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In a data matrix, we may distinguish between cases, each represented by a row vector for a statistical unit, and cells, which correspond to single entries of the data matrix. Recent developments in Robust Statistics have introduced the…

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Valentin Koch , Sophia J. Wagner , Salome Kazeminia , Ece Sancar , Matthias Hehr , Julia Schnabel , Tingying Peng , Carsten Marr

Most research on data discovery has so far focused on improving individual discovery operators such as join, correlation, or union discovery. However, in practice, a combination of these techniques and their corresponding indexes may be…

Databases · Computer Science 2024-12-02 Mahdi Esmailoghli , Christoph Schnell , Renée J. Miller , Ziawasch Abedjan

Cloud computing offers an opportunity to run compute-resource intensive climate models at scale by parallelising model runs such that datasets useful to the exoplanet community can be produced efficiently. To better understand the…

Data commons collate data with cloud computing infrastructure and commonly used software services, tools and applications to create biomedical resources for the large-scale management, analysis, harmonization, and sharing of biomedical…

Genomics · Quantitative Biology 2018-12-27 Robert L. Grossman

Many aspects of macroevolutionary theory and our understanding of biotic responses to global environmental change derive from literature-based compilations of palaeontological data. Existing manually assembled databases are, however,…

Databases · Computer Science 2014-07-23 Shanan E. Peters , Ce Zhang , Miron Livny , Christopher Ré

Structural information of phylogenetic tree topologies plays an important role in phylogenetic inference. However, finding appropriate topological structures for specific phylogenetic inference tasks often requires significant design effort…

Machine Learning · Statistics 2023-02-20 Cheng Zhang

Code evolution is inevitable in modern software development. Changes to third-party APIs frequently break existing code and complicate maintenance, posing practical challenges for developers. While large language models (LLMs) have shown…

Software Engineering · Computer Science 2026-03-10 Jiazhen Kang , Yuchen Lu , Chen Jiang , Jinrui Liu , Tianhao Zhang , Bo Jiang , Ningyuan Sun , Tongtong Wu , Guilin Qi

Effectively leveraging the vast computational resources of modern cloud environments requires expertise spanning multiple technical domains: configuring scientific software with correct parameters and dependencies, navigating thousands of…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-24 Shihan Cheng , Michael A. Laurenzano , Brian Strauch , Timothy A. Ellis , Krish Wadhwani , David A. B. Hyde

An essential part of building a data-driven organization is the ability to handle and process continuous streams of data to discover actionable insights. The explosive growth of interconnected devices and the social Web has led to a large…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-23 Haruna Isah , Farhana Zulkernine

The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

Genomics · Quantitative Biology 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

In the past decade, transcriptome data have become an important component of many phylogenetic studies. Phylogenetic studies now regularly include genes from newly sequenced transcriptomes, as well as publicly available transcriptomes and…

Genomics · Quantitative Biology 2014-01-14 Casey W. Dunn , Mark Howison , Felipe Zapata

Identifying viral pathogens and characterizing their transmission is essential to developing effective public health measures in response to a pandemic. Phylogenetics, though currently the most popular tool used to characterize the likely…

Quantitative Methods · Quantitative Biology 2015-05-28 Anil Raj , Michael Dewar , Gustavo Palacios , Raul Rabadan , Chris H. Wiggins

A phylogeny describes the evolutionary history of an evolving population. Evolutionary search algorithms can perfectly track the ancestry of candidate solutions, illuminating a population's trajectory through the search space. However,…

Neural and Evolutionary Computing · Computer Science 2024-02-05 Alexander Lalejini , Marcos Sanson , Jack Garbus , Matthew Andres Moreno , Emily Dolson

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Increased application of multivariate data in many scientific areas has considerably raised the complexity of analysis and interpretation. Although quite a few approaches have been put forward to address this issue, there is still a gap…

Computation · Statistics 2018-10-30 Elyas Heidari , Vahid Balazadeh-Meresht , Ali Sharifi-Zarchi

Objective. We propose an approach to reason about goals, obstacles, and to select suitable big data solution architecture that satisfy quality goal preferences and constraints of stakeholders at the presence of the decision outcome…

Software Engineering · Computer Science 2020-04-20 Mahdi Fahmideh , Ghassan Beydoun

Delivering effective data analytics is of crucial importance to the interpretation of the multitude of biological datasets currently generated by an ever increasing number of high throughput techniques. Logic programming has much to offer…

Logic in Computer Science · Computer Science 2019-09-19 Nicos Angelopoulos , Jan Wielemaker

Scientific investigations that incorporate next generation sequencing involve analyses of high-dimensional data where the need to organize, collate and interpret the outcomes are pressingly important. Currently, data can be collected at the…

Machine Learning · Statistics 2016-08-01 Stephen T Rush , Christine H Lee , Washington Mio , Peter T Kim

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu