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Artificial Intelligence (AI) advancement is heavily dependent on access to large-scale, high-quality training data. However, in specialized domains such as healthcare, data acquisition faces significant constraints due to privacy…

Human-Computer Interaction · Computer Science 2025-02-11 Nina Freise , Marius Heitlinger , Ruben Nuredini , Gerrit Meixner

Medical imaging is an essential tool for diagnosing and treating diseases. However, lacking medical images can lead to inaccurate diagnoses and ineffective treatments. Generative models offer a promising solution for addressing medical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-02 M. AbdulRazek , G. Khoriba , M. Belal

Synthetic clinical data are increasingly important for advancing AI in healthcare, given strict privacy constraints on real-world EHRs, limited availability of annotated rare-condition data, and systemic biases in observational datasets.…

Machine Learning · Computer Science 2025-09-16 Rumeng Li , Xun Wang , Hong Yu

Recent breakthroughs in synthetic data generation approaches made it possible to produce highly photorealistic images which are hardly distinguishable from real ones. Furthermore, synthetic generation pipelines have the potential to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Alon Shoshan , Nadav Bhonker , Igor Kviatkovsky , Matan Fintz , Gerard Medioni

Accurately evaluating model performance is crucial for deploying machine learning systems in real-world applications. Traditional methods often require a sufficiently large labeled test set to ensure a reliable evaluation. However, in many…

Machine Learning · Computer Science 2025-11-04 Hai Hoang Thanh , Duy-Tung Nguyen , Hung The Tran , Khoat Than

While synthetic tabular data generation using Deep Generative Models (DGMs) offers a compelling solution to data scarcity and privacy concerns, their effectiveness relies on the availability of substantial training data, often lacking in…

Machine Learning · Computer Science 2025-08-01 Patricia A. Apellániz , Ana Jiménez , Borja Arroyo Galende , Juan Parras , Santiago Zazo

Analyzing data from past clinical trials is part of the ongoing effort to optimize the design, implementation, and execution of new clinical trials and more efficiently bring life-saving interventions to market. While there have been recent…

Machine Learning · Computer Science 2024-12-16 Chufan Gao , Mandis Beigi , Afrah Shafquat , Jacob Aptekar , Jimeng Sun

Access to large-scale high-quality healthcare databases is key to accelerate medical research and make insightful discoveries about diseases. However, access to such data is often limited by patient privacy concerns, data sharing…

This paper addresses the challenge of overfitting in the learning of dynamical systems by introducing a novel approach for the generation of synthetic data, aimed at enhancing model generalization and robustness in scenarios characterized…

Machine Learning · Computer Science 2024-03-11 Dario Piga , Matteo Rufolo , Gabriele Maroni , Manas Mejari , Marco Forgione

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

The widespread use of big data across sectors has raised major privacy concerns, especially when sensitive information is shared or analyzed. Regulations such as GDPR and HIPAA impose strict controls on data handling, making it difficult to…

Machine Learning · Computer Science 2025-12-10 Anantaa Kotal , Anupam Joshi

Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating…

Machine Learning · Computer Science 2019-11-28 Saloni Dash , Ritik Dutta , Isabelle Guyon , Adrien Pavao , Andrew Yale , Kristin P. Bennett

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Machine learning heavily relies on data, but real-world applications often encounter various data-related issues. These include data of poor quality, insufficient data points leading to under-fitting of machine learning models, and…

Machine Learning · Computer Science 2025-04-07 Yingzhou Lu , Lulu Chen , Yuanyuan Zhang , Minjie Shen , Huazheng Wang , Xiao Wang , Capucine van Rechem , Tianfan Fu , Wenqi Wei

Each year, hundreds of clinical trials are conducted to evaluate new medical interventions, but sharing patient records from these trials with other institutions can be challenging due to privacy concerns and federal regulations. To help…

Machine Learning · Computer Science 2025-02-19 Trisha Das , Zifeng Wang , Afrah Shafquat , Mandis Beigi , Jason Mezey , Jacob Aptekar , Jimeng Sun

Synthetic healthcare data generation presents a viable approach to enhance data accessibility and support research by overcoming limitations associated with real-world medical datasets. However, ensuring fairness across protected attributes…

Machine Learning · Computer Science 2025-11-04 Sama Salarian , Yue Zhang , Swati Padhee , Srinivasan Parthasarathy

Synthetic data generation is widely known to boost the accuracy of neural grammatical error correction (GEC) systems, but existing methods often lack diversity or are too simplistic to generate the broad range of grammatical errors made by…

Computation and Language · Computer Science 2021-05-28 Felix Stahlberg , Shankar Kumar

The widespread adoption of electronic health records (EHRs) and subsequent increased availability of longitudinal healthcare data has led to significant advances in our understanding of health and disease with direct and immediate impact on…

Machine Learning · Computer Science 2022-01-21 Simon Bing , Andrea Dittadi , Stefan Bauer , Patrick Schwab

In the medical field, the limited availability of large-scale datasets and labor-intensive annotation processes hinder the performance of deep models. Diffusion-based generative augmentation approaches present a promising solution to this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Xinrui Zhou , Yuhao Huang , Haoran Dou , Shijing Chen , Ao Chang , Jia Liu , Weiran Long , Jian Zheng , Erjiao Xu , Jie Ren , Alejandro F. Frangi , Ruobing Huang , Jun Cheng , Xiaomeng Li , Wufeng Xue , Dong Ni

Simulation is increasingly being used for generating large labelled datasets in many machine learning problems. Recent methods have focused on adjusting simulator parameters with the goal of maximising accuracy on a validation task, usually…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Harkirat Singh Behl , Atılım Güneş Baydin , Ran Gal , Philip H. S. Torr , Vibhav Vineet