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Background: Representing biological networks as graphs is a powerful approach to reveal underlying patterns, signatures, and critical components from high-throughput biomolecular data. However, graphs do not natively capture the multi-way…

Network scientists have shown that there is great value in studying pairwise interactions between components in a system. From a linear algebra point of view, this involves defining and evaluating functions of the associated adjacency…

Social and Information Networks · Computer Science 2021-08-25 Francesco Tudisco , Desmond J. Higham

In this work, we propose a novel centrality metric, referred to as star centrality, which incorporates information from the closed neighborhood of a node, rather than solely from the node itself, when calculating its topological importance.…

Quantitative Methods · Quantitative Biology 2018-03-15 Chrysafis Vogiatzis , Mustafa Can Camur

Biological and cellular systems are often modeled as graphs in which vertices represent objects of interest (genes, proteins, drugs) and edges represent relational ties among these objects (binds-to, interacts-with, regulates). This…

Machine Learning · Statistics 2017-03-16 Jose Lugo-Martinez , Predrag Radivojac

Hypergraphs that can depict interactions beyond pairwise edges have emerged as an appropriate representation for modeling polyadic relations in complex systems. With the recent surge of interest in researching hypergraphs, the centrality…

Physics and Society · Physics 2022-08-10 Xiao-Wen Xie , Xiu-Xiu Zhan , Zi-Ke Zhang , Chuang Liu

The relations, rather than the elements, constitute the structure of networks. We therefore develop a systematic approach to the analysis of networks, modelled as graphs or hypergraphs, that is based on structural properties of…

Discrete Mathematics · Computer Science 2020-12-08 Marzieh Eidi , Amirhossein Farzam , Wilmer Leal , Areejit Samal , Jürgen Jost

We introduce a new centrality measure that characterizes the participation of each node in all subgraphs in a network. Smaller subgraphs are given more weight than larger ones, which makes this measure appropriate for characterizing network…

Statistical Mechanics · Physics 2009-11-11 Ernesto Estrada , Juan A. Rodriguez-Velazquez

Complex networks can be used to represent complex systems which originate in the real world. Here we study a transformation of these complex networks into simplicial complexes, where cliques represent the simplices of the complex. We extend…

Social and Information Networks · Computer Science 2017-09-04 Ernesto Estrada , Grant Ross

Identifying the most influential nodes in networked systems is of vital importance to optimize their function and control. Several scalar metrics have been proposed to that effect, but the recent shift in focus towards network structures…

Hypergraphs, capable of representing high-order interactions via hyperedges, have become a powerful tool for modeling real-world biological and social systems. Inherent relationships within these real-world systems, such as the encoding…

Social and Information Networks · Computer Science 2025-05-09 Li Ni , Ziqi Deng , Lin Mu , Lei Zhang , Wenjian Luo , Yiwen Zhang

Graph centrality measures use the structure of a network to quantify central or "important" nodes, with applications in web search, social media analysis, and graphical data mining generally. Traditional centrality measures such as the well…

Social and Information Networks · Computer Science 2021-01-20 Liang Lyu , Brandon Fain , Kamesh Munagala , Kangning Wang

In network science complex systems are represented as a mathematical graphs consisting of a set of nodes representing the components and a set of edges representing their interactions. The framework of networks has led to significant…

Physics and Society · Physics 2022-04-07 Alexandre Bovet , Hernán A. Makse

Molecular interactions have widely been modelled as networks. The local wiring patterns around molecules in molecular networks are linked with their biological functions. However, networks model only pairwise interactions between molecules…

Molecular Networks · Quantitative Biology 2018-09-21 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Identifying central entities and interactions is a fundamental problem in network science. While well-studied for graphs (pairwise relations), many biological and social systems exhibit higher-order interactions best modeled by hypergraphs.…

Physics and Society · Physics 2025-12-02 Jaewan Chun , Fanchen Bu , Yeongho Kim , Atsushi Miyauchi , Francesco Bonchi , Kijung Shin

Groups with complex set intersection relations are a natural way to model a wide array of data, from the formation of social groups to the complex protein interactions which form the basis of biological life. One approach to representing…

Machine Learning · Computer Science 2025-01-15 Sepideh Maleki , Josh Vekhter , Keshav Pingali

A hypergraph is a data structure composed of nodes and hyperedges, where each hyperedge is an any-sized subset of nodes. Due to the flexibility in hyperedge size, hypergraphs represent group interactions (e.g., co-authorship by more than…

Social and Information Networks · Computer Science 2023-06-06 Minyoung Choe , Sunwoo Kim , Jaemin Yoo , Kijung Shin

Link prediction is a key aspect of graph machine learning, with applications as diverse as disease prediction, social network recommendations, and drug discovery. It involves predicting new links that may form between network nodes. Despite…

Machine Learning · Computer Science 2023-09-12 Haohui Lu , Shahadat Uddin

Complex network theory has been used to study complex systems. However, many real-life systems involve multiple kinds of objects . They can't be described by simple graphs. In order to provide complete information of these systems, we…

Physics and Society · Physics 2015-11-10 Jin-Li Guo , Xin-Yun Zhu

Hypergraphs have been a powerful tool to represent higher-order interactions, where hyperedges can connect an arbitrary number of nodes. Quantifying the relative importance of nodes and hyperedges in hypergraphs is a fundamental problem in…

Social and Information Networks · Computer Science 2026-03-03 Qing Xu , Chunmeng Liu , Changjiang Bu , Jihong Shen

While network science has become an indispensable tool for studying complex systems, the conventional use of pairwise links often shows limitations in describing high-order interactions properly. Hypergraphs, where each edge can connect…

Physics and Society · Physics 2024-12-20 Zhao Li , Jing Zhang , Jiqiang Zhang , Guozhong Zheng , Weiran Cai , Li Chen
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