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It is shown that metric representation of DNA sequences is one-to-one. By using the metric representation method, suppression of nucleotide strings in the DNA sequences is determined. For a DNA sequence, an optimal string length to display…

Biological Physics · Physics 2007-05-23 Zuo-Bing Wu

Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different. Taking into account long-range correlations…

Soft Condensed Matter · Physics 2015-05-14 A. A. Krokhin , V. M. K. Bagci , F. M. Izrailev , O. V. Usatenko , V. A. Yampol'skii

DNA storage has emerged as an important area of research. The reliability of DNA storage system depends on designing the DNA strings (called DNA codes) that are sufficiently dissimilar. In this work, we introduce DNA codes that satisfy a…

Information Theory · Computer Science 2022-11-28 Krishna Gopal Benerjee , Sourav Deb , Manish K Gupta

The so called long range correlation properties of DNA sequences are studied using the variance analyses of the density distribution of a single or a group of nucleotides in a model independent way. This new method which was suggested…

Biological Physics · Physics 2007-05-23 A. K. Mohanty , A. V. S. S. Narayana Rao

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

One of the central problems in the classification of individual test sequences (e.g. genetic analysis), is that of checking for the similarity of sample test sequences as compared with a set of much longer training sequences. This is done…

Information Theory · Computer Science 2014-06-24 Jacob Ziv

When considering binary strings, it's natural to wonder how many distinct subsequences might exist in a given string. Given that there is an existing algorithm which provides a straightforward way to compute the number of distinct…

Combinatorics · Mathematics 2023-06-22 Yonah Biers-Ariel , Anant Godbole , Elizabeth Kelley

The dominant approach to sequence generation is to produce a sequence in some predefined order, e.g. left to right. In contrast, we propose a more general model that can generate the output sequence by inserting tokens in any arbitrary…

Computation and Language · Computer Science 2019-11-04 Dmitrii Emelianenko , Elena Voita , Pavel Serdyukov

Although the expenses associated with DNA sequencing have been rapidly decreasing, the current cost of sequencing information stands at roughly $120/GB, which is dramatically more expensive than reading from existing archival storage…

Discrete Mathematics · Computer Science 2023-11-30 Daniella Bar-Lev , Omer Sabary , Ryan Gabrys , Eitan Yaakobi

Fabrication of DNA nanostructures primarily follows two fundamental rules. First, DNA oligonucleotides mutually combine by Watson-Crick base pairing rules between complementary base sequences. Second, the geometrical compatibility of the…

Mesoscale and Nanoscale Physics · Physics 2011-06-01 Jihoon Shin , Junghoon Kim , Rashid Amin , Seungjae Kim , Young Hun Kwon , Sung Ha Park

As DNA data storage moves closer to practical deployment, minimizing sequencing coverage depth is essential to reduce both operational costs and retrieval latency. This paper addresses the recently studied Random Access Problem, which…

Information Theory · Computer Science 2026-01-13 Chen Wang , Eitan Yaakobi

The sequence a_1,...,a_m is a common subsequence in the set of permutations S = {p_1,...,p_k} on [n] if it is a subsequence of p_i(1),...,p_i(n) and p_j(1),...,p_j(n) for some distinct p_i, p_j in S. Recently, Beame and Huynh-Ngoc (2008)…

Combinatorics · Mathematics 2009-04-13 Paul Beame , Eric Blais , Dang-Trinh Huynh-Ngoc

Let $(F_n)_{n\ge 1}$ be the Fibonacci sequence. Define $P(F_n): = (\sum_{i=1}^n F_i)_{n\ge 1}$; that is, the function $P$ gives the sequence of partial sums of $(F_n)$. In this paper, we first give an identity involving $P^k(F_n)$, which is…

Combinatorics · Mathematics 2021-06-08 Hung Viet Chu

In the classic sequential testing problem, we are given a system with several components each of which fails with some independent probability. The goal is to identify whether or not some component has failed. When the test costs are…

Data Structures and Algorithms · Computer Science 2025-01-31 Blake Harris , Viswanath Nagarajan , Rayen Tan

Motivation: Low-complexity (LC) DNA sequences are compositionally repetitive sequences that are often associated with spurious homologous matches and variant calling artifacts. While algorithms for identifying LC sequences exist, they…

Genomics · Quantitative Biology 2025-11-18 Heng Li , Brian Li

In DNA-based data storage, DNA codes with biochemical constraints and error correction are designed to protect data reliability. Single-stranded DNA sequences with secondary structure avoidance (SSA) help to avoid undesirable secondary…

Information Theory · Computer Science 2023-07-04 Shu Liu , Chaoping Xing , Yaqian Zhang

Most DNA sequencing technologies are based on the shotgun paradigm: many short reads are obtained from random unknown locations in the DNA sequence. A fundamental question, studied in arXiv:1203.6233, is what read length and coverage depth…

Information Theory · Computer Science 2022-02-09 Aditya Narayan Ravi , Alireza Vahid , Ilan Shomorony

A tandem duplication denotes the process of inserting a copy of a segment of DNA adjacent to its original position. More formally, a tandem duplication can be thought of as an operation that converts a string $S = AXB$ into a string $T =…

Computational Complexity · Computer Science 2021-03-16 Ferdinando Cicalese , Nicolò Pilati

The prevalent approach to sequence to sequence learning maps an input sequence to a variable length output sequence via recurrent neural networks. We introduce an architecture based entirely on convolutional neural networks. Compared to…

Computation and Language · Computer Science 2017-07-26 Jonas Gehring , Michael Auli , David Grangier , Denis Yarats , Yann N. Dauphin

The Stern diatomic sequence is closely linked to continued fractions via the Gauss map on the unit interval, which in turn can be understood via systematic subdivisions of the unit interval. Higher dimensional analogues of continued…