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Simulations based on particle methods, such as Smoothed Particle Hydrodynamics (SPH), are known to be computationally demanding. While such methods have for long been executed in parallel on multi-core CPUs, in recent years the increasing…

Computational Engineering, Finance, and Science · Computer Science 2026-03-18 Xiangyu Hu , Alberto Guarnieri

With the advent of high-performance computing techniques, the data for analysis has grown significantly. Here, graphic processing unit (GPU) based program kernels are discussed to exploit parallelism in the analysis codes specific to…

Computational Physics · Physics 2018-11-07 Gourav Shrivastav , Manish Agarwal

Molecular dynamics (MD) simulation is a powerful computational tool to study the behavior of macromolecular systems. But many simulations of this field are limited in spatial or temporal scale by the available computational resource. In…

Computational Physics · Physics 2010-01-22 Ji Xu , Ying Ren , Wei Ge , Xiang Yu , Xiaozhen Yang , Jinghai Li

Parallel programming models can encourage performance portability by moving the responsibility for work assignment and data distribution from the programmer to a runtime system. However, analyzing the resulting implicit memory allocations,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-14 Fabian Knorr , Philip Salzmann , Peter Thoman , Thomas Fahringer

The Black-Scholes option pricing problem is one of the widely used financial benchmarks. We explore the possibility of developing a high-performance portable code using the SYCL (Data Parallel C++) programming language. We start from a C++…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-11 Elena Panova , Valentin Volokitin , Anton Gorshkov , Iosif Meyerov

High-throughput structure-based screening of drug-like molecules has become a common tool in biomedical research. Recently, acceleration with graphics processing units (GPUs) has provided a large performance boost for molecular docking…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-07 Mathialakan Thavappiragasam , Wael Elwasif , Ada Sedova

In this talk I discuss the general question of the portability of Molecular Dynamics codes for diffusive systems on parallel computers of the APE family. The intrinsic single precision arithmetics of the today available APE platforms does…

Biological Physics · Physics 2009-10-30 G. La Penna , S. Letardi , V. Minicozzi , S. Morante , G. C. Rossi , G. Salina

The evolution of the computing landscape has resulted in the proliferation of diverse hardware architectures, with different flavors of GPUs and other compute accelerators becoming more widely available. To facilitate the efficient use of…

High Energy Physics - Experiment · Physics 2023-04-05 Meifeng Lin , Zhihua Dong , Tianle Wang , Mohammad Atif , Meghna Battacharya , Kyle Knoepfel , Charles Leggett , Brett Viren , Haiwang Yu

OpenCL is a standard for parallel programming of heterogeneous systems. The benefits of a common programming standard are clear; multiple vendors can provide support for application descriptions written according to the standard, thus…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-23 Pekka Jääskeläinen , Carlos Sánchez de La Lama , Erik Schnetter , Kalle Raiskila , Jarmo Takala , Heikki Berg

Similar to other programming models, compilers for SYCL, the open programming model for heterogeneous computing based on C++, would benefit from access to higher-level intermediate representations. The loss of high-level structure and…

Programming Languages · Computer Science 2023-12-21 Ettore Tiotto , Víctor Pérez , Whitney Tsang , Lukas Sommer , Julian Oppermann , Victor Lomüller , Mehdi Goli , James Brodman

Molecular dynamics (MD) simulations and computer-aided drug design (CADD) have advanced substantially over the past two decades, thanks to continuous computer hardware and software improvements. Given these advancements, MD simulations are…

Quantitative Methods · Quantitative Biology 2023-11-29 Mayar Ahmed , Alex M. Maldonado , Jacob D. Durrant

Molecular dynamics (MD) simulation is one of the past decade's most important tools for enabling biology scientists and researchers to explore human health and diseases. However, due to the computation complexity of the MD algorithm, it…

Computational Physics · Physics 2016-11-15 Jason Cong , Zhenman Fang , Hassan Kianinejad , Peng Wei

While parallelism remains the main source of performance, architectural implementations and programming models change with each new hardware generation, often leading to costly application re-engineering. Most tools for performance…

Programming Languages · Computer Science 2022-07-04 William S. Moses , Ivan R. Ivanov , Jens Domke , Toshio Endo , Johannes Doerfert , Oleksandr Zinenko

RUMD is a general purpose, high-performance molecular dynamics (MD) simulation package running on graphical processing units (GPU's). RUMD addresses the challenge of utilizing the many-core nature of modern GPU hardware when simulating…

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

As the interest in FPGA-based accelerators for HPC applications increases, new challenges also arise, especially concerning different programming and portability issues. This paper aims to provide a snapshot of the current state of the FPGA…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-06 Manuel de Castro , Francisco J. andújar , Roberto R. Osorio , Rocío Carratalá-Sáez , Diego R. Llanos

A merge tree is a topological descriptor of a real-valued function. Merge trees are used in visualization and topological data analysis, either directly or as a means to another end: computing a 0-dimensional persistence diagram,…

Computational Geometry · Computer Science 2023-01-31 Arnur Nigmetov , Dmitriy Morozov

Classical molecular dynamics (MD) simulations are important tools in life and material sciences since they allow studying chemical and biological processes in detail. However, the inherent scalability problem of particle-particle…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-14 Michael Schaffner , Luca Benini

Automatically tuning parallel compute kernels allows libraries and frameworks to achieve performance on a wide range of hardware, however these techniques are typically focused on finding optimal kernel parameters for particular input sizes…

Performance · Computer Science 2020-09-01 John Lawson

Next generation High-Energy Physics (HEP) experiments are presented with significant computational challenges, both in terms of data volume and processing power. Using compute accelerators, such as GPUs, is one of the promising ways to…