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Introduction: We describe the foundation of PETRIC, an image reconstruction challenge to minimise the computational runtime of related algorithms for Positron Emission Tomography (PET). Purpose: Although several similar challenges are…

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

In nuclear imaging, limited resolution causes partial volume effects (PVEs) that affect image sharpness and quantitative accuracy. Partial volume correction (PVC) methods incorporating high-resolution anatomical information from CT or MRI…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Huidong Xie , Zhao Liu , Luyao Shi , Kathleen Greco , Xiongchao Chen , Bo Zhou , Attila Feher , John C. Stendahl , Nabil Boutagy , Tassos C. Kyriakides , Ge Wang , Albert J. Sinusas , Chi Liu

Remote photoplethysmography (rPPG) allows for noncontact monitoring of blood volume changes from a camera by detecting minor fluctuations in reflected light. Prior applications of rPPG focused on face videos. In this paper we explored the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Lu Niu , Jeremy Speth , Nathan Vance , Benjamin Sporrer , Adam Czajka , Patrick Flynn

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Background. Clinical parameters measured from gated single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) have value in predicting cardiac resynchronization therapy (CRT) patient outcomes, but still show…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Kristoffer Larsena , Zhuo He , Chen Zhao , Xinwei Zhang , Quiying Sha , Claudio T Mesquitad , Diana Paeze , Ernest V. Garciaf , Jiangang Zou , Amalia Peix , Weihua Zhou

The growing integration of smart environments and low-power computing devices, coupled with mass-market sensor technologies, is driving advancements in remote and non-contact physiological monitoring. However, deploying these systems in…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Constantino Álvarez Casado , Sasan Sharifipour , Manuel Lage Cañellas , Nhi Nguyen , Le Nguyen , Miguel Bordallo López

Purpose. Photoplethysmography (PPG) is a non-invasive technique that measures changes in blood flow volume through optical means. Previous research has established the feasibility of PPG peak detection based on the crossover of moving…

Signal Processing · Electrical Eng. & Systems 2023-12-18 Cesar Abascal Machado , Victor O. Costa , Cesar Augusto Prior , Cesar Ramos Rodrigues

Whole-body PET imaging is often hindered by respiratory motion during acquisition, causing significant degradation in the quality of reconstructed activity images. An additional challenge in PET/CT imaging arises from the respiratory phase…

Cardiac 18F-FDG PET has been used in clinics to assess myocardial glucose metabolism. Its ability for imaging myocardial glucose transport, however, has rarely been exploited in clinics. Using the dynamic FDG-PET scans of ten patients with…

Medical Physics · Physics 2020-10-27 Yang Zuo , Ramsey D. Badawi , Cameron C. Foster , Thomas Smith , Javier E. Lopez , Guobao Wang

High-resolution magnetic resonance imaging (MRI) is essential in clinical diagnosis. However, its long acquisition time remains a critical issue. Parallel imaging (PI) is a common approach to reduce acquisition time by periodically skipping…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Hao Li , Yusheng Zhou , Jianan Liu , Xiling Liu , Tao Huang , Zhihan Lyu , Weidong Cai , Wei Chen

Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines…

Quantitative Methods · Quantitative Biology 2014-05-28 Kevin J. Black , Jonathan M. Koller , Brad D. Miller

Precise quantitative delineation of tumor hypoxia is essential in radiation therapy treatment planning to improve the treatment efficacy by targeting hypoxic sub-volumes. We developed a combined imaging system of positron emission…

Volumetric, multimodal imaging with precise spatial and temporal co-registration can provide valuable and complementary information for diagnosis and monitoring. Considerable research has sought to combine 3D photoacoustic (PA) and…

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Photoacoustic computed tomography (PACT) is emerging as a new technique for functional brain imaging, primarily due to its capabilities in label-free hemodynamic imaging. Despite its potential, the transcranial application of PACT has…

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

Dynamic PET kinetic modeling increasingly demands voxelwise uncertainty quantification and robust model selection. Yet total-body PET (TB-PET) data volumes make conventional Bayesian approaches, such as per-voxel MCMC, computationally…

Applications · Statistics 2026-03-17 Qinlin Gu , Gaelle M. Emvalomenos , Evan D. Morris , Clara Grazian , Steven R. Meikle

We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is…

Clinical SPECT-MPI images of 345 patients acquired from a dedicated cardiac SPECT in list-mode format were retrospectively employed to predict normal-dose images from low-dose data at the half, quarter, and one-eighth-dose levels. A…