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Segmentation using deep learning has shown promising directions in medical imaging as it aids in the analysis and diagnosis of diseases. Nevertheless, a main drawback of deep models is that they require a large amount of pixel-level labels,…

Computer Vision and Pattern Recognition · Computer Science 2020-04-08 Sukesh Adiga , Jose Dolz , Herve Lombaert

Although unprecedented sensitivity and specificity values are reported, recent glaucoma detection deep learning models lack in decision transparency. Here, we propose a methodology that advances explainable deep learning in the field of…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Ruben Hemelings , Bart Elen , João Barbosa-Breda , Matthew B. Blaschko , Patrick De Boever , Ingeborg Stalmans

This paper presents a comparative analysis of deep learning strategies for detecting hypertensive retinopathy from fundus images, a central task in the HRDC challenge~\cite{qian2025hrdc}. We investigate three distinct approaches: a custom…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yanqiao Zhu

Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Huazhu Fu , Jun Cheng , Yanwu Xu , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Over the past few years, there has been growing interest in developing a broad, universal, and general-purpose computer vision system. Such systems have the potential to address a wide range of vision tasks simultaneously, without being…

Computer Vision and Pattern Recognition · Computer Science 2023-10-13 Feng Lin , Wenze Hu , Yaowei Wang , Yonghong Tian , Guangming Lu , Fanglin Chen , Yong Xu , Xiaoyu Wang

Accurately segmenting blood vessels in retinal fundus images is crucial in the early screening, diagnosing, and evaluating some ocular diseases, yet it poses a nontrivial uncertainty for the segmentation task due to various factors such as…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yuanyuan Peng , Pengpeng Luan , Zixu Zhang

Label smoothing loss is a widely adopted technique to mitigate overfitting in deep neural networks. This paper studies label smoothing from the perspective of Neural Collapse (NC), a powerful empirical and theoretical framework which…

Machine Learning · Computer Science 2025-09-30 Li Guo , George Andriopoulos , Zifan Zhao , Shuyang Ling , Zixuan Dong , Keith Ross

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Norsang Lama , R. Joe Stanley , Anand Nambisan , Akanksha Maurya , Jason Hagerty , William V. Stoecker

Recent research in the field of computer vision strongly focuses on deep learning architectures to tackle image processing problems. Deep neural networks are often considered in complex image processing scenarios since traditional computer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Marcel P. Schilling , Luca Rettenberger , Friedrich Münke , Haijun Cui , Anna A. Popova , Pavel A. Levkin , Ralf Mikut , Markus Reischl

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos

Early detection of retinal diseases is one of the most important means of preventing partial or permanent blindness in patients. In this research, a novel multi-label classification system is proposed for the detection of multiple retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 M. A. Rodriguez , H. AlMarzouqi , P. Liatsis

Glaucoma, a leading cause of irreversible blindness, necessitates early detection for accurate and timely intervention to prevent irreversible vision loss. In this study, we present a novel deep learning framework that leverages the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-05 Mona Ashtari-Majlan , David Masip

This study introduces the Hybrid Multi-modal VGG (HM-VGG) model, a cutting-edge deep learning approach for the early diagnosis of glaucoma. The HM-VGG model utilizes an attention mechanism to process Visual Field (VF) data, enabling the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Junliang Du , Yiru Cang , Tong Zhou , Jiacheng Hu , Weijie He

Diabetic retinopathy (DR) is a primary cause of blindness in working-age people worldwide. About 3 to 4 million people with diabetes become blind because of DR every year. Diagnosis of DR through color fundus images is a common approach to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-27 Qilei Chen , Ping Liu , Jing Ni , Yu Cao , Benyuan Liu , Honggang Zhang

Deep learning approaches often require huge datasets to achieve good generalization. This complicates its use in tasks like image-based medical diagnosis, where the small training datasets are usually insufficient to learn appropriate data…

Computer Vision and Pattern Recognition · Computer Science 2021-02-12 Roberto Vega , Pouneh Gorji , Zichen Zhang , Xuebin Qin , Abhilash Rakkunedeth Hareendranathan , Jeevesh Kapur , Jacob L. Jaremko , Russell Greiner

Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Alireza Tavakkoli , Stewart Lee Zuckerbrod

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Glaucoma causes irreversible vision loss due to damage to the optic nerve, and there is no cure for glaucoma.OCT imaging modality is an essential technique for assessing glaucomatous damage since it aids in quantifying fundus structures. To…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Huihui Fang , Fei Li , Huazhu Fu , Junde Wu , Xiulan Zhang , Yanwu Xu

Deep learning-based melanoma classification with dermoscopic images has recently shown great potential in automatic early-stage melanoma diagnosis. However, limited by the significant data imbalance and obvious extraneous artifacts, i.e.,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 ChengHui Yu , MingKang Tang , ShengGe Yang , MingQing Wang , Zhe Xu , JiangPeng Yan , HanMo Chen , Yu Yang , Xiao-Jun Zeng , Xiu Li