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Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Accurate segmentation of the optic disc from a retinal image is vital to extracting retinal features that may be highly correlated with retinal conditions such as glaucoma. In this paper, we propose a deep-learning based approach capable of…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Abdullah Sarhan , Ali Al-KhazÁly , Adam Gorner , Andrew Swift , Jon Rokne , Reda Alhajj , Andrew Crichton

Current methods focusing on medical image segmentation suffer from incorrect annotations, which is known as the noisy label issue. Most medical image segmentation with noisy labels methods utilize either noise transition matrix,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Zicheng Wang , Zhen Zhao , Erjian Guo , Luping Zhou

Deep learning models, especially convolutional neural networks, have achieved impressive results in medical image classification. However, these models often produce overconfident predictions, which can undermine their reliability in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Kushan Choudhury , Shubhrodeep Roy , Ankur Chanda , Shubhajit Biswas , Somenath Kuiry

Our research is motivated by the urgent global issue of a large population affected by retinal diseases, which are evenly distributed but underserved by specialized medical expertise, particularly in non-urban areas. Our primary objective…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Deependra Singh , Saksham Agarwal , Subhankar Mishra

The automatic diagnosis of various retinal diseases from fundus images is important to support clinical decision-making. However, developing such automatic solutions is challenging due to the requirement of a large amount of human-annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xiaomeng Li , Mengyu Jia , Md Tauhidul Islam , Lequan Yu , Lei Xing

Melanoma is one of the ten most common cancers in the US. Early detection is crucial for survival, but often the cancer is diagnosed in the fatal stage. Deep learning has the potential to improve cancer detection rates, but its…

Computer Vision and Pattern Recognition · Computer Science 2019-05-16 Devansh Bisla , Anna Choromanska , Jennifer A. Stein , David Polsky , Russell Berman

Existing multi-modal approaches primarily focus on enhancing multi-label skin lesion classification performance through advanced fusion modules, often neglecting the associated rise in parameters. In clinical settings, both clinical and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Peng Tang , Tobias Lasser

Retinal vessel segmentation is a fundamental step in screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Robustness is one of the most critical requirements for practical utilization, since the test images…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xu Sun , Huihui Fang , Yehui Yang , Dongwei Zhu , Lei Wang , Junwei Liu , Yanwu Xu

Label smoothing is widely used in deep neural networks for multi-class classification. While it enhances model generalization and reduces overconfidence by aiming to lower the probability for the predicted class, it distorts the predicted…

Machine Learning · Computer Science 2021-10-12 Mohamed Maher , Meelis Kull

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Diabetic Retinopathy (DR) affects individuals with long-term diabetes. Without early diagnosis, DR can lead to vision loss. Fundus photography captures the structure of the retina along with abnormalities indicative of the stage of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anca Mihai , Adrian Groza

Medical image segmentation is crucial in the field of medical imaging, aiding in disease diagnosis and surgical planning. Most established segmentation methods rely on supervised deep learning, in which clean and precise labels are…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Jiahua Dong , Yue Zhang , Qiuli Wang , Ruofeng Tong , Shihong Ying , Shaolin Gong , Xuanpu Zhang , Lanfen Lin , Yen-Wei Chen , S. Kevin Zhou

Acne, a prevalent skin condition, necessitates precise severity assessment for effective treatment. Acne severity grading typically involves lesion counting and global assessment. However, manual grading suffers from variability and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Kirill Prokhorov , Alexandr A. Kalinin

Early and accurate detection of glaucoma is critical to prevent irreversible vision loss. However, existing methods often rely on unimodal data and lack interpretability, limiting their clinical utility. In this paper, we present GlaBoost,…

Machine Learning · Computer Science 2025-08-07 Cheng Huang , Weizheng Xie , Karanjit Kooner , Tsengdar Lee , Jui-Kai Wang , Jia Zhang

The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Abdullah Sarhan , Jon Rokne , Reda Alhajj , Andrew Crichton

The emergence of Large Language Models (LLMs) presents unprecedented opportunities to revolutionize medical contrastive vision-language pre-training. In this paper, we show how LLMs can facilitate large-scale supervised pre-training,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yingtai Li , Haoran Lai , Xiaoqian Zhou , Shuai Ming , Wenxin Ma , Wei Wei , Shaohua Kevin Zhou

This research work reveals the strengths of intertwining a deep custom convolutional neural network with a disruptive Vision Transformer, both fused together with a radical Cross-Attention module. Here, two high-yielding datasets for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Ramanathan Swaminathan

Training medical image analysis models requires large amounts of expertly annotated data which is time-consuming and expensive to obtain. Images are often accompanied by free-text radiology reports which are a rich source of information. In…

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