Large Language Models (LLMs) have demonstrated remarkable success in diverse natural language processing (NLP) tasks in general domains. However, LLMs sometimes generate responses with the hallucination about medical facts due to limited domain knowledge. Such shortcomings pose potential risks in the utilization of LLMs within medical contexts. To address this challenge, we propose knowledge-tuning, which leverages structured medical knowledge bases for the LLMs to grasp domain knowledge efficiently and facilitate reliable response generation. We also release cMedKnowQA, a Chinese medical knowledge question-answering dataset constructed from medical knowledge bases to assess the medical knowledge proficiency of LLMs. Experimental results show that the LLMs which are knowledge-tuned with cMedKnowQA, can exhibit higher levels of accuracy in response generation compared with vanilla instruction-tuning and offer a new reliable way for the domain adaptation of LLMs.
@article{arxiv.2309.04175,
title = {Knowledge-tuning Large Language Models with Structured Medical Knowledge Bases for Reliable Response Generation in Chinese},
author = {Haochun Wang and Sendong Zhao and Zewen Qiang and Zijian Li and Nuwa Xi and Yanrui Du and MuZhen Cai and Haoqiang Guo and Yuhan Chen and Haoming Xu and Bing Qin and Ting Liu},
journal= {arXiv preprint arXiv:2309.04175},
year = {2025}
}