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Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

Quantitative Methods · Quantitative Biology 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

The study of neurocognitive tasks requiring accurate localisation of activity often rely on functional Magnetic Resonance Imaging, a widely adopted technique that makes use of a pipeline of data processing modules, each involving a variety…

Computer Vision and Pattern Recognition · Computer Science 2016-10-14 Albert Vilamala , Kristoffer Hougaard Madsen , Lars Kai Hansen

One native source of quality deterioration in medical imaging, and especially in our case optical coherence tomography (OCT), is the turbid biological media in which photon does not take a predictable path and many scattering events would…

Image and Video Processing · Electrical Eng. & Systems 2020-11-26 Ali Alavi

We present a vision simulator device (Katsim), a compact near-eye optical display designed for assessing postoperative corrected vision, preoperative intraocular lens (IOL) assessment, and objective IOL characterization. The system forms a…

Metasurfaces -- ultrathin structures composed of subwavelength optical elements -- have revolutionized light manipulation by enabling precise control over electromagnetic waves' amplitude, phase, polarization, and spectral properties.…

Optics · Physics 2024-11-15 Charles Roques-Carmes , Kai Wang , Yuanmu Yang , Arka Majumdar , Zin Lin

Spectral imaging paves way for various fields and particular in biomedical research. However, spectral imaging mainly depending on spatial or temporal scanning, cannot achieve high temporal, spatial and spectral resolution simultaneously.…

Purpose: The integration of multimodal imaging into operating rooms paves the way for comprehensive surgical scene understanding. In ophthalmic surgery, by now, two complementary imaging modalities are available: operating microscope (OPMI)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Nikolo Rohrmoser , Ghazal Ghazaei , Michael Sommersperger , Nassir Navab

Neural implicit functions have emerged as a powerful representation for surfaces in 3D. Such a function can encode a high quality surface with intricate details into the parameters of a deep neural network. However, optimizing for the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Wang Yifan , Shihao Wu , Cengiz Oztireli , Olga Sorkine-Hornung

Optoacoustic (OA) imaging is a promising modality for quantifying blood oxygen saturation (sO$_2$) in various biomedical applications - in diagnosis, monitoring of organ function or even tumor treatment planning. We present an accurate and…

Medical Physics · Physics 2022-02-04 Thomas Kirchner , Michael Jaeger , Martin Frenz

Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…

Accurate assessment of tissue perfusion is crucial in visceral surgery, especially during anastomosis. Currently, subjective visual judgment is commonly employed in clinical settings. Hyperspectral imaging (HSI) offers a non-invasive,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-16 Stefan Kray , Andreas Schmid , Eric L. Wisotzky , Moritz Gerlich , Sebastian Apweiler , Anna Hilsmann , Thomas Greiner , Peter Eisert , Werner Kneist

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

Hyperspectral imaging (HSI) captures a greater level of spectral detail than traditional optical imaging, making it a potentially valuable intraoperative tool when precise tissue differentiation is essential. Hardware limitations of current…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Charlie Budd , Jianrong Qiu , Oscar MacCormac , Martin Huber , Christopher Mower , Mirek Janatka , Théo Trotouin , Jonathan Shapey , Mads S. Bergholt , Tom Vercauteren

Including the effect of the molecular environment in the numerical modeling of time-resolved electronic spectroscopy remains an important challenge in computational spectroscopy. In this contribution, we present a general approach for the…

Quantum Physics · Physics 2024-12-17 Federico Gallina , Matteo Bruschi , Roberto Cacciari , Barbara Fresch

Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine…

Computational Engineering, Finance, and Science · Computer Science 2019-04-03 K. Miller , G. R. Joldes , G. Bourantas , S. K. Warfield , D. E. Hyde , R. Kikinis , A. Wittek

Hyperspectral imaging (HSI) is an emerging modality in health-care applications for disease diagnosis, tissue assessment and image-guided surgery. Tissue reflectances captured by a HSI camera encode physiological properties including…

Medical Physics · Physics 2019-04-08 Anant S. Vemuri , Sebastian Wirkert , Lena Maier-Hein

Estimation of blood oxygenation with spectroscopic photoacoustic imaging is a promising tool for several biomedical applications. For this method to be quantitative, it relies on an accurate method of the light fluence in the tissue. This…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Geoffrey P. Luke , Kevin Hoffer-Hawlik , Austin C. Van Namen , Ruibo Shang

Deep learning methods can be found in many medical imaging applications. Recently, those methods were applied directly to the RF ultrasound multi-channel data to enhance the quality of the reconstructed images. In this paper, we apply a…

Signal Processing · Electrical Eng. & Systems 2020-11-23 Nissim Peretz , Arie Feuer

Background. Bimanual psychomotor proficiency is fundamental to neurosurgical procedures, yet it remains difficult for trainees to acquire and for educators to objectively evaluate performance. In this study, we investigate the feasibility…

The use of hyperspectral imaging for medical applications is becoming more common in recent years. One of the main obstacles that researchers find when developing hyperspectral algorithms for medical applications is the lack of specific,…