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Molecular representation learning is crucial for the problem of molecular property prediction, where graph neural networks (GNNs) serve as an effective solution due to their structure modeling capabilities. Since labeled data is often…

Machine Learning · Computer Science 2023-09-26 Cameron Diao , Kaixiong Zhou , Zirui Liu , Xiao Huang , Xia Hu

Graph neural networks (GNNs) are shown to be successful in modeling applications with graph structures. However, training an accurate GNN model requires a large collection of labeled data and expressive features, which might be inaccessible…

Machine Learning · Computer Science 2019-06-03 Ziniu Hu , Changjun Fan , Ting Chen , Kai-Wei Chang , Yizhou Sun

Many machine learning (ML) approaches are widely used to generate bioclimatic models for prediction of geographic range of organism as a function of climate. Applications such as prediction of range shift in organism, range of invasive…

Machine Learning · Computer Science 2013-06-19 Maumita Bhattacharya

The increasing adoption of natural language processing (NLP) models across industries has led to practitioners' need for machine learning systems to handle these models efficiently, from training to serving them in production. However,…

Computation and Language · Computer Science 2023-08-17 Lovre Torbarina , Tin Ferkovic , Lukasz Roguski , Velimir Mihelcic , Bruno Sarlija , Zeljko Kraljevic

Multi-task learning (MTL) optimizes several learning tasks simultaneously and leverages their shared information to improve generalization and the prediction of the model for each task. Auxiliary tasks can be added to the main task to…

Machine Learning · Computer Science 2020-07-03 Partoo Vafaeikia , Khashayar Namdar , Farzad Khalvati

Machine learning (ML) has become a commodity in our every-day lives. We routinely ask ML empowered smartphones to suggest lovely food places or to guide us through a strange place. ML methods have also become standard tools in many fields…

Machine Learning · Computer Science 2022-02-01 Alexander Jung

Machine learning (ML) is poised to drive innovations in clinical microbiomics, such as in disease diagnostics and prognostics. However, the successful implementation of ML in these domains necessitates the development of reproducible,…

Genomics · Quantitative Biology 2024-12-02 Natasha K. Dudek , Mariam Chakhvadze , Saba Kobakhidze , Omar Kantidze , Yuriy Gankin

Large Language Models (LLMs), with their remarkable task-handling capabilities and innovative outputs, have catalyzed significant advancements across a spectrum of fields. However, their proficiency within specialized domains such as…

Quantitative Methods · Quantitative Biology 2024-03-05 Yin Fang , Xiaozhuan Liang , Ningyu Zhang , Kangwei Liu , Rui Huang , Zhuo Chen , Xiaohui Fan , Huajun Chen

Explainable ML for molecular toxicity prediction is a promising approach for efficient drug development and chemical safety. A predictive ML model of toxicity can reduce experimental cost and time while mitigating ethical concerns by…

Quantitative Methods · Quantitative Biology 2022-04-15 Bhanushee Sharma , Vijil Chenthamarakshan , Amit Dhurandhar , Shiranee Pereira , James A. Hendler , Jonathan S. Dordick , Payel Das

In this chapter, we provide a brief overview of applying machine learning techniques for clinical prediction tasks. We begin with a quick introduction to the concepts of machine learning and outline some of the most common machine learning…

Machine Learning · Computer Science 2019-09-23 Wei-Hung Weng

Machine learning (ML) is widely used in drug discovery to train models that predict protein-ligand binding. These models are of great value to medicinal chemists, in particular if they provide case-specific insight into the physical…

Biomolecules · Quantitative Biology 2022-04-14 Carl Poelking , Gianni Chessari , Christopher W. Murray , Richard J. Hall , Lucy Colwell , Marcel Verdonk

The Lifelong Multi-Label (LML) image recognition builds an online class-incremental classifier in a sequential multi-label image recognition data stream. The key challenges of LML image recognition are the construction of label…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Kaile Du , Fan Lyu , Fuyuan Hu , Linyan Li , Wei Feng , Fenglei Xu , Qiming Fu

A rapidly growing amount of content posted online, such as food recipes, opens doors to new exciting applications at the intersection of vision and language. In this work, we aim to estimate the calorie amount of a meal directly from an…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Robin Ruede , Verena Heusser , Lukas Frank , Alina Roitberg , Monica Haurilet , Rainer Stiefelhagen

Protein mutations can have profound effects on biological function, making accurate prediction of property changes critical for drug discovery, protein engineering, and precision medicine. Current approaches rely on fine-tuning…

Machine Learning · Computer Science 2025-10-27 Srivathsan Badrinarayanan , Yue Su , Janghoon Ock , Alan Pham , Sanya Ahuja , Amir Barati Farimani

Recent progress in Graph Neural Networks (GNNs) has greatly enhanced the ability to model complex molecular structures for predicting properties. Nevertheless, molecular data encompasses more than just graph structures, including textual…

Machine Learning · Computer Science 2024-06-04 Junjie Xu , Zongyu Wu , Minhua Lin , Xiang Zhang , Suhang Wang

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Understanding and leveraging the 3D structures of proteins is central to a variety of biological and drug discovery tasks. While deep learning has been applied successfully for structure-based protein function prediction tasks, current…

Machine Learning · Computer Science 2024-04-03 Rong Han , Wenbing Huang , Lingxiao Luo , Xinyan Han , Jiaming Shen , Zhiqiang Zhang , Jun Zhou , Ting Chen

When faced with learning a set of inter-related tasks from a limited amount of usable data, learning each task independently may lead to poor generalization performance. Multi-Task Learning (MTL) exploits the latent relations between tasks…

Machine Learning · Computer Science 2015-08-14 Niloofar Yousefi , Michael Georgiopoulos , Georgios C. Anagnostopoulos

Machine learning (ML) based materials discovery has emerged as one of the most promising approaches for breakthroughs in materials science. While heuristic knowledge based descriptors have been combined with ML algorithms to achieve good…

Materials Science · Physics 2021-09-28 Sadman Sadeed Omee , Steph-Yves Louis , Nihang Fu , Lai Wei , Sourin Dey , Rongzhi Dong , Qinyang Li , Jianjun Hu

Multi-task learning (MTL) aims to build general-purpose vision systems by training a single network to perform multiple tasks jointly. While promising, its potential is often hindered by "unbalanced optimization", where task interference…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Yihang Guo , Tianyuan Yu , Liang Bai , Yanming Guo , Yirun Ruan , William Li , Weishi Zheng
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