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We study the problem of independence and conditional independence tests between categorical covariates and a continuous response variable, which has an immediate application in genetics. Instead of estimating the conditional distribution of…

Methodology · Statistics 2015-05-05 Bo Jiang , Chao Ye , Jun S. Liu

Diffusion models have emerged as a dominant framework for generative modeling, but their mathematical foundations are often presented separately through diffusion probabilistic models, score-based modeling, stochastic differential…

Machine Learning · Computer Science 2026-05-29 Jiayi Fu , Yuxia Wang

This paper introduces a statistical treatment of inverse problems constrained by models with stochastic terms. The solution of the forward problem is given by a distribution represented numerically by an ensemble of simulations. The goal is…

Optimization and Control · Mathematics 2019-04-17 Emil M. Constantinescu , Noemi Petra , Julie Bessac , Cosmin G. Petra

This paper investigates score-based diffusion models when the underlying target distribution is concentrated on or near low-dimensional manifolds within the higher-dimensional space in which they formally reside, a common characteristic of…

Machine Learning · Computer Science 2025-01-03 Gen Li , Yuling Yan

This paper explores the use of score-based diffusion models for Bayesian image reconstruction. Diffusion models are an efficient tool for generative modeling. Diffusion models can also be used for solving image reconstruction problems. We…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Michael T. McCann , Hyungjin Chung , Jong Chul Ye , Marc L. Klasky

Diffusion models (DMs) create samples from a data distribution by starting from random noise and iteratively solving a reverse-time ordinary differential equation (ODE). Because each step in the iterative solution requires an expensive…

Machine Learning · Computer Science 2025-02-25 Eric Frankel , Sitan Chen , Jerry Li , Pang Wei Koh , Lillian J. Ratliff , Sewoong Oh

For $\mathcal{O}$ a bounded domain in $\mathbb{R}^d$ and a given smooth function $g:\mathcal{O}\to\mathbb{R}$, we consider the statistical nonlinear inverse problem of recovering the conductivity $f>0$ in the divergence form equation $$…

Statistics Theory · Mathematics 2020-03-09 Matteo Giordano , Richard Nickl

Neural Posterior Estimation methods for simulation-based inference can be ill-suited for dealing with posterior distributions obtained by conditioning on multiple observations, as they tend to require a large number of simulator calls to…

Machine Learning · Computer Science 2023-07-11 Tomas Geffner , George Papamakarios , Andriy Mnih

Recent score-based diffusion models (SBDMs) show promising results in unpaired image-to-image translation (I2I). However, existing methods, either energy-based or statistically-based, provide no explicit form of the interfered intermediate…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Shikun Sun , Longhui Wei , Junliang Xing , Jia Jia , Qi Tian

Discrete-time diffusion-based generative models and score matching methods have shown promising results in modeling high-dimensional image data. Recently, Song et al. (2021) show that diffusion processes that transform data into noise can…

Machine Learning · Computer Science 2021-10-01 Chin-Wei Huang , Jae Hyun Lim , Aaron Courville

Unnormalized probability distributions are central to modeling complex physical systems across various scientific domains. Traditional sampling methods, such as Markov Chain Monte Carlo (MCMC), often suffer from slow convergence, critical…

Machine Learning · Computer Science 2025-10-27 Vikas Kanaujia , Vipul Arora

Inspired by the combination of feedforward and iterative computations in the virtual cortex, and taking advantage of the ability of denoising autoencoders to estimate the score of a joint distribution, we propose a novel approach to…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Adriana Romero , Michal Drozdzal , Akram Erraqabi , Simon Jégou , Yoshua Bengio

In the realm of medical imaging, inverse problems aim to infer high-quality images from incomplete, noisy measurements, with the objective of minimizing expenses and risks to patients in clinical settings. The Diffusion Models have recently…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Hossein Askari , Fred Roosta , Hongfu Sun

Diffusion models have emerged as a powerful framework in generative modeling, typically relying on optimizing neural networks to estimate the score function via forward SDE simulations. In this work, we propose an alternative method that is…

Numerical Analysis · Mathematics 2025-06-17 Yuehaw Khoo , Mathias Oster , Yifan Peng

We consider the recovery of an unknown function $f$ from a noisy observation of the solution $u_f$ to a partial differential equation that can be written in the form $\mathcal{L} u_f=c(f,u_f)$, for a differential operator $\mathcal{L}$ that…

Statistics Theory · Mathematics 2024-12-02 Geerten Koers , Botond Szabo , Aad van der Vaart

We propose to solve inverse problems involving the temporal evolution of physics systems by leveraging recent advances from diffusion models. Our method moves the system's current state backward in time step by step by combining an…

Machine Learning · Computer Science 2023-12-06 Benjamin J. Holzschuh , Simona Vegetti , Nils Thuerey

Recent advances in generative artificial intelligence have had a significant impact on diverse domains spanning computer vision, natural language processing, and drug discovery. This work extends the reach of generative models into physical…

Machine Learning · Computer Science 2024-10-22 Christian Jacobsen , Yilin Zhuang , Karthik Duraisamy

The incorporation of generative models as regularisers within variational formulations for inverse problems has proven effective across numerous image reconstruction tasks. However, the resulting optimisation problem is often non-convex and…

Machine Learning · Computer Science 2024-08-14 Pascal Fernsel , Željko Kereta , Alexander Denker

Diffusion models are widely used as priors in imaging inverse problems. However, their performance often degrades under distribution shifts between the training and test-time images. Existing methods for identifying and quantifying…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Shirin Shoushtari , Edward P. Chandler , Yuanhao Wang , M. Salman Asif , Ulugbek S. Kamilov

Diffusion Inverse Solvers (DIS) are designed to sample from the conditional distribution $p_{\theta}(X_0|y)$, with a predefined diffusion model $p_{\theta}(X_0)$, an operator $f(\cdot)$, and a measurement $y=f(x'_0)$ derived from an unknown…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Tongda Xu , Ziran Zhu , Jian Li , Dailan He , Yuanyuan Wang , Ming Sun , Ling Li , Hongwei Qin , Yan Wang , Jingjing Liu , Ya-Qin Zhang
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