accurate prognosis prediction is vital for timely interventions and resource optimization. We present a…

Acute Kidney Injury (AKI), the abrupt decline in kidney function due to temporary or permanent injury, is associated with increased mortality, morbidity, length of stay, and hospital cost. Sometimes, simple interventions such as medication…

Background-Prognostic predictive models are used in the delivery of primary care to estimate a patients risk of future disease development. Electronic medical record, EMR, data can be used for the construction of these models. Objectives-…

Purpose: To advance research in the field of machine learning for MR image reconstruction with an open challenge. Methods: We provided participants with a dataset of raw k-space data from 1,594 consecutive clinical exams of the knee. The…

Kidney stones are a common and debilitating health issue, and genetic factors play a crucial role in determining susceptibility. While Genome-Wide Association Studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs)…

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

Osteoporosis, characterized by reduced bone mineral density (BMD) and compromised bone microstructure, increases fracture risk in aging populations. While dual-energy X-ray absorptiometry (DXA) is the clinical standard for BMD assessment,…

Magnetic Resonance Imaging (MRI) is a widely-accepted imaging technique for knee injury analysis. Its advantage of capturing knee structure in three dimensions makes it the ideal tool for radiologists to locate potential tears in the knee.…

Adaptive intelligence aims at empowering machine learning techniques with the additional use of domain knowledge. In this work, we present the application of adaptive intelligence to accelerate MR acquisition. Starting from undersampled…

Accurate reconstruction of implanted knee models is crucial in orthopedic surgery and biomedical engineering, enhancing preoperative planning, optimizing implant design, and improving surgical outcomes. Traditional methods rely on…

Background: Clear cell renal cell carcinoma (ccRCC) is the most common renal-related tumor with high heterogeneity. There is still an urgent need for novel diagnostic and prognostic biomarkers for ccRCC. Methods: We proposed a…

Deep learning approaches have recently shown great promise in accelerating magnetic resonance image (MRI) acquisition. The majority of existing work have focused on designing better reconstruction models given a pre-determined acquisition…