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Reactive molecular dynamics simulations are computationally demanding. Reaching spatial and temporal scales where interesting scientific phenomena can be observed requires efficient and scalable implementations on modern hardware. In this…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-26 Hasan Metin Aktulga , Christopher Knight , Paul Coffman , Kurt A. O'Hearn , Tzu-Ray Shan , Wei Jiang

This paper presents a lightweight, open-source and high-performance python package for solving peridynamics problems in solid mechanics. The development of this solver is motivated by the need for fast analysis tools to achieve the large…

Software Engineering · Computer Science 2021-09-15 B. Boys , T. J. Dodwell , M. Hobbs , M. Girolami

We present a highly scalable Monte Carlo (MC) three-dimensional photon transport simulation platform designed for heterogeneous computing systems. Through the development of a massively parallel MC algorithm using the Open Computing…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-06 Leiming Yu , Fanny Nina-Paravecino , David Kaeli , Qianqian Fang

The High Energy Physics (HEP) experiments, such as those at the Large Hadron Collider (LHC), traditionally consume large amounts of CPU cycles for detector simulations and data analysis, but rarely use compute accelerators such as GPUs. As…

High Energy Physics - Experiment · Physics 2022-03-17 Zhihua Dong , Heather Gray , Charles Leggett , Meifeng Lin , Vincent R. Pascuzzi , Kwangmin Yu

Molecular dynamics (MD) simulations employing classical force fields constitute the cornerstone of contemporary atomistic modeling in chemistry, biology, and materials science. However, the predictive power of these simulations is only as…

Chemical Physics · Physics 2018-09-26 Stefan Chmiela , Huziel E. Sauceda , Klaus-Robert Müller , Alexandre Tkatchenko

Modern computer systems typically conbine multicore CPUs with accelerators like GPUs for inproved performance and energy efficiency. However, these sys- tems suffer from poor performance portability, code tuned for one device must be…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-05-23 Thomas L. Falch , Anne C. Elster

In the quest for highest performance in scientific computing, we present a novel framework that relies on high-bandwidth communication between GPUs in a compute cluster. The framework offers linear scaling of performance for explicit…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-16 Martin Rose , Simon Homes , Lukas Ramsperger , Jose Gracia , Christoph Niethammer , Jadran Vrabec

High-level scripting languages are in many ways polar opposites to GPUs. GPUs are highly parallel, subject to hardware subtleties, and designed for maximum throughput, and they offer a tremendous advance in the performance achievable for a…

Software Engineering · Computer Science 2013-04-23 Andreas Klöckner , Nicolas Pinto , Bryan Catanzaro , Yunsup Lee , Paul Ivanov , Ahmed Fasih

MiMiC is a framework for performing multiscale simulations in which loosely coupled external programs describe individual subsystems at different resolutions and levels of theory. To make it highly efficient and flexible, we adopt an…

Micro-macro models provide a powerful tool to study the relationship between microscale mechanisms and emergent macroscopic behavior. However, the detailed microscopic modeling may require tracking and evolving a high-dimensional…

Computational Physics · Physics 2019-08-13 Steven Cook , Tamar Shinar

AI applications increasingly run on fast-evolving, heterogeneous hardware to maximize performance, but general-purpose libraries lag in supporting these features. Performance-minded programmers often build custom communication stacks that…

Structured Cartesian grids are a fundamental component in numerical simulations. Although these grids facilitate straightforward discretization schemes, their na\"{i}ve use in sparse domains leads to excessive memory overhead and…

Computational Engineering, Finance, and Science · Computer Science 2025-12-15 Fan Gu , Xiangyu Hu

The performance of biomolecular molecular dynamics simulations has steadily increased on modern high performance computing resources but acceleration of the analysis of the output trajectories has lagged behind so that analyzing simulations…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-31 Mahzad Khoshlessan , Ioannis Paraskevakos , Geoffrey C. Fox , Shantenu Jha , Oliver Beckstein

We introduce JAX MD, a software package for performing differentiable physics simulations with a focus on molecular dynamics. JAX MD includes a number of physics simulation environments, as well as interaction potentials and neural networks…

Computational Physics · Physics 2020-12-04 Samuel S. Schoenholz , Ekin D. Cubuk

This survey discusses recent advancements in SYCL compiler implementations, one of the crucial aspects of compiler construction for heterogeneous computing systems. We explore the transition from traditional compiler construction, from…

Systems and Control · Electrical Eng. & Systems 2026-02-25 Huy Trinh

No area of computing is hungrier for performance than High Performance Computing (HPC), the demands of which continue to be a major driver for processor performance and adoption of accelerators, and also advances in memory, storage, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-18 Pablo Ouro , Unai Lopez-Novoa , Martyn Guest

The field of structural bioinformatics has seen significant advances with the use of Molecular Dynamics (MD) simulations of biological systems. The MD methodology has allowed to explain and discover molecular mechanisms in a wide range of…

The implementation of Molecular Dynamics (MD) on FPGAs has received substantial attention. Previous work, however, has consisted of either proof-of-concept implementations of components, usually the range-limited force; full systems, but…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-15 Chen Yang , Tong Geng , Tianqi Wang , Rushi Patel , Qingqing Xiong , Ahmed Sanaullah , Jiayi Sheng , Charles Lin , Vipin Sachdeva , Woody Sherman , Martin C. Herbordt

Fast-evolving machine learning (ML) workloads have increasing requirements for networking. However, host network transport on RDMA NICs is hard to evolve, causing problems for ML workloads. For example, single-path RDMA traffic is prone to…

Networking and Internet Architecture · Computer Science 2025-08-06 Yang Zhou , Zhongjie Chen , Ziming Mao , ChonLam Lao , Shuo Yang , Pravein Govindan Kannan , Jiaqi Gao , Yilong Zhao , Yongji Wu , Kaichao You , Fengyuan Ren , Zhiying Xu , Costin Raiciu , Ion Stoica

Energy awareness and efficiency policies are gaining more attention, over pure performance (time-to-solution) Key Performance Indicators (KPIs) when comparing the possibilities offered by accelerated systems. But in a field such as…

Instrumentation and Methods for Astrophysics · Physics 2025-08-21 Salvatore Cielo , Alexander Pöppl , Ivan Pribec