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In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Purpose: The fusion of transrectal ultrasound (TRUS) and magnetic resonance (MR) images for guiding targeted prostate biopsy has significantly improved the biopsy yield of aggressive cancers. A key component of MR-TRUS fusion is image…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Grant Haskins , Jochen Kruecker , Uwe Kruger , Sheng Xu , Peter A. Pinto , Brad J. Wood , Pingkun Yan

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Zhe Xu , Jie Luo , Jiangpeng Yan , Ritvik Pulya , Xiu Li , William Wells , Jayender Jagadeesan

Reliable 3D-2D alignment between intraoral scan (IOS) models and lateral cephalometric radiographs is critical for orthodontic diagnosis, yet conventional intensity-driven registration methods struggle under real clinical conditions, where…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Yiyi Miao , Taoyu Wu , Ji Jiang , Tong Chen , Zhe Tang , Zhengyong Jiang , Angelos Stefanidis , Limin Yu , Jionglong Su

Purpose: Accurate intraoperative X-ray/CT registration is essential for surgical navigation in orthopedic procedures. However, existing methods struggle with consistently achieving sub-millimeter accuracy, robustness under broad initial…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Roman Flepp , Leon Nissen , Bastian Sigrist , Arend Nieuwland , Nicola Cavalcanti , Philipp Fürnstahl , Thomas Dreher , Lilian Calvet

Head and neck squamous cell carcinoma (HNSCC) has one of the highest rates of recurrence cases among solid malignancies. Recurrence rates can be reduced by improving positive margins localization. Frozen section analysis (FSA) of resected…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Qingyun Yang , Fangjie Li , Jiayi Xu , Zixuan Liu , Sindhura Sridhar , Whitney Jin , Jennifer Du , Jon Heiselman , Michael Miga , Michael Topf , Jie Ying Wu

Ultrasound computed tomography (USCT) is an emerging medical imaging modality that holds great promise for improving human health. Full-waveform inversion (FWI)-based image reconstruction methods account for the relevant wave physics to…

Medical Physics · Physics 2023-10-20 Fu Li , Umberto Villa , Nebojsa Duric , Mark A. Anastasio

Free Point Transformer (FPT) has been proposed as a data-driven, non-rigid point set registration approach using deep neural networks. As FPT does not assume constraints based on point vicinity or correspondence, it may be trained simply…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Zachary MC Baum , Tamas Ungi , Christopher Schlenger , Yipeng Hu , Dean C Barratt

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

The goal of image registration is to establish spatial correspondence between two or more images, traditionally through dense displacement fields (DDFs) or parametric transformations (e.g., rigid, affine, and splines). Rethinking the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-20 Shiqi Huang , Tingfa Xu , Ziyi Shen , Shaheer Ullah Saeed , Wen Yan , Dean Barratt , Yipeng Hu

CBCTs in image-guided radiotherapy provide crucial anatomy information for patient setup and plan evaluation. Longitudinal CBCT image registration could quantify the inter-fractional anatomic changes. The purpose of this study is to propose…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Huiqiao Xie , Yang Lei , Yabo Fu , Tonghe Wang , Justin Roper , Jeffrey D. Bradley , Pretesh Patel , Tian Liu , Xiaofeng Yang

The rigid registration of aortic Digital Subtraction Angiography (DSA) and Computed Tomography Angiography (CTA) can provide 3D anatomical details of the vasculature for the interventional surgical treatment of conditions such as aortic…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Wentao Liu , Bowen Liang , Weijin Xu , Tong Tian , Qingsheng Lu , Xipeng Pan , Haoyuan Li , Siyu Tian , Huihua Yang , Ruisheng Su

Deformable image registration (DIR) is a crucial and challenging technique for aligning anatomical structures in medical images and is widely applied in diverse clinical applications. However, existing approaches often struggle to capture…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Shayan Kebriti , Shahabedin Nabavi , Ali Gooya

Registration is widely used in image-guided therapy and image-guided surgery to estimate spatial correspondences between organs of interest between planning and treatment images. However, while high-quality computed tomography (CT) images…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Lin Tian , Connor Puett , Peirong Liu , Zhengyang Shen , Stephen R. Aylward , Yueh Z. Lee , Marc Niethammer

The deployment of artificial intelligence in medical imaging is hindered by high computational complexity and resource-intensive processing of volumetric data. Although chest computed tomography (CT) volumes offer richer diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Shadid Yousuf , S. M. Mahbubur Rahman , Mohammed Imamul Hassan Bhuiyan

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Contours are used in radiotherapy treatment planning to identify regions to be irradiated with high dose and regions to be spared. Therefore, any contouring uncertainty influences the whole treatment. Even though this is the biggest…

Medical Physics · Physics 2022-04-22 Eliana Vásquez Osorio , Jane Shortall , Jennifer Robbins , Marcel van Herk

The emergence of real-time 3D ultrasound (US) makes it possible to consider image-based tracking of subcutaneous soft tissue targets for computer guided diagnosis and therapy. We propose a 3D transrectal US based tracking system for precise…

Other Computer Science · Computer Science 2008-01-17 Michael Baumann , Pierre Mozer , Vincent Daanen , Jocelyne Troccaz

Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

Medical Physics · Physics 2023-02-22 Xiao Liang , Howard Morgan , Ti Bai , Michael Dohopolski , Dan Nguyen , Steve Jiang

A method was proposed for the point cloud-based registration and image fusion between cardiac single photon emission computed tomography (SPECT) myocardial perfusion images (MPI) and cardiac computed tomography angiograms (CTA). Firstly,…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Shaojie Tang , Penpen Miao , Xingyu Gao , Yu Zhong , Dantong Zhu , Haixing Wen , Zhihui Xu , Qiuyue Wei , Hongping Yao , Xin Huang , Rui Gao , Chen Zhao , Weihua Zhou