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In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To achieve this, we employ spectral unmixing, allowing to…

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

It has been shown that light speckle fluctuations provide a means for noninvasive measurements of cerebral blood flow index (CBFi). While conventional Diffuse Correlation Spectroscopy (DCS) provides marginal brain sensitivity for CBFi in…

Advanced auditory models are useful in designing signal-processing algorithms for hearing-loss compensation or speech enhancement. Such auditory models provide rich and detailed descriptions of the auditory pathway, and might allow for…

Audio and Speech Processing · Electrical Eng. & Systems 2024-03-18 Peter Leer , Jesper Jensen , Zheng-Hua Tan , Jan Østergaard , Lars Bramsløw

Techniques like speckle holography and shearography are rarely applied due to the complexity of instrument setup and lack of automated result analysis, despite their potential. By simulating speckle interferometric outcomes, we seek to…

Optics · Physics 2025-11-25 Jessica Plassmann , Michael Schuth , Georg von Freymann

Hyperspectral imaging has the potential to improve intraoperative decision making if tissue characterisation is performed in real-time and with high-resolution. Hyperspectral snapshot mosaic sensors offer a promising approach due to their…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Peichao Li , Muhammad Asad , Conor Horgan , Oscar MacCormac , Jonathan Shapey , Tom Vercauteren

Validation of deformable image registration techniques is extremely important, but hard, especially when complex deformations or content mismatch are involved. These complex deformations and content mismatch, for example, occur after the…

Neuromorphic computing hardware enables edge computing and can be implemented in flexible electronics for novel applications. Metal oxide materials are promising candidates for fabricating flexible neuromorphic electronics, but suffer from…

Emerging Technologies · Computer Science 2026-04-08 Benius Dunn , Javier Meza-Arroyo , Armi Tiihonen , Mark Lee , Julia W. P. Hsu

A radio interferometer indirectly measures the intensity distribution of the sky over the celestial sphere. Since measurements are made over an irregularly sampled Fourier plane, synthesising an intensity image from interferometric…

Instrumentation and Methods for Astrophysics · Physics 2014-03-18 Daniel Muscat

The release of large datasets and developments in AI have led to dramatic improvements in decoding methods that reconstruct seen images from human brain activity. We evaluate the prospect of further improving recent decoding methods by…

Neurons and Cognition · Quantitative Biology 2023-12-14 Reese Kneeland , Jordyn Ojeda , Ghislain St-Yves , Thomas Naselaris

Modern imaging techniques for probing brain function, including functional Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging, and magnetoencephalography, generate large data sets with complex content. In this…

Neurons and Cognition · Quantitative Biology 2009-11-10 P. P. Mitra , B. Pesaran

Hyperspectral imaging (HSI) is emerging as a promising novel imaging modality with various potential surgical applications. Currently available cameras, however, suffer from poor integration into the clinical workflow because they require…

We present an optimized conductance-based retina microcircuit simulator which transforms light stimuli into a series of graded and spiking action potentials through photo transduction. We use discrete retinal neuron blocks based on a…

Neurons and Cognition · Quantitative Biology 2020-01-16 Jason K. Eshraghian , Seungbum Baek , Wesley Thio , Yulia Sandamirskaya , Herbert H. C. Iu , Wei D. Lu

We study an optomechhanical device supporting at least three optical modes in the infrared telecommunication band and three mechanical vibration modes. We model the coherent driving of each optical mode, independently of each other, to…

Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging measurements has long been advocated as a figure-of-merit to…

Medical Physics · Physics 2025-01-17 Kaiyan Li , Prabhat Kc , Hua Li , Kyle J. Myers , Mark A. Anastasio , Rongping Zeng

Multispectral photoacoustic (PA) imaging is a prime modality to monitor hemodynamics and changes in blood oxygenation (sO2). Although sO2 changes can be an indicator of brain activity both in normal and in pathological conditions, PA…

Neuromorphic imaging is an emerging technique that imitates the human retina to sense variations in dynamic scenes. It responds to pixel-level brightness changes by asynchronous streaming events and boasts microsecond temporal precision…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Pei Zhang , Shuo Zhu , Chutian Wang , Yaping Zhao , Edmund Y. Lam

Recent developments have created differentiable physics simulators designed for machine learning pipelines that can be accelerated on a GPU. While these can simulate biomechanical models, these opportunities have not been exploited for…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 R. James Cotton

Since the publication of our review article Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments in 2018, the technological and applicational landscape of the use of…

Medical Physics · Physics 2026-03-24 Luca Giannoni , Frédéric Lange , Ilias Tachtsidis

The fundamentals of near infrared spectroscopy (NIRS) are reviewed. This technique allows to measure the oxygenation of the brain tissue. The particular problems involved in detecting regional brain oxygenation (rSO2) are discussed. The…

Biological Physics · Physics 2011-03-30 Alexander Gersten , Jacqueline Perle , Amir Raz , Robert Fried