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Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

Computer Vision and Pattern Recognition · Computer Science 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

The drive for reproducibility in the computational sciences has provoked discussion and effort across a broad range of perspectives: technological, legislative/policy, education, and publishing. Discussion on these topics is not new, but…

Quantitative Methods · Quantitative Biology 2018-10-10 Daniel G. Hurley , Joseph Cursons , Matthew Faria , David M. Budden , Vijay Rajagopal , Edmund J. Crampin

We present a visualization tool to exhaustively search and browse through a set of large-scale machine learning datasets. Built on the top of the VizWiz dataset, our dataset browser tool has the potential to support and enable a variety of…

Machine Learning · Computer Science 2019-12-20 Nilavra Bhattacharya , Danna Gurari

The size of web has increased exponentially over the past few years with thousands of documents related to a subject available to the user. With this much amount of information available, it is not possible to take the full advantage of the…

Information Retrieval · Computer Science 2012-11-07 R. K. Roul , S. K. Sahay

Inspired by natural evolutionary processes, Evolutionary Computation (EC) has established itself as a cornerstone of Artificial Intelligence. Recently, with the surge in data-intensive applications and large-scale complex systems, the…

Neural and Evolutionary Computing · Computer Science 2024-04-16 Beichen Huang , Ran Cheng , Zhuozhao Li , Yaochu Jin , Kay Chen Tan

Modern data analytics requires a huge amount of computing power and processes a massive amount of data. At the same time, the underlying computing platform is becoming much more heterogeneous on both hardware and software. Even though…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-13 Zeke Wang , Jie Zhang , Hongjing Huang , Yingtao Li , Xueying Zhu , Mo Sun , Zihan Yang , De Ma , Huajing Tang , Gang Pan , Fei Wu , Bingsheng He , Gustavo Alonso

Information Retrieval systems can be improved by exploiting context information such as user and document features. This article presents a model based on overlapping probabilistic or fuzzy clusters for such features. The model is applied…

Human-Computer Interaction · Computer Science 2011-02-21 Thomas Mandl , Christa Womser-Hacker

Inferring dependencies between complex biological traits while accounting for evolutionary relationships between specimens is of great scientific interest yet remains infeasible when trait and specimen counts grow large. The…

We introduce InfiFusion, an efficient training pipeline designed to integrate multiple domain-specialized Large Language Models (LLMs) into a single pivot model, effectively harnessing the strengths of each source model. Traditional fusion…

Computation and Language · Computer Science 2025-02-18 Zhaoyi Yan , Yiming Zhang , Baoyi He , Yuhao Fu , Qi Zhou , Zhijie Sang , Chunlin Ji , Shengyu Zhang , Fei Wu , Hongxia Yang

Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations. Although current investigations successfully focus on…

Quantitative Methods · Quantitative Biology 2009-09-29 Jérémie Bourdon , Damien Eveillard , Samuel Gabillard , Theo Merle

Large language models (LLMs) have shown remarkable performance across a wide range of applications, often outperforming human experts. However, deploying these gigantic models efficiently for diverse inference use cases requires carefully…

As data-driven methods are becoming pervasive in a wide variety of disciplines, there is an urgent need to develop scalable and sustainable tools to simplify the process of data science, to make it easier to keep track of the analyses being…

Databases · Computer Science 2016-10-18 Hui Miao , Amit Chavan , Amol Deshpande

As metabolomics datasets are becoming larger and more complex, there is an increasing need for model-based data integration and analysis to optimally leverage these data. Dynamical models of metabolism allow for the integration of…

Quantitative Methods · Quantitative Biology 2023-11-29 Polina Lakrisenko , Daniel Weindl

Developing predictive modelling solutions for risk estimation is extremely challenging in health-care informatics. Risk estimation involves integration of heterogeneous clinical sources having different representation from different…

Machine Learning · Computer Science 2016-09-30 Priyanka H U , Vivek R

Cloud computing has become a major approach to help reproduce computational experiments. Yet there are still two main difficulties in reproducing batch based big data analytics (including descriptive and predictive analytics) in the cloud.…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-13 Xin Wang , Pei Guo , Xingyan Li , Aryya Gangopadhyay , Carl E. Busart , Jade Freeman , Jianwu Wang

EpiLearn is a Python toolkit developed for modeling, simulating, and analyzing epidemic data. Although there exist several packages that also deal with epidemic modeling, they are often restricted to mechanistic models or traditional…

Machine Learning · Computer Science 2024-09-10 Zewen Liu , Yunxiao Li , Mingyang Wei , Guancheng Wan , Max S. Y. Lau , Wei Jin

Propagation models are essential for modeling and simulating dynamic processes such as epidemics and information diffusion. However, existing tools struggle to scale to large-scale graphs that emerge across social networks, epidemic…

Social and Information Networks · Computer Science 2026-03-18 Chang Guo , Juyuan Zhang , Chang Su , Tianlong Fan , Linyuan Lü

There is a great concern nowadays regarding alcohol consumption and drug abuse, especially in young people. Analyzing the social environment where these adolescents are immersed, as well as a series of measures determining the alcohol abuse…

Although recent scaling up approaches to training deep neural networks have proven to be effective, the computational intensity of large and complex models, as well as the availability of large-scale datasets, require deep learning…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-21 Bita Hasheminezhad , Shahrzad Shirzad , Nanmiao Wu , Patrick Diehl , Hannes Schulz , Hartmut Kaiser
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