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Our work is concerned with the generation and targeted design of RNA, a type of genetic macromolecule that can adopt complex structures which influence their cellular activities and functions. The design of large scale and complex…

Biomolecules · Quantitative Biology 2021-02-02 Zichao Yan , William L. Hamilton , Mathieu Blanchette

The deep Convolutional Neural Network (CNN) is the state-of-the-art solution for large-scale visual recognition. Following basic principles such as increasing the depth and constructing highway connections, researchers have manually…

Computer Vision and Pattern Recognition · Computer Science 2017-03-07 Lingxi Xie , Alan Yuille

Semantic segmentation in high resolution remote sensing images is a fundamental and challenging task. Convolutional neural networks (CNNs), such as fully convolutional network (FCN) and SegNet, have shown outstanding performance in many…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Lichao Mou , Xiao Xiang Zhu

Deep learning architectures are showing great promise in various computer vision domains including image classification, object detection, event detection and action recognition. In this study, we investigate various aspects of…

Computer Vision and Pattern Recognition · Computer Science 2016-08-08 Hilal Ergun , Mustafa Sert

Early detection and accurate diagnosis are essential to improving patient outcomes. The use of convolutional neural networks (CNNs) for tumor detection has shown promise, but existing models often suffer from overparameterization, which…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Muhammad Irfan , Anum Nawaz , Riku Klen , Abdulhamit Subasi , Tomi Westerlund , Wei Chen

We propose a novel approach to enhance the discriminability of Convolutional Neural Networks (CNN). The key idea is to build a tree structure that could progressively learn fine-grained features to distinguish a subset of classes, by…

Computer Vision and Pattern Recognition · Computer Science 2017-09-25 Zhenhua Wang , Xingxing Wang , Gang Wang

Many deep learning architectures for semantic segmentation involve a Fully Convolutional Neural Network (FCN) followed by a Conditional Random Field (CRF) to carry out inference over an image. These models typically involve unary potentials…

Computer Vision and Pattern Recognition · Computer Science 2018-05-25 Cristina Mata , Guy Ben-Yosef , Boris Katz

The morphological structure of left ventricle segmented from cardiac magnetic resonance images can be used to calculate key clinical parameters, and it is of great significance to the accurate and efficient diagnosis of cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Han Kang , Defeng Chen

An RNA sequence is a word over an alphabet on four elements $\{A,C,G,U\}$ called bases. RNA sequences fold into secondary structures where some bases match one another while others remain unpaired. Pseudoknot-free secondary structures can…

Data Structures and Algorithms · Computer Science 2018-03-28 Édouard Bonnet , Paweł Rzążewski , Florian Sikora

Three-dimensional volumetric imaging of cells allows for in situ visualization, thus preserving contextual insights into cellular processes. Despite recent advances in machine learning methods, morphological analysis of sub-nuclear…

Quantitative Methods · Quantitative Biology 2022-07-21 Niraj Gupta , Eric J. Roberts , Song Pang , C. Shan Xu , Harald F. Hess , Fan Wu , Abby Dernburg , Danielle Jorgens , Petrus H. Zwart , Vignesh Kasinath

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Predicting protein properties such as solvent accessibility and secondary structure from its primary amino acid sequence is an important task in bioinformatics. Recently, a few deep learning models have surpassed the traditional window…

Machine Learning · Computer Science 2016-05-11 Zeming Lin , Jack Lanchantin , Yanjun Qi

This paper presents a novel convolutional neural network (CNN)-based detector for faster-than-Nyquist (FTN) signaling, introducing structured fixed kernel layers with domain-informed masking to effectively mitigate intersymbol interference…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Osman Tokluoglu , Enver Cavus , Ebrahim Bedeer , Halim Yanikomeroglu

We propose a novel non-rigid image registration algorithm that is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered. Different from most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Hongming Li , Yong Fan

Artificial intelligence (AI) models remain an emerging strategy to accelerate materials design and development. We demonstrate that convolutional neural network (CNN) models can characterize DNA origami nanostructures employed in…

Chemical Physics · Physics 2025-03-17 Xingfei Wei , Qiankun Mo , Chi Chen , Mark Bathe , Rigoberto Hernandez

In this paper, we use a fully convolutional neural network (FCNN) for the segmentation of gliomas from Magnetic Resonance Images (MRI). A fully automatic, voxel based classification was achieved by training a 23 layer deep FCNN on 2-D…

Computer Vision and Pattern Recognition · Computer Science 2017-12-07 Varghese Alex , Mohammed Safwan , Ganapathy Krishnamurthi

Deep learning is an important method for molecular design and exhibits considerable ability to predict molecular properties, including physicochemical, bioactive, and ADME/T (absorption, distribution, metabolism, excretion, and toxicity)…

Molecular Networks · Quantitative Biology 2022-05-10 Hanxuan Cai , Huimin Zhang , Duancheng Zhao , Jingxing Wu , Ling Wang

The convolution operation is a central building block of neural network architectures widely used in computer vision. The size of the convolution kernels determines both the expressiveness of convolutional neural networks (CNN), as well as…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tianyu Ma , Adrian V. Dalca , Mert R. Sabuncu

Deep structured output learning shows great promise in tasks like semantic image segmentation. We proffer a new, efficient deep structured model learning scheme, in which we show how deep Convolutional Neural Networks (CNNs) can be used to…

Computer Vision and Pattern Recognition · Computer Science 2015-09-09 Guosheng Lin , Chunhua Shen , Ian Reid , Anton van den Hengel

We applied pre-defined kernels also known as filters or masks developed for image processing to convolution neural network. Instead of letting neural networks find its own kernels, we used 41 different general-purpose kernels of blurring,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Jay Hoon Jung , Yousun Shin , YoungMin Kwon