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Modeling of large-scale research facilities is extremely challenging due to complex physical processes and engineering problems. Here, we adopt a data-driven approach to model the longitudinal phase-space diagnostic beamline at the…

Machine Learning · Computer Science 2021-08-11 Jun Zhu , Ye Chen , Frank Brinker , Winfried Decking , Sergey Tomin , Holger Schlarb

Fluorescence microscopy images contain several channels, each indicating a marker staining the sample. Since many different marker combinations are utilized in practice, it has been challenging to apply deep learning based segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-01-28 Alvaro Gomariz , Raphael Egli , Tiziano Portenier , César Nombela-Arrieta , Orcun Goksel

In surveillance, monitoring and tactical reconnaissance, gathering the right visual information from a dynamic environment and accurately processing such data are essential ingredients to making informed decisions which determines the…

Computer Vision and Pattern Recognition · Computer Science 2016-04-18 Kin Gwn Lore , Adedotun Akintayo , Soumik Sarkar

This paper introduces a new method of data-driven microscope design for virtual fluorescence microscopy. Our results show that by including a model of illumination within the first layers of a deep convolutional neural network, it is…

Image and Video Processing · Electrical Eng. & Systems 2020-04-23 Colin L. Cooke , Fanjie Kong , Amey Chaware , Kevin C. Zhou , Kanghyun Kim , Rong Xu , D. Michael Ando , Samuel J. Yang , Pavan Chandra Konda , Roarke Horstmeyer

Luminescence imaging is invaluable for studying biological and material systems, particularly when advanced protocols that exploit temporal dynamics are employed. However, implementing such protocols often requires custom instrumentation,…

Instrumentation and Detectors · Physics 2025-09-16 Ian Coghill , Alienor Lahlou , Andrea Lodetti , Shizue Matsubara , Johann Boucle , Thomas Le Saux , Ludovic Jullien

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Multi-label image classification presents a challenging task in many domains, including computer vision and medical imaging. Recent advancements have introduced graph-based and transformer-based methods to improve performance and capture…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Ahmad Sajedi , Samir Khaki , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Determining positive/negative samples for object detection is known as label assignment. Here we present an anchor-free detector named AutoAssign. It requires little human knowledge and achieves appearance-aware through a fully…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Benjin Zhu , Jianfeng Wang , Zhengkai Jiang , Fuhang Zong , Songtao Liu , Zeming Li , Jian Sun

This paper addresses the problem of quantifying biomarkers in multi-stained tissues, based on color and spatial information. A deep learning based method that can automatically localize and quantify the cells expressing biomarker(s) in a…

Tissues and Organs · Quantitative Biology 2017-01-02 Fahime Sheikhzadeh , Martial Guillaud , Rabab K. Ward

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

In this paper, we introduce a unique variant of the denoising Auto-Encoder and combine it with the perceptual loss to classify images in an unsupervised manner. The proposed method, called Pseudo Labelling, consists of first applying a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Aymene Mohammed Bouayed , Karim Atif , Rachid Deriche , Abdelhakim Saim

Assessing the quality of bovine satellite cells (BSCs) is essential for the cultivated meat industry, which aims to address global food sustainability challenges. This study aims to develop a label-free method for predicting fluorescence…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Sania Sinha , Aarham Wasit , Won Seob Kim , Jongkyoo Kim , Jiyoon Yi

Time-resolved spectral techniques play an important analysis tool in many contexts, from physical chemistry to biomedicine. Customarily, the label-free detection of analytes is manually performed by experts through the aid of classic…

Machine Learning · Computer Science 2020-11-17 Stefano Rini , Hirotsugu Hiramatsu

Organ transplantation serves as the primary therapeutic strategy for end-stage organ failures. However, allograft rejection is a common complication of organ transplantation. Histological assessment is essential for the timely detection and…

Leukemia is one of the most common and death-threatening types of cancer that threaten human life. Medical data from some of the patient's critical parameters contain valuable information hidden among these data. On this subject, deep…

Machine Learning · Computer Science 2024-01-03 Minoo Sayyadpour , Nasibe Moghaddamniya , Touraj Banirostam

The transducer model trained based on sequence-level criterion requires a lot of memory due to the generation of the large probability matrix. We proposed a lightweight transducer model based on frame-level criterion, which uses the results…

Computation and Language · Computer Science 2024-11-04 Genshun Wan , Mengzhi Wang , Tingzhi Mao , Hang Chen , Zhongfu Ye

Automatic detection and tracking of cells in microscopy images are major applications of computer vision technologies in both biomedical research and clinical practice. Though machine learning methods are increasingly common in these…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Nikomidisz Eftimiu , Michal Kozubek

Correlative light and electron microscopy is a powerful tool to study the internal structure of cells. It combines the mutual benefit of correlating light (LM) and electron (EM) microscopy information. However, the classical approach of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Fengjiao Ma , Rainer Kaufmann , Jaroslaw Sedzicki , Zoltán Cseresnyés , Christoph Dehio , Stephanie Hoeppener , Marc Thilo Figge , Rainer Heintzmann

Deep learning is transforming microscopy, yet models often fail when applied to images from new instruments or acquisition settings. Conventional adversarial domain adaptation (ADDA) retrains entire networks, often disrupting learned…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Kai-Wen K. Yang , Andrew Bai , Alexandra Bermudez , Yunqi Hong , Zoe Latham , Iris Sloan , Michael Liu , Vishrut Goyal , Cho-Jui Hsieh , Neil Y. C. Lin

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta