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The standard model for molecular recognition of an odorant is that receptor sites discriminate by molecular geometry as evidenced that two chiral molecules may smell very differently. However, recent studies of isotopically labeled…

Biological Physics · Physics 2015-06-05 Eric R. Bittner , Adrian Madalan , Arkadiuz Czader , Gregg Roman

The work reported here aims to address the effects of time-dependent parameters and stochasticity on decision-making in biological systems. We achieve this by extending previous studies that resorted to simple normal forms. Yet, we focus…

Quantitative Methods · Quantitative Biology 2018-08-29 Nuno R. Nené , James Rivington , Alexey Zaikin

In complex ecosystems such as microbial communities, there is constant ecological and evolutionary feedback between the residing species and the environment occurring on concurrent timescales. Species respond and adapt to their surroundings…

Populations and Evolution · Quantitative Biology 2023-10-17 Jim Wu , David J. Schwab , Trevor GrandPre

The validity of the dissipative quantum model of olfaction has not been examined yet and therefore the model suffers from the lack of experimental support. Here, we generalize the model and propose a numerical analysis of the dissipative…

Chemical Physics · Physics 2017-01-05 Arash Tirandaz , Farhad Taher Ghahramani , Vahid Salari

Predicting olfactory perception directly from molecular structure is central to fragrance design that plays a role in a wide range of industries, such as perfumery, food and beverage, and health care. Among olfactory attributes, odor…

Chemical Physics · Physics 2026-05-18 Peter Fichtelmann , Julia Westermayr

Even the simplest of animals exhibit behavioral sequences with complex temporal dynamics. Prominent amongst the proposed organizing principles for these dynamics has been the idea of a hierarchy, wherein the movements an animal makes can be…

Biological Physics · Physics 2017-02-08 Gordon J. Berman , William Bialek , Joshua W. Shaevitz

Dynamical emergent patterns of swarms are now fairly well established in nature, and include flocking and rotational states. Recently, there has been great interest in engineering and physics to create artificial self-propelled agents that…

Adaptation and Self-Organizing Systems · Physics 2020-05-20 Ira B Schwartz , Victoria Edwards , Sayomi Kamimoto , Klimka Kasraie , Ioana Triandaf , M. Ani Hsieh , Jason Hindes

Phenotype-switching with and without sensing environment is a ubiquitous strategy of organisms to survive in fluctuating environment. Fitness of a population of organisms with phenotype-switching may be constrained and restricted by hidden…

Populations and Evolution · Quantitative Biology 2016-01-20 Tetsuya J. Kobayashi , Yuki Sughiyama

The circadian clock can adapt itself to external cues, but the molecular mechanisms and regulatory networks governing circadian oscillations' transient adjustments are still largely unknown. Here we consider the specific case of circadian…

Molecular Networks · Quantitative Biology 2023-04-18 Ziyu Zhao , Dae-Sung Hwangbo , Sumit Saurabh , Clark Rosensweig , Ravi Allada , William L. Kath , Rosemary Braun

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak

To make informed decisions in natural environments that change over time, humans must update their beliefs as new observations are gathered. Studies exploring human inference as a dynamical process that unfolds in time have focused on…

Neurons and Cognition · Quantitative Biology 2022-03-03 Arthur Prat-Carrabin , Robert C. Wilson , Jonathan D. Cohen , Rava Azeredo da Silveira

Understanding how molecular structure gives rise to odor perception remains a long-standing challenge, with ongoing debate over whether olfaction is primarily governed by molecular shape, vibrational properties, or their interplay at the…

Materials Science · Physics 2026-04-14 P. Zanineli , E. V. C. Lopes , G. R. Schleder , L. N. Lemos , F. Crasto de Lima , A. Fazzio

We present a novel machine learning architecture for classification suggested by experiments on olfactory systems. The network separates input stimuli, represented as spatially distinct currents, via winnerless competition---a process based…

Biological Physics · Physics 2020-06-18 Jason A. Platt , Anna Miller , Lawson Fuller , Henry D. I. Abarbanel

Friction is ubiquitous in daily life, from nanoscale machines to large engineering components. By probing the intricate interplay between system parameters and frictional behavior, scientists seek to unveil the underlying mechanisms that…

Materials Science · Physics 2025-11-26 Yulong Li , Peter Gumbsch , Christian Greiner

In the principal cells of the insect mushroom body, the Kenyon cells (KC), olfactory information is represented by a spatially and temporally sparse code. Each odor stimulus will activate only a small portion of neurons and each stimulus…

Biological Physics · Physics 2010-07-21 Farzad Farkhooi , Eilif Muller , Martin P. Nawrot

Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

Biological Physics · Physics 2016-12-21 Yoshihiko Hasegawa

Molecular communication (MC) has promising potential and a wide range of applications. However, odor-based communication which is common in nature, has not been sufficiently examined within the context of MC, yet. In this paper, we…

Emerging Technologies · Computer Science 2024-11-01 Fatih E. Bilgen , Ahmet B. Kilic , Ozgur B. Akan

The emergence of periodic oscillations is observed in various complex systems in nature and engineering. Thermoacoustic oscillations in systems comprising turbulent reactive flow exemplify such complexity in the engineering context, where…

The vibrational theory of olfaction was posited to explain subtle effects in the sense of smell inexplicable by models in which molecular structure alone determines an odorant's smell. Amazingly, behavioral and neurophysiological evidence…

Biological Physics · Physics 2019-05-01 Nishattasnim Liza , Enrique P. Blair

The problem of tracking the source of a passive scalar in a turbulent flow is relevant to flying insect behavior and several other applications. Extensive previous work has shown that certain Bayesian strategies, such as "infotaxis," can be…

Fluid Dynamics · Physics 2025-03-07 Robin A. Heinonen , Luca Biferale , Antonio Celani , Massimo Vergassola