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Machine learning (ML) refers to computer algorithms that predict a meaningful output or categorize complex systems based on a large amount of data. ML is applied in various areas including natural science, engineering, space exploration,…

Predicting molecular properties with data-driven methods has drawn much attention in recent years. Particularly, Graph Neural Networks (GNNs) have demonstrated remarkable success in various molecular generation and prediction tasks. In…

Quantitative Methods · Quantitative Biology 2021-10-19 Zaixi Zhang , Qi Liu , Hao Wang , Chengqiang Lu , Chee-Kong Lee

Large language models (LLMs) have demonstrated their strong capabilities in various domains, and have been recently integrated for graph analysis as graph language models (GLMs). With LLMs as the predictor, some GLMs can interpret unseen…

Computation and Language · Computer Science 2025-06-30 Junze Chen , Cheng Yang , Shujie Li , Zhiqiang Zhang , Yawen Li , Junping Du , Chuan Shi

Background Predicting overall survival (OS) in non-small cell lung cancer (NSCLC) is essential for clinical decision-making and drug development. While tumor and blood test markers kinetics are intrinsically linked, their joint dynamics and…

Quantitative Methods · Quantitative Biology 2026-01-19 Ruben Taieb , René Bruno , Pascal Chanu , Jin Yan Jin , Sébastien Benzekry

Medical image classification involves thresholding of labels that represent malignancy risk levels. Usually, a task defines a single threshold, and when developing computer-aided diagnosis tools, a single network is trained per such…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Vadim Ratner , Yoel Shoshan , Tal Kachman

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

Foundation Models (FMs) serve as a general class for the development of artificial intelligence systems, offering broad potential for generalization across a spectrum of downstream tasks. Despite extensive research into self-supervised…

Machine Learning · Computer Science 2024-06-17 Yuhao Xu , Xinqi Liu , Keyu Duan , Yi Fang , Yu-Neng Chuang , Daochen Zha , Qiaoyu Tan

To enable personalized cancer treatment, machine learning models have been developed to predict drug response as a function of tumor and drug features. However, most algorithm development efforts have relied on cross validation within a…

Leukemia, the cancer of blood cells, originates in the blood-forming cells of the bone marrow. In Chronic Myeloid Leukemia (CML) conditions, the cells partially become mature that look like normal white blood cells but do not resist…

Genomics · Quantitative Biology 2023-02-09 Madiha Hameed , Muhammad Bilal , Tuba Majid , Abdul Majid , Asifullah Khan

Machine learning force fields (MLFFs) are gradually evolving towards enabling molecular dynamics simulations of molecules and materials with ab initio accuracy but at a small fraction of the computational cost. However, several challenges…

Tabular data is foundational to predictive modeling in various crucial industries, including healthcare, finance, retail, sustainability, etc. Despite the progress made in specialized models, there is an increasing demand for universal…

Machine Learning · Computer Science 2024-07-12 Xumeng Wen , Han Zhang , Shun Zheng , Wei Xu , Jiang Bian

Molecular machine learning (ML) has proven important for tackling various molecular problems, such as predicting molecular properties based on molecular descriptors or fingerprints. Since relatively recently, graph neural network (GNN)…

Machine Learning · Computer Science 2023-09-06 Alexander Kensert , Gert Desmet , Deirdre Cabooter

Upon the significant performance of the supervised deep neural networks, conventional procedures of developing ML system are \textit{task-centric}, which aims to maximize the task accuracy. However, we scrutinized this \textit{task-centric}…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Kyung Ho Park , Hyunhee Chung , Soonwoo Kwon

The recent development of high-throughput sequencing creates a large collection of multi-omics data, which enables researchers to better investigate cancer molecular profiles and cancer taxonomy based on molecular subtypes. Integrating…

Genomics · Quantitative Biology 2024-01-25 Bingjun Li , Sheida Nabavi

We present a perspective on molecular machine learning (ML) in the field of chemical process engineering. Recently, molecular ML has demonstrated great potential in (i) providing highly accurate predictions for properties of pure components…

Chemical Physics · Physics 2025-09-01 Jan G. Rittig , Manuel Dahmen , Martin Grohe , Philippe Schwaller , Alexander Mitsos

Multi-kernel learning (MKL) has been widely used in function approximation tasks. The key problem of MKL is to combine kernels in a prescribed dictionary. Inclusion of irrelevant kernels in the dictionary can deteriorate accuracy of MKL,…

Machine Learning · Computer Science 2021-02-10 Pouya M Ghari , Yanning Shen

Surfactants are key ingredients in foaming and cleansing products across various industries such as personal and home care, industrial cleaning, and more, with the critical micelle concentration (CMC) being of major interest. Predictive…

The adoption of machine learning (ML) and deep learning methods has revolutionized molecular medicine by driving breakthroughs in genomics, transcriptomics, drug discovery, and biological systems modeling. The increasing quantity,…

Deep learning is an important method for molecular design and exhibits considerable ability to predict molecular properties, including physicochemical, bioactive, and ADME/T (absorption, distribution, metabolism, excretion, and toxicity)…

Molecular Networks · Quantitative Biology 2022-05-10 Hanxuan Cai , Huimin Zhang , Duancheng Zhao , Jingxing Wu , Ling Wang

Geometric deep learning (GDL) has demonstrated huge power and enormous potential in molecular data analysis. However, a great challenge still remains for highly efficient molecular representations. Currently, covalent-bond-based molecular…

Computational Physics · Physics 2023-06-28 Cong Shen , Jiawei Luo , Kelin Xia
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