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Large Language Models (LLMs) hold great promise to revolutionize current clinical systems for their superior capacities on medical text processing tasks and medical licensing exams. Meanwhile, traditional ML models such as SVM and XGBoost…

Computation and Language · Computer Science 2024-11-12 Canyu Chen , Jian Yu , Shan Chen , Che Liu , Zhongwei Wan , Danielle Bitterman , Fei Wang , Kai Shu

Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address…

Computation and Language · Computer Science 2023-10-24 Junling Liu , Peilin Zhou , Yining Hua , Dading Chong , Zhongyu Tian , Andrew Liu , Helin Wang , Chenyu You , Zhenhua Guo , Lei Zhu , Michael Lingzhi Li

As large language models (LLMs) become increasingly integrated into clinical decision-making, ensuring transparent and trustworthy reasoning is essential. However, existing evaluation strategies of LLMs' medical reasoning capability either…

Large language models (LLMs) have performed well in providing general and extensive health suggestions in single-turn conversations, exemplified by systems such as ChatGPT, ChatGLM, ChatDoctor, DoctorGLM, and etc. However, the limited…

Computation and Language · Computer Science 2023-12-05 Yirong Chen , Zhenyu Wang , Xiaofen Xing , huimin zheng , Zhipei Xu , Kai Fang , Junhong Wang , Sihang Li , Jieling Wu , Qi Liu , Xiangmin Xu

The paper introduces a framework for the evaluation of the encoding of factual scientific knowledge, designed to streamline the manual evaluation process typically conducted by domain experts. Inferring over and extracting information from…

Computation and Language · Computer Science 2024-10-21 Magdalena Wysocka , Oskar Wysocki , Maxime Delmas , Vincent Mutel , Andre Freitas

Large language models (LLMs) have shown impressive performance on reasoning benchmarks like math and logic. While many works have largely assumed well-defined tasks, real-world queries are often underspecified and only solvable by acquiring…

Artificial Intelligence · Computer Science 2025-10-28 Belinda Z. Li , Been Kim , Zi Wang

Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…

Computation and Language · Computer Science 2025-09-24 Saksham Khatwani , He Cheng , Majid Afshar , Dmitriy Dligach , Yanjun Gao

Large Multimodal Models (LMMs) exhibit impressive cross-modal understanding and reasoning abilities, often assessed through multiple-choice questions (MCQs) that include an image, a question, and several options. However, many benchmarks…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Jinsheng Huang , Liang Chen , Taian Guo , Fu Zeng , Yusheng Zhao , Bohan Wu , Ye Yuan , Haozhe Zhao , Zhihui Guo , Yichi Zhang , Jingyang Yuan , Wei Ju , Luchen Liu , Tianyu Liu , Baobao Chang , Ming Zhang

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

Computation and Language · Computer Science 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

While large language models (LLMs) have demonstrated impressive capabilities across various natural language processing tasks by acquiring rich factual knowledge from their broad training data, their ability to synthesize and logically…

Computation and Language · Computer Science 2024-07-31 Tianshi Zheng , Jiaxin Bai , Yicheng Wang , Tianqing Fang , Yue Guo , Yauwai Yim , Yangqiu Song

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

Since the release of ChatGPT and GPT-4, large language models (LLMs) and multimodal large language models (MLLMs) have attracted widespread attention for their exceptional capabilities in understanding, reasoning, and generation,…

Computation and Language · Computer Science 2024-12-31 Hanguang Xiao , Feizhong Zhou , Xingyue Liu , Tianqi Liu , Zhipeng Li , Xin Liu , Xiaoxuan Huang

Multiple-choice questions (MCQs) are widely used in the evaluation of large language models (LLMs) due to their simplicity and efficiency. However, there are concerns about whether MCQs can truly measure LLM's capabilities, particularly in…

Computation and Language · Computer Science 2024-05-24 Wangyue Li , Liangzhi Li , Tong Xiang , Xiao Liu , Wei Deng , Noa Garcia

Large Language Models (LLMs) have demonstrated significant potential in handling specialized tasks, including medical problem-solving. However, most studies predominantly focus on English-language contexts. This study introduces a novel…

Computation and Language · Computer Science 2025-09-15 Łukasz Grzybowski , Jakub Pokrywka , Michał Ciesiółka , Jeremi I. Kaczmarek , Marek Kubis

Recent advancements in Large Language Models (LLMs) have demonstrated their potential in delivering accurate answers to questions about world knowledge. Despite this, existing benchmarks for evaluating LLMs in healthcare predominantly focus…

Computation and Language · Computer Science 2024-06-18 Zheheng Luo , Chenhan Yuan , Qianqian Xie , Sophia Ananiadou

Large language models (LLMs), such as ChatGPT, are prone to generate hallucinations, i.e., content that conflicts with the source or cannot be verified by the factual knowledge. To understand what types of content and to which extent LLMs…

Computation and Language · Computer Science 2023-10-24 Junyi Li , Xiaoxue Cheng , Wayne Xin Zhao , Jian-Yun Nie , Ji-Rong Wen

Multiple Choice Question (MCQ) tests are among the most used methods for evaluating large language models (LLMs). Besides checking the correctness of the selected answer, evaluations often consider the model's confidence through the…

Computation and Language · Computer Science 2026-05-05 Tairan Fu , Javier Conde , Gonzalo Martínez , María Grandury , Pedro Reviriego

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

Large Language Models (LLMs) have demonstrated remarkable success in diverse natural language processing (NLP) tasks in general domains. However, LLMs sometimes generate responses with the hallucination about medical facts due to limited…

Computation and Language · Computer Science 2025-01-14 Haochun Wang , Sendong Zhao , Zewen Qiang , Zijian Li , Nuwa Xi , Yanrui Du , MuZhen Cai , Haoqiang Guo , Yuhan Chen , Haoming Xu , Bing Qin , Ting Liu

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…