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Understanding the relationship between nerve anatomy and the functional outcomes of electrical stimulation is critical for optimizing neural interface design. In this study, we conducted acute experiments on four pigs in which epineural…

Signal Processing · Electrical Eng. & Systems 2025-10-06 Jonathan Baum , Chamot-Nonin Manon , Oppelt Vera , David Guiraud , Christine Azevedo Coste , Thomas Guiho

Despite recent advances in brain research, understanding the various signals for pain and pain intensities in the brain cortex is still a complex task due to temporal and spatial variations of brain hemodynamics. In this paper we have…

Neurons and Cognition · Quantitative Biology 2015-07-28 Raul Fernandez Rojas , Xu Huang , Keng Liang Ou , Dat Tran , Sheikh Md. Rabiul Islam

This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

Biological Physics · Physics 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

Neuronal excitability is known to be affected by transcranial electrical stimulation. However, due to the existence of both excitatory and inhibitory neurons in the cortex, the mechanism of neuronal excitability shift is still not clear.…

Neurons and Cognition · Quantitative Biology 2019-08-23 Jiahui Wang , Hao Wang , Xin Yuan Thow , Nitish V. Thakor

Peripheral Nerve Stimulation (PNS) constrains the clinical performance of Magnetic Resonance and Particle Imaging (MRI and MPI) systems. Extensive magneto-stimulation studies have been carried out recently in the field of MPI, where typical…

High density neurostimulation systems are coming to market to help spinal cord injury patients by stimulating and recording neuromuscular function. However, the parameter space that these systems have to explore is exceedingly large, and…

Signal Processing · Electrical Eng. & Systems 2021-12-06 Dhruv Pai , Mentor Kip Ludwig

The purpose of this paper is to investigate experimental and numerical dynamic responses of a preloaded vibro-impacting Hertzian contact under sinusoidal excitation. Dynamic response under random excitation is analysed in the second part of…

Classical Physics · Physics 2016-08-14 Emmanuel Rigaud , Joël Perret-Liaudet

Neuronal brain activity in response to repeated stimuli can be perceived using functional magnetic resonance imaging (fMRI). In this paper, we develop a statistical model for fMRI data that estimates both the associated haemodynamic…

Applications · Statistics 2015-01-26 Christopher J. Brignell , William J. Browne , Ian L. Dryden , Susan T. Francis

We study the response of a Hodgkin-Huxley neuron stimulated by a periodic sequence of conductance pulses arriving through the synapse in the high frequency regime. In addition to the usual excitation threshold there is a smooth crossover…

Biological Physics · Physics 2010-04-08 L. S. Borkowski

The objective of this work was to determine whether application of subthreshold currents to the peripheral nerve increases the excitability of the underlying nerve fibres, and how this increased excitability would alter neural activity as…

Neurons and Cognition · Quantitative Biology 2019-12-06 James Hope , Narrendar Ravi Chandra , Frederique Vanholsbeeck , Andrew McDaid

Acute psychological stress occurs in a wide range of everyday contexts, including transportation, occupational settings, and physical activity, where its reliable detection could enable adaptive system responses and support human…

Human-Computer Interaction · Computer Science 2026-05-18 Esther Bosch

We analyze the effects of spatially extended periodic forcing on the dynamics of one-dimensional excitation waves. Entrainment of unstable primary waves has been studied numerically for different amplitudes and frequencies of additional…

Chaotic Dynamics · Physics 2011-06-03 Joseph M. Starobin , Vivek Varadarajan

The textbook picture of nerve activity is that of a propagating voltage pulse driven by electrical currents through ion channel proteins, which are gated by changes in voltage, temperature, pressure or by drugs. All function is directly…

Biological Physics · Physics 2022-11-24 Thomas Heimburg

The objective of the present work is to measure postural kinematics and power spectral variation from HD-EEG to assess changes in cortical activity during adaptation and habituation to postural perturbation. To evoke proprioceptive postural…

We investigate the relationship between the blood flow velocities (BFV) in the middle cerebral arteries and beat-to-beat blood pressure (BP) recorded from a finger in healthy and post-stroke subjects during the quasi-steady state after…

Biological Physics · Physics 2007-05-23 Zhi Chen , Kun Hu , H. Eugene Stanley , Vera Novak , Plamen Ch. Ivanov

We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states. This EP data…

Neurons and Cognition · Quantitative Biology 2021-12-06 Martin G. Frasch , Bernd Walter , Christoph Anders , Reinhard Bauer

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Medical Physics · Physics 2019-03-11 Andrea Saglietto , Stefania Scarsoglio , Luca Ridolfi , Fiorenzo Gaita , Matteo Anselmino

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

Other Quantitative Biology · Quantitative Biology 2016-03-08 Erich W. Schmid

Focused ultrasound spinal cord neuromodulation studies have demonstrated spinal cord neuromodulation in small animals. The safe and efficacious translation of these approaches to human scale requires an understanding of ultrasound…

Medical Physics · Physics 2024-02-23 Rui Xu , Sven Bestmann , Bradley E. Treeby , Eleanor Martin
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