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Existing state-of-the-art methods that take a single RNA sequence and predict the corresponding RNA secondary-structure are thermodynamic methods. These predict the most stable RNA structure, but do not consider the process of structure…

Biomolecules · Quantitative Biology 2012-07-26 Jeff R. Proctor , Irmtraud M. Meyer

Ab initio RNA secondary structure predictions have long dismissed helices interior to loops, so-called pseudoknots, despite their structural importance. Here, we report that many pseudoknots can be predicted through long time scales RNA…

Biological Physics · Physics 2009-11-10 A. Xayaphoummine , T. Bucher , F. Thalmann , H. Isambert

Scanning transmission electron microscopy (STEM) is an indispensable tool for atomic-resolution structural analysis for a wide range of materials. The conventional analysis of STEM images is an extensive hands-on process, which limits…

An RNA molecule is structured on several layers. The primary and most obvious structure is its sequence of bases, i.e. a word over the alphabet {A,C,G,U}. The higher structure is a set of one-to-one base-pairings resulting in a…

Data Structures and Algorithms · Computer Science 2007-05-23 Michael Brinkmeier

Deep fully convolutional neural network (FCN) based architectures have shown great potential in medical image segmentation. However, such architectures usually have millions of parameters and inadequate number of training samples leading to…

Computer Vision and Pattern Recognition · Computer Science 2018-01-17 Mahendra Khened , Varghese Alex Kollerathu , Ganapathy Krishnamurthi

We present TT2NE, a new algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus. TT2NE guarantees to find the minimum free energy…

Biomolecules · Quantitative Biology 2010-10-22 Michael Bon , Henri Orland

It is the first step for understanding how RNA structure folds from base sequences that to know how its secondary structure is formed. Traditional energy-based algorithms are short of precision, particularly for non-nested sequences, while…

Quantum Physics · Physics 2023-05-18 Ji Jiang , Qipeng Yan , Ye Li , Min Lu , Ziwei Cui , Menghan Dou , Qingchun Wang , Yu-Chun Wu , Guo-Ping Guo

Most current image super-resolution (SR) methods based on convolutional neural networks (CNNs) use residual learning in network structural design, which favors to effective back propagation and hence improves SR performance by increasing…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Xiaole Zhao , Ying Liao , Tian He , Yulun Zhang , Yadong Wu , Tao Zhang

The convolutional neural network (CNN) is one of the most commonly used architectures for computer vision tasks. The key building block of a CNN is the convolutional kernel that aggregates information from the pixel neighborhood and shares…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Tianyu Ma , Alan Q. Wang , Adrian V. Dalca , Mert R. Sabuncu

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Despite recent advances in multi-scale deep representations, their limitations are attributed to expensive parameters and weak fusion modules. Hence, we propose an efficient approach to fuse multi-scale deep representations, called…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Yu Liu , Yanming Guo , Michael S. Lew

Clear cell renal cell carcinoma (ccRCC) is one of the most common forms of intratumoral heterogeneity in the study of renal cancer. ccRCC originates from the epithelial lining of proximal convoluted renal tubules. These cells undergo…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Shiba Kuanar , Vassilis Athitsos , Dwarikanath Mahapatra , Anand Rajan

In this work, we investigate the value of employing deep learning for the task of wireless signal modulation recognition. Recently in [1], a framework has been introduced by generating a dataset using GNU radio that mimics the imperfections…

Machine Learning · Computer Science 2018-01-08 Xiaoyu Liu , Diyu Yang , Aly El Gamal

Click-Through Rate prediction is an important task in recommender systems, which aims to estimate the probability of a user to click on a given item. Recently, many deep models have been proposed to learn low-order and high-order feature…

Information Retrieval · Computer Science 2019-04-30 Bin Liu , Ruiming Tang , Yingzhi Chen , Jinkai Yu , Huifeng Guo , Yuzhou Zhang

We present a novel approach to neural response prediction that incorporates higher-order operations directly within convolutional neural networks (CNNs). Our model extends traditional 3D CNNs by embedding higher-order operations within the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Simone Azeglio , Victor Calbiague Garcia , Guilhem Glaziou , Peter Neri , Olivier Marre , Ulisse Ferrari

Convolutional Neural Networks (CNNs) have shown strong promise for analyzing scientific data from many domains including particle imaging detectors. However, the challenge of choosing the appropriate network architecture (depth, kernel…

Computer Vision and Pattern Recognition · Computer Science 2020-01-13 Duc Hoang , Jesse Hamer , Gabriel N. Perdue , Steven R. Young , Jonathan Miller , Anushree Ghosh

Carbon fiber and graphene-based nanostructures such as carbon nanotubes (CNTs) and defective structures have extraordinary potential as strong and lightweight materials. A longstanding bottleneck has been lack of understanding and…

Materials Science · Physics 2021-10-26 Qi Zhao , Jordan J. Winetrout , Yanxun Xu , Yusu Wang , Hendrik Heinz

Convolutional Neural Networks (CNNs) are known to be significantly over-parametrized, and difficult to interpret, train and adapt. In this paper, we introduce a structural regularization across convolutional kernels in a CNN. In our…

Computer Vision and Pattern Recognition · Computer Science 2020-09-08 Ze Wang , Xiuyuan Cheng , Guillermo Sapiro , Qiang Qiu

In this paper, we introduce a new image representation based on a multilayer kernel machine. Unlike traditional kernel methods where data representation is decoupled from the prediction task, we learn how to shape the kernel with…

Machine Learning · Statistics 2016-10-26 Julien Mairal

Hyperspectral imagery is rich in spatial and spectral information. Using 3D-CNN can simultaneously acquire features of spatial and spectral dimensions to facilitate classification of features, but hyperspectral image information spectral…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Guandong Li , Chunju Zhang