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Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

World models have emerged as a unifying paradigm for learning latent dynamics, simulating counterfactual futures, and supporting planning under uncertainty. In this paper, we argue that computational epidemiology is a natural and…

Machine Learning · Computer Science 2026-04-14 Zeeshan Memon , Yiqi Su , Christo Kurisummoottil Thomas , Walid Saad , Liang Zhao , Naren Ramakrishnan

Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements,…

Physics and Society · Physics 2021-07-26 Wesley Cota , David Soriano-Paños , Alex Arenas , Silvio C. Ferreira , Jesús Gómez-Gardeñes

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

Epidemics exhibit interconnected processes that operate at multiple time and organizational scales, a hallmark of complex adaptive systems. Modern epidemiological modeling frameworks incorporate feedback between individual-level behavioral…

Dynamical Systems · Mathematics 2025-03-07 Baltazar Espinoza , Roger Sanchez , Jimmy Calvo-Monge , Fabio Sanchez

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

Augmenting classical epidemiological models with information from the social sciences helps unveil the interplay between contagion dynamics and social responses. However, multidisciplinary integration of social analysis and epidemiological…

Physics and Society · Physics 2025-07-29 Daniele Proverbio , Riccardo Tessarin , Giulia Giordano

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

Populations and Evolution · Quantitative Biology 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou

Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…

Populations and Evolution · Quantitative Biology 2026-04-14 Michael J. Plank , Matt Ryan , Lloyd Chapman , Roslyn I. Hickson , Thomas House , Emma McBryde , James M. McCaw

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

Social and Information Networks · Computer Science 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

The recent COVID-19 pandemic has led to an increasing interest in the modeling and analysis of infectious diseases. The pandemic has made a significant impact on the way we behave and interact in our daily life. The past year has witnessed…

Computer Science and Game Theory · Computer Science 2021-06-17 Shutian Liu , Yuhan Zhao , Quanyan Zhu

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

Populations and Evolution · Quantitative Biology 2023-08-04 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua S. Weitz , Andrew A. Peterson

We study contact epidemic models for the spread of infective diseases in finite populations. The size dependence enters in the infection rate. The dynamics of such models is then analyzed within the deterministic approximation, as well as…

Populations and Evolution · Quantitative Biology 2020-04-07 Ph. Blanchard , S. Nicolis

This paper gives an introduction to rule-based modelling applied to topics in infectious diseases. Rule-based models generalise reaction-based models with reagents that have internal state and may be bound together to form complexes, as in…

Populations and Evolution · Quantitative Biology 2021-08-10 William Waites , Matteo Cavaliere , David Manheim , Jasmina Panovska-Griffiths , Vincent Danos

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

Network epidemiology has become a core framework for investigating the role of human contact patterns in the spreading of infectious diseases. In network epidemiology represents the contact structure as a network of nodes (individuals)…

Populations and Evolution · Quantitative Biology 2014-06-10 Petter Holme

We present and analyze a mathematical model to study the feedback between behavior and epidemic spread in a population that is actively assessing and reacting to risk of infection. In our model, a population dynamically forms an opinion…

Dynamical Systems · Mathematics 2025-03-20 Marcela Ordorica Arango , Anastasia Bizyaeva , Simon A. Levin , Naomi Ehrich Leonard

We present two new models for interacting populations subject to a transmissible disease. The novelty lies in the assumption that herd behavior influences the disease incidence, rather than the demographic description of the interactions,…

Dynamical Systems · Mathematics 2014-05-19 Ezio Venturino

From pathogens and computer viruses to genes and memes, contagion models have found widespread utility across the natural and social sciences. Despite their success and breadth of adoption, the approach and structure of these models remain…