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Radiation therapy (RT) requires precise dose delivery over multiple fractions, with CT fundamental for treatment planning due to its electron density information. Repeated CT acquisitions impose radiation exposure and logistical burdens,…

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi

Multimodal MR-US registration is critical for prostate cancer diagnosis. However, this task remains challenging due to significant modality discrepancies. Existing methods often fail to align critical boundaries while being overly sensitive…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xudong Ma , Nantheera Anantrasirichai , Stefanos Bolomytis , Alin Achim

Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical…

Accurate dose calculations in proton therapy rely on high-quality CT images. While planning CTs (pCTs) serve as a reference for dosimetric planning, Cone Beam CT (CBCT) is used throughout Adaptive Radiotherapy (ART) to generate sCTs for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 David Vallmanya Poch , Yorick Estievenart , Elnura Zhalieva , Sukanya Patra , Mohammad Yaqub , Souhaib Ben Taieb

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Recently, joint registration and segmentation has been formulated in a deep learning setting, by the definition of joint loss functions. In this work, we investigate joining these tasks at the architectural level. We propose a registration…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Laurens Beljaards , Mohamed S. Elmahdy , Fons Verbeek , Marius Staring

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

Deformable Image Registration (DIR) of MR and CT images is one of the most challenging registration task, due to the inherent structural differences of the modalities and the missing dense ground truth. Recently cycle Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Christine Tanner , Firat Ozdemir , Romy Profanter , Valeriy Vishnevsky , Ender Konukoglu , Orcun Goksel

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

Medical Physics · Physics 2024-11-14 R. M. Winter , O. Engelsen , O. J. Bratting , N. Brekke , J. Sæterstøl , O. Sæther , K. R. Redalen

This paper presents a method to register a pre-operative Computed-Tomography (CT) volume to a sparse set of intra-operative Ultra-Sound (US) slices. In the context of percutaneous renal puncture, the aim is to transfer planning information…

Medical Physics · Physics 2007-06-25 Antoine Leroy , Pierre Mozer , Yohan Payan , Jocelyne Troccaz

Topo-Tomography (TT) is a synchrotron-based X-ray diffraction imaging technique used to characterize grain shape and crystal orientation in polycrystalline samples. This work aims to provide a decisive and fundamental understanding of 3D…

Computational Physics · Physics 2025-10-13 Zheheng Liu , Nicola Vigano , Henry Proudhon , Wolfgang Ludwig

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Medical image registration is a fundamental task in medical image analysis, enabling the alignment of images from different modalities or time points. However, intensity inconsistencies and nonlinear tissue deformations pose significant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Eytan Kats , Christoph Grossbroehmer , Ziad Al-Haj Hemidi , Fenja Falta , Wiebke Heyer , Mattias P. Heinrich

Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…

Estimating displacement vector field via a cost volume computed in the feature space has shown great success in image registration, but it suffers excessive computation burdens. Moreover, existing feature descriptors only extract local…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zi Li , Lin Tian , Tony C. W. Mok , Xiaoyu Bai , Puyang Wang , Jia Ge , Jingren Zhou , Le Lu , Xianghua Ye , Ke Yan , Dakai Jin

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

The aim of this study was to develop a model to accurately identify corresponding points between organ segmentations of different patients for radiotherapy applications. A model for simultaneous correspondence and interpolation estimation…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Edward G. A. Henderson , Marcel van Herk , Andrew F. Green , Eliana M. Vasquez Osorio

Upright position CT scans make it possible for full-length-body imaging at conditions more relevant to daily situations, but the substantial weight of the upright CT scanners increases the risks to floor's stability and patients'safety.…

Medical Physics · Physics 2023-11-13 Tong Lin , Tianling Lyu , Zhan Wu , Yan Xi , Wentao Zhu , Yang Chen