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Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

Machine Learning · Computer Science 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Collecting and annotating datasets for pixel-level semantic segmentation tasks are highly labor-intensive. Data augmentation provides a viable solution by enhancing model generalization without additional real-world data collection.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Huy Che , Dinh-Duy Phan , Duc-Khai Lam

Generative models have been showing potential for producing data in mass. This study explores the enhancement of clinical natural language processing performance by utilizing synthetic data generated from advanced language models. Promising…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Jack Gallifant , Marco Guevara , Yanjun Gao , Majid Afshar , Timothy Miller , Dmitriy Dligach , Danielle S. Bitterman

This survey reviews how large language models (LLMs) are transforming synthetic training data generation in both natural language and code domains. By producing artificial but task-relevant examples, these models can significantly augment…

Computation and Language · Computer Science 2025-11-21 Mihai Nadas , Laura Diosan , Andreea Tomescu

Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…

Machine Learning · Computer Science 2023-12-22 Brandon Theodorou , Shrusti Jain , Cao Xiao , Jimeng Sun

Synthetic data are becoming a critical tool for building artificially intelligent systems. Simulators provide a way of generating data systematically and at scale. These data can then be used either exclusively, or in conjunction with real…

Artificial Intelligence · Computer Science 2023-04-07 Daniel McDuff , Theodore Curran , Achuta Kadambi

Generating synthetic tabular health data is challenging, and evaluating their quality is equally, if not more, complex. This systematic review highlights the critical importance of rigorous evaluation of synthetic health data to ensure…

Machine Learning · Computer Science 2026-05-15 Nazia Nafis , Inaki Esnaola , Alvaro Martinez-Perez , Maria-Cruz Villa-Uriol , Venet Osmani

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Generating synthetic text addresses the challenge of data availability in privacy-sensitive domains such as healthcare. This study explores the applicability of synthetic data in real-world medical settings. We introduce MedSyn, a novel…

Computation and Language · Computer Science 2024-09-05 Gleb Kumichev , Pavel Blinov , Yulia Kuzkina , Vasily Goncharov , Galina Zubkova , Nikolai Zenovkin , Aleksei Goncharov , Andrey Savchenko

Over the last three to five years, it has become possible to generate machine learning synthetic data for healthcare-related uses. However, concerns have been raised about potential negative factors associated with the possibilities of…

Evidence-based medicine promises to improve the quality of healthcare by empowering medical decisions and practices with the best available evidence. The rapid growth of medical evidence, which can be obtained from various sources, poses a…

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Deep neural networks have become prevalent in human analysis, boosting the performance of applications, such as biometric recognition, action recognition, as well as person re-identification. However, the performance of such networks scales…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Indu Joshi , Marcel Grimmer , Christian Rathgeb , Christoph Busch , Francois Bremond , Antitza Dantcheva

The emergence of generative AI models has dramatically expanded the availability and use of synthetic data across scientific, industrial, and policy domains. While these developments open new possibilities for data analysis, they also raise…

Machine Learning · Statistics 2026-03-06 Ahmad Abdel-Azim , Ruoyu Wang , Xihong Lin

Deep learning models need a sufficient amount of data in order to be able to find the hidden patterns in it. It is the purpose of generative modeling to learn the data distribution, thus allowing us to sample more data and augment the…

Machine Learning · Computer Science 2024-11-28 José Fernando Núñez , Jamie Arjona , Javier Béjar

Synthetic data is increasingly critical for contact centers, where privacy constraints and data scarcity limit the availability of real conversations. However, generating synthetic dialogues that are realistic and useful for downstream…

Computation and Language · Computer Science 2026-02-17 Rishikesh Devanathan , Varun Nathan , Ayush Kumar

Alongside the growth of generative AI, we are witnessing a surge in the use of synthetic data across all stages of the AI development pipeline. It is now common practice for researchers and practitioners to use one large generative model…

Human-Computer Interaction · Computer Science 2025-05-14 Shivani Kapania , Stephanie Ballard , Alex Kessler , Jennifer Wortman Vaughan

Synthetic data generation creates data based on real-world data using generative models. In health applications, generating high-quality data while maintaining fairness for sensitive attributes is essential for equitable outcomes. Existing…

Machine Learning · Computer Science 2025-06-25 Nitish Nagesh , Ziyu Wang , Amir M. Rahmani

Faced with the challenges of patient confidentiality and scientific reproducibility, research on machine learning for health is turning towards the conception of synthetic medical databases. This article presents a brief overview of…

Clinical Question Answering (QA) systems enable doctors to quickly access patient information from electronic health records (EHRs). However, training these systems requires significant annotated data, which is limited due to the expertise…

Computation and Language · Computer Science 2024-12-09 Fan Bai , Keith Harrigian , Joel Stremmel , Hamid Hassanzadeh , Ardavan Saeedi , Mark Dredze