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Counterfactual prediction is about predicting outcome of the unobserved situation from the data. For example, given patient is on drug A, what would be the outcome if she switch to drug B. Most of existing works focus on modeling…

Machine Learning · Computer Science 2020-10-29 Yanbo Xu , Cao Xiao , Jimeng Sun

We highlight a failure mode of large reasoning models on questions with insufficient information: models may recognize that a problem is under-specified, yet still continue reasoning and produce unsupported final answers instead of…

Artificial Intelligence · Computer Science 2026-05-28 Renjie Gu , Jiaxu Li , Yihao Wang , Yun Yue , Hansong Xiao , Yefei Chen , Yuan Wang , Chunxiao Guo , Pei Wei , Jinjie Gu , Yixin Cao

We consider the task of evaluating policies of algorithmic resource allocation through randomized controlled trials (RCTs). Such policies are tasked with optimizing the utilization of limited intervention resources, with the goal of…

Artificial Intelligence · Computer Science 2023-02-07 Aditya Mate , Bryan Wilder , Aparna Taneja , Milind Tambe

Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , David Cornell , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Missing outcome data is one of the principal threats to the validity of treatment effect estimates from randomized trials. The outcome distributions of participants with missing and observed data are often different, which increases the…

Methodology · Statistics 2017-04-06 Iván Díaz , Mark J. van der Laan

Finetuning foundation models for specific tasks is an emerging paradigm in modern machine learning. The efficacy of task-specific finetuning largely depends on the selection of appropriate training data. We present TSDS (Task-Specific Data…

Machine Learning · Computer Science 2024-12-30 Zifan Liu , Amin Karbasi , Theodoros Rekatsinas

Tinnitus is a prevalent hearing disorder that can be caused by various factors such as age, hearing loss, exposure to loud noises, ear infections or tumors, certain medications, head or neck injuries, and psychological conditions like…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Farzaneh Ramezani , Hamidreza Bolhasani

Reinforcement learning based recommender systems (RL-based RS) aim at learning a good policy from a batch of collected data, by casting recommendations to multi-step decision-making tasks. However, current RL-based RS research commonly has…

Information Retrieval · Computer Science 2023-04-18 Kai Wang , Zhene Zou , Minghao Zhao , Qilin Deng , Yue Shang , Yile Liang , Runze Wu , Xudong Shen , Tangjie Lyu , Changjie Fan

In epidemiological studies, participants' disease status is often collected through self-reported outcomes in place of formal medical tests due to budget constraints. However, self-reported outcomes are often subject to measurement errors,…

Methodology · Statistics 2023-06-21 Yujie Wu , Molin Wang

Hallucinations in medical large language models (LLMs) remain a safety-critical issue, particularly when available evidence is insufficient or conflicting. We study this problem in diabetic retinopathy (DR) decision settings and introduce…

Artificial Intelligence · Computer Science 2026-04-08 Zhe Yu , Wenpeng Xing , Meng Han

Reinforcement learning (RL) has the potential to significantly improve clinical decision making. However, treatment policies learned via RL from observational data are sensitive to subtle choices in study design. We highlight a simple…

Machine Learning · Computer Science 2020-12-23 Christina X. Ji , Michael Oberst , Sanjat Kanjilal , David Sontag

Extracting patient information from unstructured text is a critical task in health decision-support and clinical research. Large language models (LLMs) have shown the potential to accelerate clinical curation via few-shot in-context…

Computation and Language · Computer Science 2023-06-21 Zelalem Gero , Chandan Singh , Hao Cheng , Tristan Naumann , Michel Galley , Jianfeng Gao , Hoifung Poon

This work presents a swift method to assess the efficacy of particular types of instruction-tuning data, utilizing just a handful of probe examples and eliminating the need for model retraining. This method employs the idea of…

Computation and Language · Computer Science 2025-02-20 Minlong Peng , Jingyi Yang , Zhongjun He , Hua Wu

There is an emerging trend in the reinforcement learning for healthcare literature. In order to prepare longitudinal, irregularly sampled, clinical datasets for reinforcement learning algorithms, many researchers will resample the time…

Machine Learning · Computer Science 2019-11-19 Scott L. Fleming , Kuhan Jeyapragasan , Tony Duan , Daisy Ding , Saurabh Gombar , Nigam Shah , Emma Brunskill

Deep Neural Networks (DNNs) have become key components of many safety-critical applications such as autonomous driving and medical diagnosis. However, DNNs have been shown suffering from poor robustness because of their susceptibility to…

Machine Learning · Computer Science 2020-07-28 Wenjie Wan , Zhaodi Zhang , Yiwei Zhu , Min Zhang , Fu Song

With recent achievements in tasks requiring context awareness, foundation models have been adopted to treat large-scale data from electronic health record (EHR) systems. However, previous clinical recommender systems based on foundation…

Artificial Intelligence · Computer Science 2023-02-02 Seunghyun Lee , Da Young Lee , Sujeong Im , Nan Hee Kim , Sung-Min Park

Randomized controlled trials (RCTs) are the gold standard for evaluating the causal effect of a treatment; however, they often have limited sample sizes and sometimes poor generalizability. On the other hand, non-randomized, observational…

Methodology · Statistics 2021-09-23 Shuxiao Chen , Bo Zhang , Ting Ye

Reinforcement learning (RL) has achieved remarkable success in real-world decision-making across diverse domains, including gaming, robotics, online advertising, public health, and natural language processing. Despite these advances, a…

Applications · Statistics 2026-01-23 Asim H. Gazi , Yongyi Guo , Daiqi Gao , Ziping Xu , Kelly W. Zhang , Susan A. Murphy

Developing 3D vision-language models with robust clinical reasoning remains a challenge due to the inherent complexity of volumetric medical imaging, the tendency of models to overfit superficial report patterns, and the lack of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Haoran Lai , Zihang Jiang , Kun Zhang , Qingsong Yao , Rongsheng Wang , Zhiyang He , Xiaodong Tao , Wei Wei , Shaohua Kevin Zhou

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn