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Currently, it is challenging to investigate aneurismal hemodynamics based on current in-vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we…

Fluid Dynamics · Physics 2024-10-17 Thien-Tam Nguyen , Davina Kasperski , Phat Kim Huynh , Trung Quoc Le , Trung Bao Le

Ultrafast ultrasound localization microscopy (ULM), which has shown promising results in microvascular imaging, overcomes the typical trade-off between resolution and penetration depth. Combining ultrasound contrast agents and high frame…

Signal Processing · Electrical Eng. & Systems 2024-07-02 A. N. Madhavanunni , Niya Mariam Benoy , Mahesh Raveendranatha Panicker , Himanshu Shekhar

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

Row column addressed (RCA) transducers present a promising solution for ultrafast volumetric imaging with a reduced channel count and a large field of view. However, RCA-based 3D imaging is fundamentally limited by severe sidelobe artifacts…

Medical Physics · Physics 2026-04-27 Qiandong Sun , Rui He , Shilin Hou , Jiyan Dai , Kailiang Xu

Background and Purpose: Our purpose was to develop a deep learning angiography (DLA) method to generate 3D cerebral angiograms from a single contrast-enhanced acquisition. Material and Methods: Under an approved IRB protocol 105 3D-DSA…

Image and Video Processing · Electrical Eng. & Systems 2018-01-30 Juan C. Montoya , Yinsheng Li , Charles Strother , Guang-Hong Chen

Ultrasound Localization Microscopy (ULM) offers a cost-effective modality for microvascular imaging by using intravascular contrast agents (microbubbles). However, ULM has a fundamental trade-off between acquisition time and spatial…

Signal Processing · Electrical Eng. & Systems 2021-01-26 Ufuk Soylu , Yoram Bresler

Super-resolution ultrasound imaging relies on the sub-wavelength localization of microbubble contrast agents. By tracking individual microbubbles, the velocity and flow within microvessels can be estimated. However, a 2D super-resolution…

Generating realistic MRIs to accurately predict future changes in the structure of brain is an invaluable tool for clinicians in assessing clinical outcomes and analysing the disease progression at the patient level. However, current…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mattia Litrico , Francesco Guarnera , Mario Valerio Giuffrida , Daniele Ravì , Sebastiano Battiato

Functional ultrasound imaging (fUSI) is a cutting-edge technology that measures changes in cerebral blood volume (CBV) by detecting backscattered echoes from red blood cells moving within its field of view (FOV). It offers high…

Neurons and Cognition · Quantitative Biology 2025-08-20 Jared Deighton , Shan Zhong , Kofi Agyeman , Wooseong Choi , Charles Liu , Darrin Lee , Vasileios Maroulas , Vasileios Christopoulos

In this study, we develop a novel methodology for annotating the brain vasculature using dynamic 4D-CTA head scans. By using multiple time points from dynamic CTA acquisitions, we subtract bone and soft tissue to enhance the visualization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alberto Mario Ceballos-Arroyo , Shrikanth M. Yadav , Chu-Hsuan Lin , Jisoo Kim , Geoffrey S. Young , Lei Qin , Huaizu Jiang

Dynamic and precise measurement of cerebral blood flow velocity is crucial in neuroscience and the diagnosis of cerebrovascular diseases. Traditional color Doppler ultrasound can only measure the velocity component along the ultrasound…

Medical Physics · Physics 2025-04-25 Shaoyuan Yan , Yiming Ding , Guoao Ma , Yapeng Fu , Kailiang Xu , Dean Ta

Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal…

Ultrasound vascular imaging is limited by acoustic diffraction, restricting visualization of microvessels essential for understanding organ function and disease. Label-free super-resolution methods exploiting endogenous red blood cells have…

Vasculature is known to be of key biological significance, especially in the study of cancer. As such, considerable effort has been focused on the automated measurement and analysis of vasculature in medical and pre-clinical images. In…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Russell Bates , Benjamin Irving , Bostjan Markelc , Jakob Kaeppler , Ruth Muschel , Vicente Grau , Julia A. Schnabel

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

Patient-specific hemodynamics assessment could support diagnosis and treatment of neurovascular diseases. Currently, conventional medical imaging modalities are not able to accurately acquire high-resolution hemodynamic information that…

Diffuse Correlation Spectroscopy (DCS) allows the label-free investigation of microvascular dynamics deep within living tissue. However, common implementations of DCS are currently limited to measurement depths of $\sim 1-1.5cm$, which can…

Purpose: To assess whether the three-dimensional (3D) structural configuration of the central retinal vessel trunk and its branches (CRVT&B) could be used as a diagnostic marker for glaucoma. Method: We trained a deep learning network to…

Preterm neonates are highly likely to suffer from ventriculomegaly, a dilation of the Cerebral Ventricular System (CVS). This condition can develop into life-threatening hydrocephalus and is correlated with future neuro-developmental…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Matthieu Martin , Bruno Sciolla , Michaël Sdika , Philippe Quétin , Philippe Delachartre

Phase-contrast magnetic resonance imaging (MRI) provides time-resolved quantification of blood flow dynamics that can aid clinical diagnosis. Long in vivo scan times due to repeated three-dimensional (3D) volume sampling over cardiac phases…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Valery Vishnevskiy , Jonas Walheim , Sebastian Kozerke